Successful treatment with bortezomib for POEMS syndrome, overcoming complicated severe heart block
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Abstract
Cardiac bradyarrhythmia and conduction disorder may be rare, but recurrent adverse events caused by bortezomib. Here we report a case with POEMS syndrome presenting severe heart block after bortezomib plus dexamethasone therapy. After permanent pacemaker implantation, bortezomib was restarted and maintained, resulting in sustained complete response for POEMS syndrome.
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- last seen: 2026-05-19T01:45:01.086888+00:00