The effect of naloxone on episodic LH secretion during danazol treatment

U. Cirkel, J. P. Hanker, Dieter Meschede, H. Schneider
In: Acta Endocrinologica · 1987 · vol. 116(3_Suppl) , pp. S198 · doi:10.1530/acta.0.114s198 · W2094463567
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study investigated whether danazol's suppression of gonadotropins during endometriosis treatment affects episodic LH secretion and if opiates are involved in this mechanism.

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Abstract

Danazol has been extensively utilized in the treatment of endometriosis. The therapeutic effect of this ethisterone derivative is partly attributed to a suppression of gonadotropin secretion. It was the aim of this study to examine whether danazol - similar to other gestagenic compounds - has an impact on the pattern of pulsatile LH secretion and whether opiates are involved in such mechanisms.

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endometriosis

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last seen: 2026-05-10T10:37:40.910869+00:00
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