The levonorgestrel-releasing intrauterine system in modern gynaecology.

McGavigan CJ, Owen P
British journal of hospital medicine (London, England : 2005) · 2005 · doi:10.12968/hmed.2005.66.10.19896 · PMID:16255257
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This review article examines the evolution of the levonorgestrel-releasing intrauterine system from its origins in contraception to its current broad application in treating various gynecological conditions. The authors note that while compliance can be affected by side effects such as breakthrough bleeding, appropriate patient counseling helps mitigate unnecessary discontinuation. Although the text provided is limited to an abstract and does not detail specific disease outcomes, it positions the device within modern gynecological practice. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

The levonorgestrel-releasing intrauterine system was initially developed for contraception but is now widely used for a variety of gynaecological conditions. Compliance can sometimes be hampered by troublesome side effects (principally breakthrough bleeding) but appropriate counselling can reduce unnecessary discontinuation.
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British Journal of Hospital Medicine (BJHM) is published by IMR Press from Volume 87 Issue 1 (2026). Previous articles were published by another publisher under the hybrid model (CC-BY-NC license or on a subscription basis), and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement. The levonorgestrel-releasing intrauterine system in modern gynaecology C Jay McGavigan 1, Philip Owen 1 Affiliation Article Info 1 Department of Gynaecology, Glasgow Royal Infirmary, Glasgow G4 0SF Abstract The levonorgestrel-releasing intrauterine system was initially developed for contraception but is now widely used for a variety of gynaecological conditions. Compliance can sometimes be hampered by troublesome side effects (principally breakthrough bleeding) but appropriate counselling can reduce unnecessary discontinuation.

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last seen: 2026-08-23T09:30:01.253652+00:00