Larotrectinib in a NTRK-rearranged soft tissue sarcoma in the neoadjuvant setting: a case report.
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Abstract
NTRK gene-fusions are rare but can occur in diverse cancers. The NTRK inhibitor larotrectinib is newly approved by the FDA. This paper reports the first case of a man with a NTRK-rearranged soft tissue sarcoma treated with larotrectinib in the neoadjuvant setting, in Belgium, to avoid limb amputation.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00