Advancement in research on relationship between interleukin-1 family and endometriosis
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This review examines the role of interleukin-1 in endometriosis implantation, proliferation, and invasion while noting that whether elevated IL-1 initiates the disease or results from it remains unresolved.
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Abstract
At present, the exact pathogenesis of endometriosis (EMs) remains uncertain. However, more and more researches support that interleukin-1 (IL-1) plays an important role in implantation, proliferation and invasion of endometrial cells along with retrograde menstruation. However, whether increased IL-1 is the initiator of EMs or the disease causes increase of IL-1 or they develop simultaneously, still needs more investigations.
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
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