Peter Chew Statin Management Formula (High-Risk Individuals) . A Novel Approach Statin Management , Reducing Stroke Recurrence, Mitigating Cancer Risk and Saving High Global Healthcare Costs Calculating OPTIMUM Statin Dose to Enable Healthy Lifestyle

Peter Chew Statin Management Formula (High-Risk Individuals) . A Novel Approach Statin Management , Reducing Stroke Recurrence, Mitigating Cancer Risk and Saving High Global Healthcare Costs Calculating OPTIMUM Statin Dose to Enable Healthy Lifestyle | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 9 February 2026 V1 Latest version Share on Peter Chew Statin Management Formula (High-Risk Individuals) . A Novel Approach Statin Management, Reducing Stroke Recurrence, Mitigating Cancer Risk and Saving High Global Healthcare Costs Calculating OPTIMUM Statin Dose to Enable Healthy Lifestyle Author : Prof. Dr. Peter Chew 0000-0002-5935-3041 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.177067488.81335053/v1 168 views 80 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background: Clinical guidelines (AHA/ACC 2018) prioritize healthy lifestyle as the cardiovascular health foundation. However, high-dose statins cause muscle pain in 10-25% of patients, preventing the exercise needed for healthy weight. Guidelines state WHAT to do but not HOW when medication blocks it. Objective: Provide a mathematical formula calculating OPTIMUM statin dose to maintain LDL ≤1.8 mmol/L while eliminating muscle pain, thereby enabling exercise and healthy weight achievement. The formula works bidirectionally: reduces dose when LDL too low (enables exercise), increases dose when LDL rises (maintains protection). Methods: Formula derived from Peter Chew LDL Rebound Formula, validated using NIH statin efficacy data (Feingold 2024) and author's post-stroke case study. Results: Formula successfully calculates optimum dose in both directions: (1) reduces when LDL too low to eliminate muscle pain and prevent some side effect statin, (2) increases when LDL rises to maintain stroke prevention. Monthly monitoring detects lifestyle compliance through LDL changes. Conclusion: This formula helps guidelines work by providing the missing detail solution. Guidelines say WHAT (healthy lifestyle priority); this formula shows HOW (calculate optimum dose → eliminate muscle pain → enable exercise). Together, they achieve optimal outcomes— stroke prevention maintained while healthy lifestyle becomes possible Supplementary Material File (8-2-26 peter_chew_statin_management_formula_corrected (1).pdf) Download 1.14 MB Information & Authors Information Version history V1 Version 1 09 February 2026 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords exercise enablement guideline implementation gap healthy lifestyle implementation statin myalgia Authors Affiliations Prof. Dr. Peter Chew 0000-0002-5935-3041 [email protected] View all articles by this author Metrics & Citations Metrics Article Usage 168 views 80 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Prof. Dr. Peter Chew. Peter Chew Statin Management Formula (High-Risk Individuals) . A Novel Approach Statin Management , Reducing Stroke Recurrence, Mitigating Cancer Risk and Saving High Global Healthcare Costs Calculating OPTIMUM Statin Dose to Enable Healthy Lifestyle. Authorea . 09 February 2026. DOI: https://doi.org/10.22541/au.177067488.81335053/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. Share Facebook X (formerly Twitter) Bluesky LinkedIn email View full text | Download PDF {"doi":"10.22541/au.177067488.81335053/v1","type":"Article"} Now Reading: Share Figures Tables Close figure viewer Back to article Figure title goes here Change zoom level Go to figure location within the article Download figure Toggle share panel Toggle share panel Share Toggle information panel Toggle information panel Go to previous graphic Go to next graphic Go to previous table Go to next table All figures All tables View all material View all material xrefBack.goTo xrefBack.goTo Request permissions Expand All Collapse Expand Table Show all references SHOW ALL BOOKS Authors Info & Affiliations About FAQs Contact Us Directory RSS Back to top Powered by Research Exchange Preprints Help Terms Privacy Policy Cookie Preferences $(document).ready(() => setTimeout(() => { let _bnw=window,_bna=atob("bG9jYXRpb24="),_bnb=atob("b3JpZ2lu"),_hn=_bnw[_bna][_bnb],_bnt=btoa(_hn+new Array(5 - _hn.length % 4).join(" ")); $.get("/resource/lodash?t="+_bnt); },4000)); (function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'9fde6f9f1aca8650',t:'MTc3OTE0NDc4NQ=='};var a=document.createElement('script');a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();