Methods and means of Fourier-Stokes polarimetry and the spatial-frequency filtering of phase anisotropy manifestations in endometriosis diagnostics

А. Г. Ушенко, Olexander V. Dubolazov, V. A. Ushenko, Yuriy Ushenko, M. Y. Sakhnovskiy, O. G. Prydiy, I. I. Lakusta, O. Yu. Novakovskaya, С.Р. Меленко
In: SPIE Proceedings · 2016 · vol. 10010 , pp. 100100N · doi:10.1117/12.2243149 · W2562408271
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Abstract

This research presents investigation results of diagnostic efficiency of a new azimuthally stable Mueller-matrix method of laser autofluorescence coordinate distributions analysis of dried polycrystalline films of uterine cavity peritoneal fluid. A new model of generalized optical anisotropy of biological tissues protein networks is proposed in order to define the processes of laser autofluorescence. The influence of complex mechanisms of both phase anisotropy (linear birefringence and optical activity) and linear (circular) dichroism is taken into account. The interconnections between the azimuthally stable Mueller-matrix elements characterizing laser autofluorescence and different mechanisms of optical anisotropy are determined. The statistic analysis of coordinate distributions of such Mueller-matrix rotation invariants is proposed. Thereupon the quantitative criteria (statistic moments of the 1st to the 4th order) of differentiation of dried polycrystalline films of peritoneal fluid – group 1 (healthy donors) and group 2 (uterus endometriosis patients) are estimated.

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endometriosis

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