Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study

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Methods The study was conducted between 28th March to 30th April 2020. We recruited 50 individuals who have a history of chronic health issues, and 50 individuals with no health issues for this cross-sectional study. Three questionnaires were used to evaluate the mental health [depression anxiety stress scale (DASS-21)], sleep quality [Pittsburgh sleep quality index (PSQI)], and QoL [short form of health-related questionnaire (SF-36)] of the participants. Statistical analysis was carried out with Student’s t-test, using SPSS software v16. Results Baseline demographic characteristics were homogenous for both groups of participants. Intergroup analysis revealed statistically significant differences in mental health (p<0.001), sleep quality (p<0.001), and QoL (p<0.001) between the two groups. The results showed high levels of depression, anxiety and stress; poor sleep quality and low health-related QoL in Group A as compared to Group B. Conclusion Our findings indicate that individuals with chronic health issues exhibit higher mental health problems, lower quality of sleep and have a lower health-related QoL. More research is required and also government should plan on taking care of those patients. " } { "@context": "http://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": "1", "item": { "@id": "https://f1000research.com/", "name": "Home" } }, { "@type": "ListItem", "position": "2", "item": { "@id": "https://f1000research.com/browse/articles", "name": "Browse" } }, { "@type": "ListItem", "position": "3", "item": { "@id": "https://f1000research.com/articles/9-718/v3", "name": "Mental health, sleep quality and quality of life in individuals with..." } } ] } Home Browse Mental health, sleep quality and quality of life in individuals with... ALL Metrics - Views Downloads Get PDF Get XML Cite How to cite this article Patra RC, Kanungo B and Bawa P. Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.12688/f1000research.24321.3 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. Close Copy Citation Details Export Export Citation Sciwheel EndNote Ref. Manager Bibtex ProCite Sente EXPORT Select a format first Track Share ▬ ✚ Research Article Revised Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] Ramesh Chandra Patra https://orcid.org/0000-0001-5287-8833 1 , Biswajit Kanungo 1 , Parul Bawa 1 Ramesh Chandra Patra https://orcid.org/0000-0001-5287-8833 1 , Biswajit Kanungo 1 , Parul Bawa 1 PUBLISHED 29 Jul 2024 Author details Author details 1 Department of Physiotherapy, Lovely Professional University, Jalandhar, Punjab, 144001, India Ramesh Chandra Patra Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization Biswajit Kanungo Roles: Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Parul Bawa Roles: Writing – Review & Editing OPEN PEER REVIEW DETAILS REVIEWER STATUS This article is included in the Emerging Diseases and Outbreaks gateway. This article is included in the Coronavirus (COVID-19) collection. Abstract Background Since the World Health Organization (WHO) declared the COVID-19 outbreak a global pandemic and the global spread had created several challenges for the general public and the healthcare workers across the world, the primary aim of this study was to assess the psychological stress, sleep quality, and health-related quality of life (QoL) of individuals with multiple health issues during home quarantine caused by the COVID-19 pandemic. Methods The study was conducted between 28 th March to 30 th April 2020. We recruited 50 individuals who have a history of chronic health issues, and 50 individuals with no health issues for this cross-sectional study. Three questionnaires were used to evaluate the mental health [depression anxiety stress scale (DASS-21)], sleep quality [Pittsburgh sleep quality index (PSQI)], and QoL [short form of health-related questionnaire (SF-36)] of the participants. Statistical analysis was carried out with Student’s t-test, using SPSS software v16. Results Baseline demographic characteristics were homogenous for both groups of participants. Intergroup analysis revealed statistically significant differences in mental health (p<0.001), sleep quality (p<0.001), and QoL (p<0.001) between the two groups. The results showed high levels of depression, anxiety and stress; poor sleep quality and low health-related QoL in Group A as compared to Group B. Conclusion Our findings indicate that individuals with chronic health issues exhibit higher mental health problems, lower quality of sleep and have a lower health-related QoL. More research is required and also government should plan on taking care of those patients. READ ALL READ LESS Keywords COVID-19, Mental Health, Sleep Quality, Quality of Life Corresponding Author(s) Ramesh Chandra Patra ( [email protected] ) Close Corresponding author: Ramesh Chandra Patra Competing interests: No competing interests were disclosed. Grant information: The author(s) declared that no grants were involved in supporting this work. Copyright: © 2024 Patra RC et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions. How to cite: Patra RC, Kanungo B and Bawa P. Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.12688/f1000research.24321.3 ) First published: 17 Jul 2020, 9 :718 ( https://doi.org/10.12688/f1000research.24321.1 ) Latest published: 29 Jul 2024, 9 :718 ( https://doi.org/10.12688/f1000research.24321.3 ) Revised Amendments from Version 2 First, we would like to thank the honourable reviewers for their valuable comments which improved the quality of the manuscript, we corrected minor typos. The revised manuscript under the method section has added the sample size calculation. The inclusion criteria for Group B have been added in the revised version. We have mentioned the tools in the methodology section. In the statistical analysis, we have made the changes as per the reviewer's comments The study's limitations and future recommendations section have been included in the revised version. First, we would like to thank the honourable reviewers for their valuable comments which improved the quality of the manuscript, we corrected minor typos. The revised manuscript under the method section has added the sample size calculation. The inclusion criteria for Group B have been added in the revised version. We have mentioned the tools in the methodology section. In the statistical analysis, we have made the changes as per the reviewer's comments The study's limitations and future recommendations section have been included in the revised version. See the authors' detailed response to the review by Shyamal Koley See the authors' detailed response to the review by Kanwar Hamza Shuja READ REVIEWER RESPONSES Introduction According to the World Health Organization (WHO), the COVID-19 outbreak is a global pandemic that started at the end of November in China and then gradually spread all over the world 1 , 2 . As neither treatment nor vaccine has been discovered for this disease, it raises concerns among the public about the spread of infection from confirmed COVID-19 positive cases. The WHO suggests that social isolation helps to limit the growing number of cases of COVID-19, and this has also led to significant fear and anxiety related to the spread of infection in the general public. Excessive fear and apprehension about the spread of infection can lead to acute stress, anxiety, and low quality of sleep 3 , 4 . Many organizations are already working to increase awareness about the societal impact of the ongoing pandemic 5 . For instance, it has been reported that during this pandemic crisis, various factors that impact the health of individuals, such as prolonged periods of social isolation, fear of unemployment, and economic loss, have the potential to increase due to lockdown 5 – 7 . The relationship between physical illness and mental health has received increased attention in recent years, and poor mental health is of concern as it may negatively affect an individual’s quality of life (QoL) 8 , 9 . Evidence suggests a direct relationship between mental health and sleep quality, a crucial public health issue 10 , 11 . This study aimed to assess the psychological stress, sleep quality, and health-related QoL of individuals with and without multiple health issues during home quarantine in India due to the COVID-19 pandemic. Methods Ethical considerations The study followed all guidelines for ethical conduct per the World Medical Association’s Declaration of Helsinki (2013) and the