Associations Between Physical Activity and Cognitive Function, Daily Physical Function in Chinese With Heart Disease: A Cross-Sectional Study

Abstract Background: To investigate the associations between different dimensions (intensity, frequency, duration, volume, metabolic equivalent) of physical activity (PA) and cognitive function, daily physical function in Chinese with heart disease. Methods: This study included 2792 individuals from the China Health and Retirement Longitudinal Study (CHARLS) conducted in 2015. PA was divided into vigorous PA (VPA), moderate PA (MPA), and light PA (LPA). Linear regression models and binary logistic regression models were established to assess the associations be-tween indicators respectively. Results: Compared with taking no PA, MPA and VPA with a frequency of 6-7 d/w had lower risks of impaired daily physical function (OR=0.47, 95%CI: 0.25, 0.91; OR= 0.57, 95%CI: 0.37, 0.88) and higher cognitive function scores (β=1.22, 95%CI: 0.42, 2.03; β=1.08, 95%CI: 0.43, 1.73), while VPA of 3-5 d/w had lower cognitive function scores (β=-1.96, 95%CI: -3.51, -0.40). LPA with a duration of 30-119 min/d had lower risks of impaired daily physical function (OR=0.59, 95%CI: 0.36, 0.97). MPA and VPA of 30-119 min/d had higher cognitive function scores (β=1.43, 95%CI: 0.49, 2.37; β=1.30, 95%CI: -0.56, 2.06). Lower cognitive function scores in volume of ≥ 300 min/w. (β=-1.18, 95%CI: -2.14, -0.23). 1800-8999 METs had lower risks of impaired daily physical function and higher cognitive function scores. 1800-2999 METs had lowest risks of impaired daily physical function and highest cognitive function scores. (OR=0.18, 95%CI: 0.04, 0.75; β=2.94, 95%CI: 1.67, 4.21). Conclusions: This study found that VPA are associated with lower cognition, MPA and LPA are beneficial to cognition and daily physical function.Trial registration: IRB00001052-11015.