Analysis on the quality of life of patients with moderate to severe endometriosis treated with different drugs after surgery

Objective:To explore the quality of life(QOL) of patients with moderate to severe endometriosis treated with different drugs after surgery. Methods:96 patients with moderate to severe endometriosis were divided into group A and group B randomly,47 patients in group A were treated with adjuvant gonadotropin-releasing hormone agonist(GnRH-a) after surgery,49 patients in group B were treated with adjuvant gestrinone after surgery,the patients in the two groups were followed up at one week before surgery,1,3 and 6 months after surgery,then QOL scores were conducted,the QOLs in the two groups were analyzed. Results:There was no significant difference in remission rate and recurrence rate between the two groups;the incidence of adverse reactions in group A was significantly higher than that in group B(P0.05).QOLs at 3 and 6 months after surgery in group B were significantly higher than those in group A. Conclusion:There is no significant difference in short-term curative effect(remission rate and recurrence rate) between adjuvant GnRH-a and adjuvant gestrinone after surgery in treatment of moderate to severe endometriosis,the curative effect of the latter is superior to that of the former in terms of improvement of QOL.