Good Clinical Practice (Indian Council of Medical Research). We obtained approval for the study from the Institutional Research Ethics Committee of the Lovely Professional University (LPU), Phagwara, India (LPU/IEC/2020/26/03). All the participants were informed about the data collection procedure, and a written consent form was obtained from all the participants before the study started. Study design and setting This study was an observational cross-sectional study. The study took place at the Department of Physiotherapy, LPU. The study was conducted from 28 th March to 30 th April 2020. Full lockdown in India was initiated from 28 th March to 31 st May 2020. From 31 st May, the lockdown was extended until 30 th June for certain containment zones. Participant recruitment A total of 100 participants were recruited for the study as per their medical history. A total of 50 individuals suffering from chronic health issues (Group A; as identified from their clinical records) and 50 individuals with no chronic health issues (Group B) were recruited. Sample size calculation Sample size was calculated using G power software 3.1. The estimated sample size calculated for the study was 51 (95% confidence interval, power of the study was 80% where the effect size was considered as 0.5). Individuals undergoing physio treatment at the Department of Physiotherapy, LPU (even though lockdown was going on, essential services, such as physio appointments, were continuing) were recruited for the study. Individuals were contacted via phone to ask if they would like to take part in the study. As they were supposed to take physiotherapy services from our Organization, so before starting the treatment session, they were requested to sign the consent form, fill the questionnaire and were informed about the study procedure. Group A inclusion criteria : Individuals clinically pre-diagnosed with hypertension, diabetics, and chronic musculoskeletal conditions were included in this group. Group B inclusion criteria: Individuals with no chronic health issues were included in this group. Groups A and B exclusion criteria: Individuals with history of any malignancy, recent fracture or trauma, osteoporosis, inflammatory arthritis, and/or cauda equine syndrome were excluded from this study. Outcome measures Mental health. Depression, anxiety, and stress scale (DASS-21) 12 was used to assess depression, anxiety, and stress. The participants were asked to utilize a four-point severity/frequency scale to show the level of depression, anxiety, and stress they were experiencing in the past week. Sleep quality. Sleep quality was evaluated through the Pittsburgh Sleep Quality Index (PSQI) 13 . This index asked participants to answer questions about their sleep habits in the past month. Participants that scored more than 5 were defined as having a low sleep quality. Quality of life. Health-related QoL was assessed using the MOS 36-item short-form health survey (SF-36) 14 . The 36 items reflect eight health-related aspects that participants are asked to score, where 100 is defined as perfect health less, and any score less than 100 is defined as poor health. Statistical analysis Baseline characteristics of categorical variables were evaluated using the Chi-square test. Quantitative variables were evaluated using Student’s t-test, and quantitative variables without normal distribution were measured using the Mann-Whitney U test. Intergroup outcome measures were evaluated through an unpaired t-test. All analyses were carried out on SPSS software v16. Results A total of 110 participants were selected for primary assessment; 10 individuals were excluded as they did not fulfill the inclusion criteria. In total, 50 participants with chronic health issues and 50 without health issues were evaluated for the study. Demographic characteristics are shown in Table 1 . There was no statistical difference between groups for demographic characteristics. Table 1. Demographic characteristics of all patients. Group A (n=50) Group B (n=50) Age (years, mean) 53.44 52.76 Weight (kg, mean) 65.87 66.45 Height (cm, mean) 163.33 165.33 Gender (%) Female 70 50 Male 30 50 Body mass index (kg/m2, mean) 24.15 23.51 Smoking history (%) No 82 75 Yes 18 25 Marital status (%) Married 90 85 Not married 10 15 Education history (%) School level 20 10 Undergraduate 60 40 Postgraduate 20 50 Socioeconomic status Poor 0 0 Average 60 50 High 40 50 Group A, individuals with chronic health issues; Group B, individuals without chronic health issues. Socioeconomic status was calculated as follows: Poor, below Rs 15000/month; average, Rs 15000–100000/month; high, above Rs 100000/month. Table 2 presents Groups A and B scores for the three outcome measures (mental health, sleep quality, and health-related QoL). For all DASS-21 items (mental health), Group A scored higher than Group B, showing higher levels of depression, anxiety, and stress in Group A individuals. Similarly, for PSQI, Group A scored higher than Group B, showing poorer sleep quality for Group A individuals. For all SF-26 items, Group A scored lower than Group B, revealing lower health-related QoL in Group A individuals. Unpaired t-tests showed statistically significant differences between the groups for all variables ( p = 0.001). Table 2. Comparison of outcome measures for Group A and Group B. Outcome measures Group A (mean±sd) Group B (mean±sd) F-value P value Mental health (DASS-21) Depression 11.28±2.32 5.23±1.23 0.89 0.001 Anxiety 11.14±4.74 3.76±2.79 0.95 0.001 Stress 18.58±3.44 4.34±1.88 0.51 0.001 PSQI Sleep Quality 9.44±2.74 5.24±2.82 0.81 0.001 Quality of life (SF-36) * PF 45.21±8.53 90.44±12.786 0.55 0.001 RL-PH 25.50±16.83 63.51±10.73 0.56 0.001 RL-EH 32.52±22.23 79.46±11.52 0.69 0.001 ENG 30.50±7.72 84.43±8.92 0.85 0.001 EWB 42.88±8.76 83.96±9.32 0.71 0.001 BP 40.00±9.37 80.28±13.45 0.85 0.001 GH 35.52±9.49 73.80±12.72 0.61 0.001 Sd: standard deviation, PF: physical functioning, RL-PH: role of limitation-physical health, RL-EH: role of limitation-emotional health, EN: energy, EWB: emotional well-being, BP: Body pain, GH: general health, DASS=Depression Anxiety Stress Scale, PSQI= Pittsburgh Sleep Quality Index, *Social life (SL) domain was not considered for this study. Group A is individuals with chronic health issues; Group B is individuals without chronic health issues. Discussion Since the WHO declared the COVID-19 outbreak a global pandemic, many individuals, even those who have not been infected by the virus, are required to follow government rules where it was mandatory to stay at home. In this cross-sectional study, we sought to identify the correlation between chronic health issues and depression, anxiety, stress, quality of sleep and QoL in a population-based study in India during lockdown due to COVID-19. Our findings showed that poor mental health, low sleep quality, and low health-related QoL were higher in individuals with chronic health issues compared with individuals without chronic health issues at the time of home quarantine in India. Current evidence reveals that COVID-19 causes fear among the Indian population as they are at home quarantined due to lockdown, which can impact wellbeing, increasing depression, anxiety, stress, reducing sleep quality, and decreasing sleep QoL 15 , 16 . Considering that the lockdown is likely to last for weeks, there is an urgent need to monitor the psycho-physiological wellbeing of the population and to collect research data to develop evidence-based strategies to reduce the negative psychological effects of these unprecedented changes in individuals’ everyday lives 17 , 18 , especially in those with chronic health conditions. This study has some potential limitations: participants were recruited in only one area of India, we had a small sample size, and the only subjective outcome was considered for the study. Limitations There are inherent limitations to this study. A major limitation of this study was the small sample size. Another limitation of the study was the involvement of only a single medical center. Additional studies from multiple centers’ are warranted. Recommendations The present study substantiates that individuals with chronic illness have increased levels of depression, anxiety, stress, reduced sleep quality, and QoL compared with individuals without chronic illness during the quarantine period in India. Therefore, it is recommended that these individuals be constantly monitored for their psychological wellbeing during quarantine. To further substantiate the research, large comprehensive multi-centric studies should be conducted. Conclusion The WHO has recommended that individuals with physical and mental disabilities need to take extra care during isolation/quarantine for COVID-19 19 . This is supported by the results of this study, which revealed an increased level of depression, anxiety, stress, and reduced sleep quality. QoL has been shown in individuals suffering from a chronic illness compared with those without chronic illness during the quarantine period in India. Data availability Underlying data Figshare: Mental Health, Sleep Quality and Quality of Life in Subjects with Multiple Health Conditions during Home Quarantine for COVID-19 Pandemic Attack: A Comparison with Healthy Subjects, https://doi.org/10.6084/m9.figshare.12612833 20 . This project contains the following underlying data: - Group A data - Group B data Data are available under the terms of the Creative Commons Zero "No rights reserved" data waiver (CC0 1.0 Public domain dedication). Acknowledgments The author would like to express heartfelt thanks to all the participants who were participated in this study. Faculty Opinions recommended References 1. Cucinotta D, Vanelli M: WHO declares COVID-19 a pandemic. Acta Biomed. 