Bioelectronic Medicine in the Rehabilitation of Diseases: Opportunities and Challenges

Bioelectronic medicine is a discipline that uses various electronic devices and technologies to diagnose, treat, and monitor life systems and diseases. We briefly outline the discovery process of common electrophysiological signals in the human body and focus on various electrical stimulation technologies. We discuss their applications in the nervous system, cancer treatment, tissue regeneration and repair, and cardiovascular system treatment. These applications often combine electrical stimulation with nanomaterials. With continuous technological development, various bioelectronic devices can be used for independent therapeutic intervention or adjunct treatment, and their applications are increasing. In addition, the development of bioelectronic medicine has benefited from artificial intelligence methods based on machine learning. We further discuss the huge potential of rapidly advancing artificial intelligence and big data analysis technologies in rehabilitation treatment and the expansion of bioelectronic medicine applications. We also discuss the limitations of each technology and future prospects.