Особенности изменений кортизола и соматотропоного гормона у детей с Helicobacter pylori-ассоциированным хроническим гастродуоденитом в сочетании с гастроэзофагеальной рефлюксной болезнью

Studies of the level of growth hormone and cortisol in peripheral blood at 154 children aged 8-15 years old, located in the I-III stages of puberty with chronic gastroduodenitis in combination with gastroesophageal reflux disease. In 58 (37,7%) patients the disease was associated with H pylori infection. The proportion of erosive gastroduodenitis in the group Н.pylori-positive patients was 58.6%, which was significantly higher than the share of erosive lesions of the mucous membrane of the gastroduodenal region (37,5%) among Н.pylori-negative patients (p<0.05). It is established that the level of somatotropic hormone was reduced, and the level of cortisol is increased in H pylori-positive seropositive patients compared H pylori positive seronegative and H pylori-negative patients and control group.