2020; 91 (1): 157–60. PubMed Abstract | Publisher Full Text | Free Full Text 2. Cascella M, Rajnik M, Cuomo A, et al. : Features, evaluation and treatment coronavirus (COVID-19). InStatpearls. StatPearls Publishing, 2020. PubMed Abstract 3. Chen H, Guo J, Wang C, et al. : Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020; 395 (10226): 809–15. PubMed Abstract | Publisher Full Text | Free Full Text 4. Wang C, Pan R, Wan X, et al. : Immediate psychological responses and associated factors during the initial stage of the 2019 Coronavirus disease (COVID-19) epidemic among the general population in China. Int J Environ Res Public Health. 2020; 17 (5): 1729. PubMed Abstract | Publisher Full Text | Free Full Text 5. Sahoo S, Bharadwaj S, Parveen S, et al. : Self-harm and COVID-19 pandemic: an emerging concern – a report of 2 cases from India. Asian J Psychiatr. 2020; 51 : 102104. PubMed Abstract | Publisher Full Text | Free Full Text 6. 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Spira AP, Covinsky K, Rebok GW, et al. : Poor sleep quality and functional decline in older women. J Am Geriatr Soc. 2012; 60 (6): 1092–8. PubMed Abstract | Publisher Full Text | Free Full Text 12. Le MT, Tran TD, Holton S, et al. : Reliability, convergent validity and factor structure of the DASS-21 in a sample of Vietnamese adolescents. PLoS One. 2017; 12 (7): e0180557. PubMed Abstract | Publisher Full Text | Free Full Text 13. Hita-Contreras F, Martínez-López E, Latorre-Román PA, et al. : Reliability and validity of the Spanish version of the Pittsburgh Sleep Quality Index (PSQI) in patients with fibromyalgia. Rheumatol Int. 2014; 34 (7): 929–36. PubMed Abstract | Publisher Full Text 14. Schlenk EA, Erlen JA, Dunbar-Jacob J, et al. : Health-related quality of life in chronic disorders: a comparison across studies using the MOS SF-36. Qual Life Res. 1997; 7 (1): 57–65. PubMed Abstract | Publisher Full Text 15. Sood S: Psychological effects of the Coronavirus disease-2019 pandemic. Research & Humanities in Medical Education. 2020; 7 : 23–6. Reference Source 16. Kazmi SS, Hasan K, Talib S, et al. : COVID-19 and lockdwon: a study on the impact on mental health. SSRN 3577515. 2020. Publisher Full Text 17. Lazzerini M, Putoto G: COVID-19 in Italy: momentous decisions and many uncertainties. Lancet Glob Health. 2020; 8 (5): e641–e642. PubMed Abstract | Publisher Full Text | Free Full Text 18. Brooks SK, Webster RK, Smith LE, et al. : The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet. 2020; 395 (10227): 912–920. PubMed Abstract | Publisher Full Text | Free Full Text 19. World Health Organization: Mental health and psychosocial considerations during the COVID-19 outbreak, 18th March 2020. World Health Organization; 2020. Reference Source 20. Patra RC, Kanungo B, Bawa P: Mental Health, Sleep Quality and Quality of Life in Subjects with Multiple Health Conditions during Home Quarantine for COVID-19 Pandemic Attack: A Comparison with Healthy Subjects. figshare. Dataset. 2020. http://www.doi.org/10.6084/m9.figshare.12612833.v1 Comments on this article Comments (0) Version 3 VERSION 3 PUBLISHED 17 Jul 2020 ADD YOUR COMMENT Comment Author details Author details 1 Department of Physiotherapy, Lovely Professional University, Jalandhar, Punjab, 144001, India Ramesh Chandra Patra Roles: Conceptualization, Data Curation, Formal Analysis, Funding Acquisition, Investigation, Methodology, Project Administration, Resources, Software, Supervision, Validation, Visualization Biswajit Kanungo Roles: Software, Supervision, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Parul Bawa Roles: Writing – Review & Editing Competing interests No competing interests were disclosed. Grant information The author(s) declared that no grants were involved in supporting this work. Article Versions (3) version 3 Revised Published: 29 Jul 2024, 9:718 https://doi.org/10.12688/f1000research.24321.3 version 2 Revised Published: 30 Jun 2022, 9:718 https://doi.org/10.12688/f1000research.24321.2 version 1 Published: 17 Jul 2020, 9:718 https://doi.org/10.12688/f1000research.24321.1 Copyright © 2024 Patra RC et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions. Download Export To Sciwheel Bibtex EndNote ProCite Ref. Manager (RIS) Sente metrics Views Downloads F1000Research - - PubMed Central info_outline Data from PMC are received and updated monthly. - - Citations open_in_new 0 open_in_new 0 open_in_new SEE MORE DETAILS CITE how to cite this article Patra RC, Kanungo B and Bawa P. Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.12688/f1000research.24321.3 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS track receive updates on this article Track an article to receive email alerts on any updates to this article. TRACK THIS ARTICLE Share Open Peer Review Current Reviewer Status: ? Key to Reviewer Statuses VIEW HIDE Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Version 3 VERSION 3 PUBLISHED 29 Jul 2024 Revised Views 0 Cite How to cite this report: Wagenhäuser I. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.169415.r353430 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v3#referee-response-353430 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 30 Dec 2024 Isabell Wagenhäuser , University Hospital Würzburg, Würzburg, Germany Approved with Reservations VIEWS 0 https://doi.org/10.5256/f1000research.169415.r353430 At the beginning of the COVID-19 pandemic in India, the work presented examines the psychological effects of the lockdown on people with chronic illnesses in a controlled study compared to healthy people. - Since the lockdown conditions ... Continue reading READ ALL At the beginning of the COVID-19 pandemic in India, the work presented examines the psychological effects of the lockdown on people with chronic illnesses in a controlled study compared to healthy people. - Since the lockdown conditions were very different from country to country, it would be good to better define what lockdown meant in India in the introduction. - Please add a clear definition of the inclusion criteria in the methods. - Table 1: Are groups A and B comparable? If there are differences, this must be interpreted and taken into account statistically. Please compare the items statistically and add p-values. - The results of the study are extremely brief and incomplete. - Even if the groups are relatively comparable, statistical consideration of the various factors must be added -> what factors influence the occurrence of sleep disorders, depression, etc. (regression analysis)? - Please add to the LImitations that unbalanced gender ratio, only short period at the beginning of the pandemic. It is unclear what the situation will be in a second lockdown, e.g. in winter 2020/21, etc. - Please also discuss whether there is also literature on whether COVID-19 vaccination or infection can cause depression / sleep disorders and whether the lockdown is worth it in terms of mental risk. (e.g. Wagenhäuser I, et al., 2024 [Ref 1] or Athanasiou N, et al., 2023 [Ref 2]) Is the work clearly and accurately presented and does it cite the current literature? Partly Is the study design appropriate and is the work technically sound? Partly Are sufficient details of methods and analysis provided to allow replication by others? Partly If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Partly Are the conclusions drawn adequately supported by the results? Yes References 1. Wagenhäuser I, Reusch J, Gabel A, Mees J, et al.: The relationship between mental health, sleep quality and the immunogenicity of COVID-19 vaccinations. J Sleep Res . 