HPA axis reactivity in chronic pelvic pain: association with depression

Katja Wingenfeld, Dirk H. Hellhammer, Iris Schmidt, Dieter Wagner, Gunther Meinlschmidt, Christine Heim
In: Journal of Psychosomatic Obstetrics & Gynecology · 2009 · pp. 1–5 · doi:10.1080/01674820903254732 · W4255391437
article OA: closed CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-12 ⓘ

This paper investigated the relationship between the hypothalamic-pituitary-adrenal (HPA) axis and chronic pelvic pain, specifically examining its association with depression.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 · read from full text ⓘ

The paper investigates whether chronic pelvic pain is associated with altered hypothalamic–pituitary–adrenal (HPA) axis reactivity and examines a relationship with depression, using a human study design that likely measures stress-axis responsiveness alongside depressive symptoms. It reports an association between HPA axis reactivity in individuals with chronic pelvic pain and depression. A major caveat, stated in the paper’s context, is that the provided text does not include the specific methods, effect sizes, or limitations, so the strength of causal inference and study design details cannot be evaluated from the excerpt alone. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Condition tags

chronic_pelvic_pain

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (1)

Cited by (1)

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openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK