Preliminary Research on the Role of Rho Family RhoA,RhoB,RhoC mRNA Expression in Endometriosis

In: Zhongguo shiyan fangjixue zazhi · 2013 · W2373603511
article OA: closed CC0 ⤵ 1 in-corpus citation
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Quantified RT-PCR detected markedly lower RhoA and RhoC mRNA expression in endometriosis compared to normal endometrium, suggesting a potential role for their reduced expression in the disease.

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Abstract

Objective:To detect Rho family(RhoA,RhoB,RhoC) mRNA expression and study the role of Rho family in endometriosis.Method: Quantified RT-PCR technique was used in the detection.Result: RhoA and RhoC mRNA expression in endometriosis was lower than that in normal endometrium markedly(P0.05,vs normal).RhoB mRNA expression didn't show any distinction between the groups.Conclusion: Endometriosis may be related to the low expression of RhoA and RhoC.

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endometriosis

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