2024; 33 (3): e13929 PubMed Abstract | Publisher Full Text 2. Athanasiou N, Baou K, Papandreou E, Varsou G, et al.: Association of sleep duration and quality with immunological response after vaccination against severe acute respiratory syndrome coronavirus-2 infection. J Sleep Res . 2023; 32 (1): e13656 PubMed Abstract | Publisher Full Text Competing Interests: No competing interests were disclosed. Reviewer Expertise: Epidemiology, immunology and diagnostics of acute respiratory infections I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Wagenhäuser I. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.169415.r353430 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v3#referee-response-353430 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Zaidi U. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.169415.r308385 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v3#referee-response-308385 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 16 Aug 2024 Uzma Zaidi , Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia Approved with Reservations VIEWS 0 https://doi.org/10.5256/f1000research.169415.r308385 The authors conducted the study on the initial stage of COVID-19; therefore, the significance is undeniable. Moreover, the exploration of psychological or psychologically related factors of QoL and sleep, besides health conditions is a very valuable aspect. The result allows ... Continue reading READ ALL The authors conducted the study on the initial stage of COVID-19; therefore, the significance is undeniable. Moreover, the exploration of psychological or psychologically related factors of QoL and sleep, besides health conditions is a very valuable aspect. The result allows for the recommendation of more comprehensive policymaking for people who are suffering from multiple health conditions. The authors have improved the quality of the manuscript by responding aptly to the comments of reviewers. However, some improvement or explanation is still required for the methodology, statistical analysis, and results section. Abstract: The conclusion needs some improvement. “Our findings indicate that individuals with chronic health ….. More research is required and also the government should plan on taking care of those patients.” Suggestion: “Our findings indicate that individuals with chronic health issues exhibit higher mental health problems, lower quality of sleep, and have a lower health-related QoL during the COVID-19 pandemic. More research is required and also the government should plan policies for patients with multiple health conditions.” Methods: Outcome measure: Please correct and update the description of the scoring method for MOS 36-item health-related survey. Therefore, the replication of the method will be authentic and easy. “The 36 items reflect …….., where 100 is defined as perfect health less, and any score less than 100 is defined as poor health.” Suggestion: I am sharing the description along with the citation. The scoring is from 0-100. Higher scores indicate better health status, whereas a low score presents poor health. The mean score of 50 has been considered as a cutoff score for all scales.[1] Statistical Analysis: Suggestion : In Table 1 add a column presenting the calculation of Chi-square to present statistical difference. Results: Suggestion : As researchers, it is wise to report the results in a more precise manner. According to the standardized scoring categories of DASS, mean scores of anxiety and stress of group A fall at an extremely severe level, whereas depression scores are falling in the range of severe levels. The relevant categories of DASS can be discussed in the result description for group B. It will strengthen the study findings. As in the normal population mean score of depression and anxiety is falling within the mild level. For more details check scoring categories: https://www.healthfocuspsychology.com.au/tools/dass-21/ Discussion: Suggestion : There is another very interesting result related to QoL that needs to be discussed. The highest mean score in group A is in the physical functioning (PF) domain. As all the participants were receiving physiotherapy that could be one of the reasons. Authors can address it better. The lowest mean in both of the groups can be seen in the Role of the limitation-physical health (RL-PH) domain. References 1. Ware JE: SF-36 health survey update. Spine (Phila Pa 1976) . 2000; 25 (24): 3130-9 PubMed Abstract | Publisher Full Text Competing Interests: No competing interests were disclosed. Reviewer Expertise: Clinical Psychology, Health Psychology, Personality Psychology, Mental Illness, Neuropsychology, Organizational Behavior I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Zaidi U. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.169415.r308385 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v3#referee-response-308385 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Version 2 VERSION 2 PUBLISHED 30 Jun 2022 Revised Views 0 Cite How to cite this report: Zaidi U. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.80174.r167559 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v2#referee-response-167559 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 21 Apr 2023 Uzma Zaidi , Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia Approved with Reservations VIEWS 0 https://doi.org/10.5256/f1000research.80174.r167559 The authors conducted the study on the initial stage of COVID-19; therefore, the significance is undeniable. Moreover, the exploration of psychological or psychologically related factors of QoL and sleep, besides health conditions is a very valuable aspect. The result allows ... Continue reading READ ALL The authors conducted the study on the initial stage of COVID-19; therefore, the significance is undeniable. Moreover, the exploration of psychological or psychologically related factors of QoL and sleep, besides health conditions is a very valuable aspect. The result allows for the recommendation of more comprehensive policy making for people who are suffering from multiple health conditions. The authors have improved the quality of the manuscript by responding aptly to the comments of reviewers. However, some improvement or explanation is still required for the methodology, statistical analysis, and results section. Abstract: The conclusion needs some improvement. “Our findings indicate that individuals with chronic health ….. More research is required and also the government should plan on taking care of those patients.” Suggestion: “Our findings indicate that individuals with chronic health ...... More research is required and also the government should plan policies for patients with multiple health conditions.” Methods: Outcome measure: Please correct and update the description of the scoring method for MOS 36-item health-related survey. Therefore, the replication of the method will be authentic and easy. “The 36 items reflect …….., where 100 is defined as perfect health less, and any score less than 100 is defined as poor health.” Suggestion: I am sharing the description along with the citation. The scoring is from 0-100. Higher scores indicate better health status, whereas a low score presents poor health. The mean score of 50 has been considered as a cutoff score for all scales 1 . Statistical Analysis: Suggestion : In Table 1 add a column presenting the calculation of Chi-square. Add a source for socioeconomic slabs in the footnote of Table 1. Authors are reporting that “Quantitative variables were evaluated using Student’s t-test, and quantitative variables without normal distribution were measured using the Mann-Whitney U test.” However, table 2 does not present the student t-test and Mann-Whitney U test explicitly. Suggestion : Provide an SD column for both groups, remove the difference column, and add a column for 't' or 'U' before the P value. Results: Suggestion : As researchers, it is wise to report the results in a more precise manner. According to the standardized scoring categories of DASS, mean scores of anxiety and stress of group A fall at an extremely severe level, whereas depression scores are falling in the range of severity levels. The relevant categories of DASS can be discussed in the result description for group B. It will strengthen the study findings. As in the normal population mean score of depression and anxiety is falling within the mild level. For more details, check scoring categories . Discussion: Suggestion : There is another very interesting result related QoL that needs to be discussed. The highest mean score in group A is in the physical functioning (PF) domain. As all the participants were receiving physiotherapy that could be one of the reasons. Authors can address it better. The lowest mean in both of the groups can be seen in the Role of the limitation-physical health (RL-PH) domain. