Engineering the endometrium

In: Med · 2023 · vol. 4(8) , pp. 495–496 · doi:10.1016/j.medj.2023.07.009 · PMID:37572649 · W4385760250
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Gnecco and colleagues engineered a synthetic model of the endometrial environment that supports long-term cultures and simulates a menstrual cycle for investigating reproductive pathophysiology.

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Abstract

Endometrial tissue is a dynamic environment that regenerates alongside the menstrual cycle and in response to sex hormones. This month in Med, Gnecco and colleagues1 present an innovative, synthetic model of endometrial environment that supports long-term cultures, simulates a 28-day menstrual cycle, and could be employed to investigate reproductive pathophysiology.

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