Expression and significance of KISS-1 in ectopic endometrium in patients with endometriosis

Peng Lai-qin, Rui-ping Liao, Lanying Zhang, Fengying Huang, Jiang‐Tao Chen
In: Zhongguo jiceng yiyao · 2008 · vol. 15(06) , pp. 905–906 · doi:10.3760/cma.j.issn.1008-6706.2008.06.013 · W3030683442
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Abstract

Objective To study the expression of KISS-1 in normal endometrium and in ectopic endometri-um patients with endometriosis. Methods The expression of KISS-1 in 55 cases of normal endometrium as well in 46 cases of ectopie endometriurn with endometriosis were detected by immunohistochemicai EliVision plus method. Results The positive expression rates of KISS-1 in ectopic endometriotic tissues and in normal endometri-urn were 30.43 % and 63.64 % respectively ,and the positive expression rates in ectopic endometriotic tissues signifi-cantly lower than those in the normal endometrium( P< 0.01, P < 0.05). Conclusion The decreased expression of KISS-1 may be related to the mechanism of endometriosis. Key words: Endometriosis; Genes,KISS-1; Immunohistochemistry

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