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Partly If applicable, is the statistical analysis and its interpretation appropriate? Partly Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes References 1. Ware JE: SF-36 health survey update. Spine (Phila Pa 1976) . 2000; 25 (24): 3130-9 PubMed Abstract | Publisher Full Text Competing Interests: No competing interests were disclosed. Reviewer Expertise: Clinical Psychology, Health Psychology, Personality Psychology, Mental Illness, Neuropsychology, Organizational Behavior I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Zaidi U. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.80174.r167559 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v2#referee-response-167559 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Version 1 VERSION 1 PUBLISHED 17 Jul 2020 Views 0 Cite How to cite this report: Shuja KH. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.26834.r82045 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v1#referee-response-82045 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 08 Apr 2021 Kanwar Hamza Shuja , National Institute of Psychology (NIP), Quaid-I-Azam University (New Campus), Islamabad, Pakistan; Capital University of Science and Technology (CUST), Islamabad, Pakistan Not Approved VIEWS 0 https://doi.org/10.5256/f1000research.26834.r82045 Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. However, my biggest concern with this article is ... Continue reading READ ALL Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants were inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Third the instruments used are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Fourth it would would be nice if the authors can add limitations and recommendations heading before conclusion. Thank you and good luck. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Partly If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests: No competing interests were disclosed. Reviewer Expertise: Public Health, Criminal Psychology, Clinical Psychology. I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Shuja KH. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.26834.r82045 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v1#referee-response-82045 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 07 Sep 2022 Ramesh Patra , Department of Physiotherapy, Lovely Professional University, Jalandhar, 144001, India 07 Sep 2022 Author Response First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of ... Continue reading First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of the current manuscript. We have read each reviewer’s comments carefully and, accordingly, made utmost efforts to address each comment point-by-point. We much appreciate the reviewer’s time, effort, and detailed explanations. We believe that the revised version of our manuscript is now more focused, scientific, understandable, and better arranged. All changes are highlighted with red color. Reviewer Comment: Query 1: Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. Response: Thank you for your valuable comments. We have modified the text with proper grammar usage as per your suggestions. Query 2: However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Response: The total sample taken was 100. We have calculated the sample size using G power software 3.1 which was found to be around 51 (95% confidence interval, power of the study was 80% where the effect size was considered as 0.5). The sample size calculation has been added in the revised manuscript under the method section. Query 3: Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Response: As suggested, we have included the inclusion criteria for Group B. Query 4: Third, the instruments used, are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Response: We have used the following tools to measure all the three measure outcomes. DASS-21 tool was used to measure the mental health. PSQI was used to measure sleep quality. MOS-36 was used to measure the health-related QoL. We have mentioned the tools in the methodology section and also given references. Query 5: Fourth it would be nice if the authors can add limitations and recommendations heading before conclusion. Response: We have included the limitations and recommendations as per your suggestions. First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of the current manuscript. We have read each reviewer’s comments carefully and, accordingly, made utmost efforts to address each comment point-by-point. We much appreciate the reviewer’s time, effort, and detailed explanations. We believe that the revised version of our manuscript is now more focused, scientific, understandable, and better arranged. All changes are highlighted with red color. Reviewer Comment: Query 1: Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. Response: Thank you for your valuable comments. We have modified the text with proper grammar usage as per your suggestions. Query 2: However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Response: The total sample taken was 100. We have calculated the sample size using G power software 3.1 which was found to be around 51 (95% confidence interval, power of the study was 80% where the effect size was considered as 0.5). The sample size calculation has been added in the revised manuscript under the method section. Query 3: Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Response: As suggested, we have included the inclusion criteria for Group B. Query 4: Third, the instruments used, are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Response: We have used the following tools to measure all the three measure outcomes. DASS-21 tool was used to measure the mental health. PSQI was used to measure sleep quality. MOS-36 was used to measure the health-related QoL. We have mentioned the tools in the methodology section and also given references. Query 5: Fourth it would be nice if the authors can add limitations and recommendations heading before conclusion. Response: We have included the limitations and recommendations as per your suggestions. Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 07 Sep 2022 Ramesh Patra , Department of Physiotherapy, Lovely Professional University, Jalandhar, 144001, India 07 Sep 2022 Author Response First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of ... Continue reading First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of the current manuscript. We have read each reviewer’s comments carefully and, accordingly, made utmost efforts to address each comment point-by-point. We much appreciate the reviewer’s time, effort, and detailed explanations. We believe that the revised version of our manuscript is now more focused, scientific, understandable, and better arranged. All changes are highlighted with red color. Reviewer Comment: Query 1: Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. Response: Thank you for your valuable comments. We have modified the text with proper grammar usage as per your suggestions. Query 2: However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Response: The total sample taken was 100. We have calculated the sample size using G power software 3.1 which was found to be around 51 (95% confidence interval, power of the study was 80% where the effect size was considered as 0.5). The sample size calculation has been added in the revised manuscript under the method section. Query 3: Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Response: As suggested, we have included the inclusion criteria for Group B. Query 4: Third, the instruments used, are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Response: We have used the following tools to measure all the three measure outcomes. DASS-21 tool was used to measure the mental health. PSQI was used to measure sleep quality. MOS-36 was used to measure the health-related QoL. We have mentioned the tools in the methodology section and also given references. Query 5: Fourth it would be nice if the authors can add limitations and