Imaging of the Urachus

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This paper is a radiology review describing embryology, normal anatomy, and imaging approaches (ultrasonography, CT, MRI, and fluoroscopy) for the urachus, followed by a catalog of congenital anomalies, inflammatory/infectious processes, nonneoplastic masses, malignant tumors, and key mimics. It highlights that urachal pathology can present with a range of structural patterns identifiable on cross-sectional imaging, and it specifically includes “urachal endometriosis” among nonneoplastic inflammatory and mass-like conditions. A stated limitation is that the article is an imaging-focused overview rather than new comparative clinical research, with no primary study population or outcomes beyond synthesis of existing imaging knowledge. Relevance to endometriosis: the review explicitly includes urachal endometriosis as a specific urachal pathological condition within a broader imaging differential, though the paper’s main focus is imaging anatomy and urachal pathology classification rather than endometriosis treatment or mechanisms.

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Abstract

The urachus is a remnant fibrous cord of the allantois and the ventral aspect of the cloaca that connects the urinary bladder to the anterior abdominal wall at the level of the umbilicus. The authors explore the embryologic origins of the urachus and delineate its normal anatomy, followed by a discussion of urachal pathologic conditions seen with different imaging modalities-including US, CT, and MRI-using a case-based approach. Although it is a vestigial structure, the urachus can harbor significant disease, including congenital anomalies arising secondary to varying degrees of incomplete involution of the urachus and ranging from focal patency (urachal cyst, diverticulum, and sinus) to complete patency (patent urachus). The spectrum of congenital abnormalities can manifest with various clinical findings and is often discovered at imaging when infected. Understanding the embryogenesis of the urachus is therefore crucial for understanding the imaging manifestations of urachal abnormalities. Nonneoplastic urachal masses can be inflammatory and sometimes difficult to differentiate from malignancy. In women, the urachus can be involved by endometriosis. Neoplastic urachal entities can include mucinous cystadenoma, which can rupture with associated mucinous ascites. Adenocarcinoma is the most common urachal malignancy and frequently can extend to involve the urinary bladder. Other malignant urachal entities include urothelial carcinoma and metastasis. Mimics of urachal pathologic conditions can cause diagnostic misperception and include primary bladder malignancy, infections, and dropped gallstones or appendicoliths. This comprehensive overview aims to enhance radiologists' proficiency in recognizing and interpreting urachal abnormalities, thus contributing to improved patient outcomes. ©RSNA, 2025 Supplemental material is available for this article.
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Introduction

Urachal Embryogenesis Imaging Techniques and Normal Urachal Imaging Anatomy Ultrasonography CT and MRI Fluoroscopy Urachal Pathologic Conditions Congenital Urachal Anomalies Patent Urachus Umbilical-Urachal Sinus Tract Vesicourachal Diverticulum Urachal Cyst Urachal Infection and Inflammatory Conditions Primary Infection Acquired Urachal Fistula Nonneoplastic Urachal Masses Urachal Endometriosis Inflammatory Pseudomass Urachal Hematoma Neoplastic Urachal Masses Benign Masses Malignant Masses Mimics of Urachal Pathologic Conditions Primary Bladder Urothelial Malignancy Bladder Schistosomiasis Fallen Stones in the Peritoneal Cavity

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Information & Authors Information Published In Abbreviations - GRE - gradient-echo - MUL - median umbilical ligament - 3D - three-dimensional Copyright History Authors Disclosures of conflicts of interest.— Metrics & Citations Metrics Article Usage Altmetrics Citations Export citation Select the format you want to export the citation of this publication. Cited by View Options To read the full-text, please use one of the options below to sign in or purchase access. RSNA members have free access to all RadioGraphics content. However, complimentary journal-based CME activities are only included for members with the Standard or Full Access packages. RSNA Journals participate in the World Health Organization's Research4Life program and the online versions of the journals are either freely available or are available with low-cost access to not-for-profit institutions in eligible countries. Login options Check if you have access through your login credentials or your institution to get full access on this article. Purchase Options Subscribe and get full access to this article. Recommend this journal to your librarian To read the full-text, please use one of the options below to sign in or purchase access. RSNA members have free access to all RadioGraphics content. However, complimentary journal-based CME activities are only included for members with the Standard or Full Access packages. RSNA Journals participate in the World Health Organization's Research4Life program and the online versions of the journals are either freely available or are available with low-cost access to not-for-profit institutions in eligible countries. Recommend to a librarian Recommend this journal to your librarian Redeem Voucher Access tokens allow you to activate and access content online. If you have been issued an access token, please enter it here and click 'Submit':

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endometriosis

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Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging Diagnostic Imaging

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