Abdominal mouse in a patient with endometriosis post GnRH therapy

In: Indian Journal of Gynecological Endoscopy · 2024 · vol. 1(1) , pp. 63–64 · doi:10.4103/ijge.ijge_2_24 · W4401907742
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A 26-year-old woman with endometriosis treated with three cycles of GnRH analogs presented with pelvic pain and was found to have peritoneal loose bodies during laparoscopy.

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This case report describes a 26-year-old woman with pelvic pain and dysmenorrhea who was found to have bilateral endometriosis cysts on ultrasonography. After undergoing three cycles of GnRH analog therapy, the patient underwent laparoscopy which revealed the presence of peritoneal loose bodies, also known as abdominal mice, in the pelvis. The authors note that while these fatty loose bodies are typically asymptomatic incidental findings resulting from fat necrosis or infarction, their occurrence in this context was documented following hormonal treatment for endometriosis. This paper is centrally about endometriosis — specifically describing an incidental finding of peritoneal loose bodies observed during surgical management of the condition.

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Abstract

Abstract A 26-year-old unmarried woman complained of pelvic pain and dysmenorrhea. On pelvic examination, her cervix was pulled up with bilateral forniceal tenderness. On ultrasonography, her left ovary showed two 4 cm × 4 cm endometriosis cysts and a negative sliding sign. She was placed on three cycles of GnRH analogs and on laparoscopy showed the presence of peritoneal loose bodies in the pelvis [Figures 1 and 2].
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Introduction

Peritoneal loose bodies (PLBs) are uncommon incidental findings seen on laparoscopy or exploration in a range of patients. The reasons for the occurrence of these entities and their origin are many. They may even be seen following GnRH therapy in endometriosis, as in our case. CASE REPORT A 26-year-old unmarried woman (body mass index: 29 kg/m2) complained of pelvic pain and dysmenorrhea. On pelvic examination, her cervix was pulled up with bilateral forniceal tenderness. On ultrasonography, her left ovary showed two 4 cm × 4 cm endometriosis cysts and a negative sliding sign. She was placed on three cycles of GnRH analogs and on laparoscopy showed the presence of PLBs in the pelvis [Figures 1 and 2].

Discussion

PLBs are also known as abdominal mice. They may be from a range of sources, including calcified myomas or necrotic fatty tissue from the mesentery.[,] These are usually small, measuring 0.5–2 cm, but can, in some cases, be larger, about 5 cm in size. They are usually asymptomatic. Microscopy of these fatty loose bodies demonstrates dystrophic calcifications and necrosis. PLBs are frequently located in the pericolonic region or near the adnexa anteriorly. The differential diagnosis can be late-stage epiploic appendagitis, mesenteric panniculitis, or omental infarction. More often, they go unnoticed on ultrasonography and are only seen on laparoscopy or laparotomy. Epiploic appendagitis that has undergone fat necrosis and detachment is a common cause based on a literature search.[,] It results due to infarction and detachment of epiploic appendages. This entity rarely needs surgical intervention. To conclude, we demonstrate the occurrence of PLBs or abdominal mice in a patient with endometriosis after GnRH therapy. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that her name and initials will not be published and due efforts will be made to conceal her identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.

References

1. Gayer G, Petrovitch I, Jeffrey RB. Foreign objects encountered in the abdominal cavity at CT. Radiographics 2011;31:409–28.2. Ghahremani GG, White EM, Hoff FL, Gore RM, Miller JW, Christ ML. Appendices epiploicae of the colon:Radiologic and pathologic features. Radiographics 1992;12:59–77.3. Mayfield J, Schammel C, Yurko Y, Schammel DP, Devane AM. Peritoneal loose bodies and the differentiation of fatty abdominal and pelvic lesions. Radiol Case Rep 2020;15:1506–11.4. Wen Y, Shang MJ, Ma YQ, Fang SH, Chen Y. Peritoneal loose body presenting as a hepatic mass:A case report and review of the literature. Open Med (Wars) 2021;16:1356–63.

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endometriosisdysmenorrhea

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