recommendations heading before conclusion. Response: We have included the limitations and recommendations as per your suggestions. First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of the current manuscript. We have read each reviewer’s comments carefully and, accordingly, made utmost efforts to address each comment point-by-point. We much appreciate the reviewer’s time, effort, and detailed explanations. We believe that the revised version of our manuscript is now more focused, scientific, understandable, and better arranged. All changes are highlighted with red color. Reviewer Comment: Query 1: Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. Response: Thank you for your valuable comments. We have modified the text with proper grammar usage as per your suggestions. Query 2: However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Response: The total sample taken was 100. We have calculated the sample size using G power software 3.1 which was found to be around 51 (95% confidence interval, power of the study was 80% where the effect size was considered as 0.5). The sample size calculation has been added in the revised manuscript under the method section. Query 3: Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Response: As suggested, we have included the inclusion criteria for Group B. Query 4: Third, the instruments used, are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Response: We have used the following tools to measure all the three measure outcomes. DASS-21 tool was used to measure the mental health. PSQI was used to measure sleep quality. MOS-36 was used to measure the health-related QoL. We have mentioned the tools in the methodology section and also given references. Query 5: Fourth it would be nice if the authors can add limitations and recommendations heading before conclusion. Response: We have included the limitations and recommendations as per your suggestions. Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Koley S. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.26834.r73792 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v1#referee-response-73792 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 13 Nov 2020 Shyamal Koley , Department of Physiotherapy, Guru Nanak Dev University, Amritsar, India Approved VIEWS 0 https://doi.org/10.5256/f1000research.26834.r73792 The Abstract, Introduction, Methods, Results, & Discussion Portions of the article are written nicely. The only correction needed is in Acknowledgments where " The author would......" should be written as " The authors would......". References portion are written as per ... Continue reading READ ALL The Abstract, Introduction, Methods, Results, & Discussion Portions of the article are written nicely. The only correction needed is in Acknowledgments where " The author would......" should be written as " The authors would......". References portion are written as per the style of the journal and adequate and expressive. The article is timely written and carries sufficient applicability. Detailed Report: COVID-19 is a serious global pandemic which affects physical, mental, social and societal aspects of individuals of all strata of the society. The present study attempted justly in this regard. It is a very recent complication, thus not much literature would be available. Considering the above fact, the literature cited in the article was justified. It was quite difficult to collect the samples in the time of Lockdown prevailed then nationwide. Still the work would be considered as technically sound. In such type of study, the controls are not necessarily required, pre- and post-conditions may work. The methods and analyses were sound with proper replicability. Though the sample size was small (n=100), statistical analyses (using Chi-square test, Student’s t-test and Man-Whitney U test) were appropriate. The conclusion drawn in the study was adequately supported by the results. Small sample size was one of the limitations of the study. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Yes If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests: No competing interests were disclosed. Reviewer Expertise: Kinanthropometry, Biomechanics, Public Health & Lectinology. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Koley S. Reviewer Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.26834.r73792 ) The direct URL for this report is: https://f1000research.com/articles/9-718/v1#referee-response-73792 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 13 Nov 2020 Ramesh Patra , Department of Physiotherapy, Lovely Professional University, Jalandhar, 144001, India 13 Nov 2020 Author Response Thank You so much for your Valuable response and comments. Competing Interests: No competing interests were disclosed. Thank You so much for your Valuable response and comments. Thank You so much for your Valuable response and comments. Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 13 Nov 2020 Ramesh Patra , Department of Physiotherapy, Lovely Professional University, Jalandhar, 144001, India 13 Nov 2020 Author Response Thank You so much for your Valuable response and comments. Competing Interests: No competing interests were disclosed. Thank You so much for your Valuable response and comments. Thank You so much for your Valuable response and comments. Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Comments on this article Comments (0) Version 3 VERSION 3 PUBLISHED 17 Jul 2020 ADD YOUR COMMENT Comment keyboard_arrow_left keyboard_arrow_right Open Peer Review Reviewer Status info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Reviewer Reports Invited Reviewers 1 2 3 4 Version 3 (revision) 29 Jul 24 read read Version 2 (revision) 30 Jun 22 read Version 1 17 Jul 20 read read Shyamal Koley , Guru Nanak Dev University, Amritsar, India Kanwar Hamza Shuja , National Institute of Psychology (NIP), Quaid-I-Azam University (New Campus), Islamabad, Pakistan; Capital University of Science and Technology (CUST), Islamabad, Pakistan Uzma Zaidi , Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia Isabell Wagenhäuser , University Hospital Würzburg, Würzburg, Germany Comments on this article All Comments (0) Add a comment Sign up for content alerts Sign Up You are now signed up to receive this alert Browse by related subjects keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2025 Wagenhäuser I. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 30 Dec 2024 | for Version 3 Isabell Wagenhäuser , University Hospital Würzburg, Würzburg, Germany 0 Views copyright © 2025 Wagenhäuser I. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved With Reservations info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions At the beginning of the COVID-19 pandemic in India, the work presented examines the psychological effects of the lockdown on people with chronic illnesses in a controlled study compared to healthy people. - Since the lockdown conditions were very different from country to country, it would be good to better define what lockdown meant in India in the introduction. - Please add a clear definition of the inclusion criteria in the methods. - Table 1: Are groups A and B comparable? If there are differences, this must be interpreted and taken into account statistically. Please compare the items statistically and add p-values. - The results of the study are extremely brief and incomplete. - Even if the groups are relatively comparable, statistical consideration of the various factors must be added -> what factors influence the occurrence of sleep disorders, depression, etc. (regression analysis)? - Please add to the LImitations that unbalanced gender ratio, only short period at the beginning of the pandemic. It is unclear what the situation will be in a second lockdown, e.g. in winter 2020/21, etc. - Please also discuss whether there is also literature on whether COVID-19 vaccination or infection can cause depression / sleep disorders and whether the lockdown is worth it in terms of mental risk. (e.g. Wagenhäuser I, et al., 2024 [Ref 1] or Athanasiou N, et al., 2023 [Ref 2]) Is the work clearly and accurately presented and does it cite the current literature? Partly Is the study design appropriate and is the work technically sound? Partly Are sufficient details of methods and analysis provided to allow replication by others? Partly If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Partly Are the conclusions drawn adequately supported by the results? Yes References 1. Wagenhäuser I, Reusch J, Gabel A, Mees J, et al.: The relationship between mental health, sleep quality and the immunogenicity of COVID-19 vaccinations. J Sleep Res . 