PYRIDYLPHENOL COMPOUND AND USE THEREOF

Discloses is a compound which has a metastin receptor antagonistic activityand is useful for the prevention/treatment of hormone-dependent cancer, benignprostatomegaly, endometriosis, precocious puberty, hysteromyoma or the like.A compound represented by the formula below or a salt or prodrug thereof; and apharmaceutical comprising the compound, salt or prodrug. [Chemical formula]wherein the ring A represents a 5- to 8-membered homocyclic or heterocyclic ringwhich may further have a substituent other than the group: -X-R1 whereX represents a bond or a spacer and R1 represents an amino group whichmay have a substituent or a nitrogenated heterocyclic ring group which may havea substituent; the ring B represents a benzene ring which may have a substituent;R2 represents a homocyclic or heterocyclic ring group which may havea substituent; and R3 and R4 independently represent a hydrogenatom, a cyano group, an acyl group or a hydrocarbon group which may have a substituent.