Combining Influenza and COVID-19 Booster Vaccination Strategy: A Systematic Review and Meta-Analysis

In this systematic review and meta-analysis, a synthesis of the findings and summary of a total of 30 research articles based on the topic, ‘combining influenza and COVID-19 booster vaccination strategy’ was undertaken. The research articles were identified from three databases, namely, PubMed, Cochran Library, and Google Scholar, using specific keywords and inclusion criteria. However, peer-reviewed research articles not published in English were excluded from the systematic review and meta-analysis. The average risk ratio of the included articles was 0.78% based on a 95% CI. On the other hand, the heterogeneity between such studies was I2, = 3the 5% while statistical significance of their findings occurred at p < 0.05p-value average p value of the included research studies was p =,0.62 which implies that the null hypothesis was not rejected in almost all the studies. A synthesis of the chosen research articles revealed that when influenza and COVID-19 booster vaccines are combined, there is potential for an increase in the latter's uptake, mainly because many populations have already been accustomed to taking influenza vaccines annually. In this way, through such findings, medical health experts can make informed decisions to increase the population's willingness to receive the COVID-19 booster vaccines.Funding Information: None.Declaration of Interests: None.