2024; 33 (3): e13929 PubMed Abstract | Publisher Full Text 2. Athanasiou N, Baou K, Papandreou E, Varsou G, et al.: Association of sleep duration and quality with immunological response after vaccination against severe acute respiratory syndrome coronavirus-2 infection. J Sleep Res . 2023; 32 (1): e13656 PubMed Abstract | Publisher Full Text Competing Interests No competing interests were disclosed. Reviewer Expertise Epidemiology, immunology and diagnostics of acute respiratory infections I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. reply Respond to this report Responses (0) Wagenhäuser I. Peer Review Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.169415.r353430) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/9-718/v3#referee-response-353430 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Zaidi U. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 16 Aug 2024 | for Version 3 Uzma Zaidi , Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia 0 Views copyright © 2024 Zaidi U. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved With Reservations info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The authors conducted the study on the initial stage of COVID-19; therefore, the significance is undeniable. Moreover, the exploration of psychological or psychologically related factors of QoL and sleep, besides health conditions is a very valuable aspect. The result allows for the recommendation of more comprehensive policymaking for people who are suffering from multiple health conditions. The authors have improved the quality of the manuscript by responding aptly to the comments of reviewers. However, some improvement or explanation is still required for the methodology, statistical analysis, and results section. Abstract: The conclusion needs some improvement. “Our findings indicate that individuals with chronic health ….. More research is required and also the government should plan on taking care of those patients.” Suggestion: “Our findings indicate that individuals with chronic health issues exhibit higher mental health problems, lower quality of sleep, and have a lower health-related QoL during the COVID-19 pandemic. More research is required and also the government should plan policies for patients with multiple health conditions.” Methods: Outcome measure: Please correct and update the description of the scoring method for MOS 36-item health-related survey. Therefore, the replication of the method will be authentic and easy. “The 36 items reflect …….., where 100 is defined as perfect health less, and any score less than 100 is defined as poor health.” Suggestion: I am sharing the description along with the citation. The scoring is from 0-100. Higher scores indicate better health status, whereas a low score presents poor health. The mean score of 50 has been considered as a cutoff score for all scales.[1] Statistical Analysis: Suggestion : In Table 1 add a column presenting the calculation of Chi-square to present statistical difference. Results: Suggestion : As researchers, it is wise to report the results in a more precise manner. According to the standardized scoring categories of DASS, mean scores of anxiety and stress of group A fall at an extremely severe level, whereas depression scores are falling in the range of severe levels. The relevant categories of DASS can be discussed in the result description for group B. It will strengthen the study findings. As in the normal population mean score of depression and anxiety is falling within the mild level. For more details check scoring categories: https://www.healthfocuspsychology.com.au/tools/dass-21/ Discussion: Suggestion : There is another very interesting result related to QoL that needs to be discussed. The highest mean score in group A is in the physical functioning (PF) domain. As all the participants were receiving physiotherapy that could be one of the reasons. Authors can address it better. The lowest mean in both of the groups can be seen in the Role of the limitation-physical health (RL-PH) domain. References 1. Ware JE: SF-36 health survey update. Spine (Phila Pa 1976) . 2000; 25 (24): 3130-9 PubMed Abstract | Publisher Full Text Competing Interests No competing interests were disclosed. Reviewer Expertise Clinical Psychology, Health Psychology, Personality Psychology, Mental Illness, Neuropsychology, Organizational Behavior I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. reply Respond to this report Responses (0) Zaidi U. Peer Review Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.169415.r308385) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/9-718/v3#referee-response-308385 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2023 Zaidi U. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 21 Apr 2023 | for Version 2 Uzma Zaidi , Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia 0 Views copyright © 2023 Zaidi U. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved With Reservations info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The authors conducted the study on the initial stage of COVID-19; therefore, the significance is undeniable. Moreover, the exploration of psychological or psychologically related factors of QoL and sleep, besides health conditions is a very valuable aspect. The result allows for the recommendation of more comprehensive policy making for people who are suffering from multiple health conditions. The authors have improved the quality of the manuscript by responding aptly to the comments of reviewers. However, some improvement or explanation is still required for the methodology, statistical analysis, and results section. Abstract: The conclusion needs some improvement. “Our findings indicate that individuals with chronic health ….. More research is required and also the government should plan on taking care of those patients.” Suggestion: “Our findings indicate that individuals with chronic health ...... More research is required and also the government should plan policies for patients with multiple health conditions.” Methods: Outcome measure: Please correct and update the description of the scoring method for MOS 36-item health-related survey. Therefore, the replication of the method will be authentic and easy. “The 36 items reflect …….., where 100 is defined as perfect health less, and any score less than 100 is defined as poor health.” Suggestion: I am sharing the description along with the citation. The scoring is from 0-100. Higher scores indicate better health status, whereas a low score presents poor health. The mean score of 50 has been considered as a cutoff score for all scales 1 . Statistical Analysis: Suggestion : In Table 1 add a column presenting the calculation of Chi-square. Add a source for socioeconomic slabs in the footnote of Table 1. Authors are reporting that “Quantitative variables were evaluated using Student’s t-test, and quantitative variables without normal distribution were measured using the Mann-Whitney U test.” However, table 2 does not present the student t-test and Mann-Whitney U test explicitly. Suggestion : Provide an SD column for both groups, remove the difference column, and add a column for 't' or 'U' before the P value. Results: Suggestion : As researchers, it is wise to report the results in a more precise manner. According to the standardized scoring categories of DASS, mean scores of anxiety and stress of group A fall at an extremely severe level, whereas depression scores are falling in the range of severity levels. The relevant categories of DASS can be discussed in the result description for group B. It will strengthen the study findings. As in the normal population mean score of depression and anxiety is falling within the mild level. For more details, check scoring categories . Discussion: Suggestion : There is another very interesting result related QoL that needs to be discussed. The highest mean score in group A is in the physical functioning (PF) domain. As all the participants were receiving physiotherapy that could be one of the reasons. Authors can address it better. The lowest mean in both of the groups can be seen in the Role of the limitation-physical health (RL-PH) domain. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Partly If applicable, is the statistical analysis and its interpretation appropriate? Partly Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes References 1. Ware JE: SF-36 health survey update. Spine (Phila Pa 1976) . 