Barriers in Enabler for Hospitals to Control Hospital- Acquired Infections in India – a Systematic Literature Review

Abstract Hospital-acquired infections (HAIs) have a substantial impact on patient morbidity, mortality, and healthcare expenditures. They represent a major challenge to global healthcare systems. The prevalence of HAIs is very high in India due to the country's unique issues regarding healthcare infrastructure and infection control methods. With the help of this comprehensive evaluation of the literature, hospitals in India should be able to better manage healthcare-associated infections (HAIs). Included were seven investigations that were carried out in India between 2020 and 2022 and covered a range of geographic areas and healthcare settings. Antibiotic resistance is emphasized in the study as a primary obstacle, underscoring the pressing need for novel therapeutic approaches and infection control measures. Colistin is a possible enabler that shows promise in combating microbes resistant to many drugs. The significance of thorough infection control methods, the difficulties experienced by patient populations, such as newborns and patients with liver illness, and the promise of natural remedies such phytochemicals are some other important findings. The consequences for healthcare policy and practice highlight how critical it is to fortify antibiotic stewardship initiatives and execute evidence-based interventions that are customized for regional settings. Even though this evaluation offers insightful information, more investigation is necessary to fully comprehend the intricate variables affecting HAI control in India and to create more effective preventative and treatment plans.