Meeting the needs of young women with secondary amenorrhea and spontaneous premature ovarian failure

Nahrain H. Alzubaidi
In: Obstetrics & Gynecology · 2002 · vol. 99(5) , pp. 720–725 · doi:10.1016/s0029-7844(02)01962-2 · PMID:11978278 · W2090848028
article OA: closed CC0 ⤵ 12 in-corpus citations
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This study surveyed 50 young women with spontaneous premature ovarian failure and found menstrual disturbance as the most common symptom, with delayed diagnosis and a desire for more aggressive evaluation and patient education.

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Abstract

OBJECTIVE: To investigate the experiences of young women with spontaneous premature ovarian failure with regard to the initial presenting symptom, promptness of diagnosis, and patient education. METHODS: We asked 50 patients previously diagnosed with spontaneous premature ovarian failure to participate in a structured interview survey consisting of 38 true-or-false, multiple-choice, and open-ended questions. RESULTS: Disturbance in menstrual pattern was the most common initial symptom in the 48 women who completed the interview (44 of 48, 92%). Over half of the 44 women who presented with this complaint reported visiting a clinician's office three or more times before laboratory testing was performed to determine the diagnosis. Over half of them reported seeing three or more different clinicians before diagnosis. In 25% of women it took longer than 5 years for the diagnosis of premature ovarian failure to be established. Patients who spent more than 5 minutes with the clinician discussing the diagnosis were significantly more likely to be satisfied with the manner in which they were informed (P <.001). Ninety percent of participants were college graduates, and 40% had graduate degrees. CONCLUSION: Women with spontaneous premature ovarian failure perceived a need for more aggressive evaluation of secondary amenorrhea and oligomenorrhea. Loss of menstrual regularity can be a sign of ovarian insufficiency, and the associated estrogen deficiency is a well-established risk factor for osteoporosis.

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