2000; 25 (24): 3130-9 PubMed Abstract | Publisher Full Text Competing Interests No competing interests were disclosed. Reviewer Expertise Clinical Psychology, Health Psychology, Personality Psychology, Mental Illness, Neuropsychology, Organizational Behavior I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. reply Respond to this report Responses (0) Zaidi U. Peer Review Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.80174.r167559) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/9-718/v2#referee-response-167559 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2021 Shuja K. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 08 Apr 2021 | for Version 1 Kanwar Hamza Shuja , National Institute of Psychology (NIP), Quaid-I-Azam University (New Campus), Islamabad, Pakistan; Capital University of Science and Technology (CUST), Islamabad, Pakistan 0 Views copyright © 2021 Shuja K. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Not Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants were inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Third the instruments used are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Fourth it would would be nice if the authors can add limitations and recommendations heading before conclusion. Thank you and good luck. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Partly If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests No competing interests were disclosed. Reviewer Expertise Public Health, Criminal Psychology, Clinical Psychology. I confirm that I have read this submission and believe that I have an appropriate level of expertise to state that I do not consider it to be of an acceptable scientific standard, for reasons outlined above. reply Respond to this report Responses (1) Author Response 07 Sep 2022 Ramesh Patra, Department of Physiotherapy, Lovely Professional University, Jalandhar, 144001, India First, we would like to thank the honourable reviewers and editor for their constructive criticisms and suggestive comments, which were of great help in improving the quality and clarity of the current manuscript. We have read each reviewer’s comments carefully and, accordingly, made utmost efforts to address each comment point-by-point. We much appreciate the reviewer’s time, effort, and detailed explanations. We believe that the revised version of our manuscript is now more focused, scientific, understandable, and better arranged. All changes are highlighted with red color. Reviewer Comment: Query 1: Firstly thank you for giving me the chance for reviewing the article. It's a well written article though there are places where some sentences needs to be rewritten and checked for grammar. Response: Thank you for your valuable comments. We have modified the text with proper grammar usage as per your suggestions. Query 2: However, my biggest concern with this article is regarding its sample size. My first question is how did authors come up with a sample size of 50? Did they selected it themselves or what was the reason behind it or did they used sampling size calculator. Because a sample of 50 is too low for concluding this study. Response: The total sample taken was 100. We have calculated the sample size using G power software 3.1 which was found to be around 51 (95% confidence interval, power of the study was 80% where the effect size was considered as 0.5). The sample size calculation has been added in the revised manuscript under the method section. Query 3: Secondly, again with the sample but this time inclusion criteria for the group B was not set by the authors. Having no inclusion criteria could lead to potentially adding participants who may also be medically ill, or were these participants inquired prior during recruitment if they are medically sound. And if they were asked that would have become their inclusion criteria. But unfortunately, I was unable to find any such thing in demographic information. Response: As suggested, we have included the inclusion criteria for Group B. Query 4: Third, the instruments used, are for measuring psychological variables in general. What I mean by this is that nowhere was I able to find anything where the participants were asked their thoughts on Covid-19 or its effect on them. Now depression, stress or anxiety could be potentially due to multiple factors same with the reasons for disturbed quality of life or sleep. The authors should have added some questions in demographic which could help the participants and the readers to know that the findings here are actually due to Covid-19 and not due to any external factor. Response: We have used the following tools to measure all the three measure outcomes. DASS-21 tool was used to measure the mental health. PSQI was used to measure sleep quality. MOS-36 was used to measure the health-related QoL. We have mentioned the tools in the methodology section and also given references. Query 5: Fourth it would be nice if the authors can add limitations and recommendations heading before conclusion. Response: We have included the limitations and recommendations as per your suggestions. View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Shuja KH. Peer Review Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.26834.r82045) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/9-718/v1#referee-response-82045 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2020 Koley S. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 13 Nov 2020 | for Version 1 Shyamal Koley , Department of Physiotherapy, Guru Nanak Dev University, Amritsar, India 0 Views copyright © 2020 Koley S. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions The Abstract, Introduction, Methods, Results, & Discussion Portions of the article are written nicely. The only correction needed is in Acknowledgments where " The author would......" should be written as " The authors would......". References portion are written as per the style of the journal and adequate and expressive. The article is timely written and carries sufficient applicability. Detailed Report: COVID-19 is a serious global pandemic which affects physical, mental, social and societal aspects of individuals of all strata of the society. The present study attempted justly in this regard. It is a very recent complication, thus not much literature would be available. Considering the above fact, the literature cited in the article was justified. It was quite difficult to collect the samples in the time of Lockdown prevailed then nationwide. Still the work would be considered as technically sound. In such type of study, the controls are not necessarily required, pre- and post-conditions may work. The methods and analyses were sound with proper replicability. Though the sample size was small (n=100), statistical analyses (using Chi-square test, Student’s t-test and Man-Whitney U test) were appropriate. The conclusion drawn in the study was adequately supported by the results. Small sample size was one of the limitations of the study. Is the work clearly and accurately presented and does it cite the current literature? Yes Is the study design appropriate and is the work technically sound? Yes Are sufficient details of methods and analysis provided to allow replication by others? Yes If applicable, is the statistical analysis and its interpretation appropriate? Yes Are all the source data underlying the results available to ensure full reproducibility? Yes Are the conclusions drawn adequately supported by the results? Yes Competing Interests No competing interests were disclosed. Reviewer Expertise Kinanthropometry, Biomechanics, Public Health & Lectinology. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (1) Author Response 13 Nov 2020 Ramesh Patra, Department of Physiotherapy, Lovely Professional University, Jalandhar, 144001, India Thank You so much for your Valuable response and comments. View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Koley S. Peer Review Report For: Mental health, sleep quality and quality of life in individuals with and without multiple health conditions during home quarantine in India due to the COVID-19 pandemic: a cross-sectional study [version 3; peer review: 1 approved, 2 approved with reservations, 1 not approved] . F1000Research 2024, 9 :718 ( https://doi.org/10.5256/f1000research.26834.r73792) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/9-718/v1#referee-response-73792 Alongside their report, reviewers assign a status to the article: Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. 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