New approaches in the treatment of cervical erosion and vaginal atrophy

The therapeutic use of various materials has long been known in medical practice. The use of polymers in dental surgery, eye surgery, heart surgery and other areas today is widespread in most countries. Substances that interact with human cells are called biomaterials. However, many issues of the interaction between human cells and synthesized materials remain unresolved, for example, such as compatibility and degradation in the case of prosthetics. The development of combined materials containing human proteins or cells and complex polymers is a promising industry in the development of medicine. The extracellular matrix (ECM) is an auxiliary substance for each cell of the human body, contains proteins and macromolecules. Substances derived from ECM are now widely used as biomaterials, such as collagen and hyaluronic acid. A large number of studies on the effect of hyaluronic acid on the human body, allowed us to determine its main properties, due to which hyaluronic acid is widely used in the medical, pharmaceutical and cosmetic industries, namely, for its high bioavailability, degradability, and lack of response of the immune system to this compound, as well as for its viscoelasticity. Such properties of hyaluronic acid provide the possibility of its use in obstetric and gynecological practice. Vaginal suppositories with hyaluronic acid and medicinal plants are becoming popular because they are safe and effective, which doctors and patients pay attention to. The preparations Gial-Eroz and Gial-Meno, which are presented in the form of suppositories, are the optimal dosage form for intravaginal use. The use of Gial-Eroz and Gial-Meno drugs, which have various mechanisms for restoring the vaginal mucosa, can be an effective part of complex therapy in women with cervical erosion and atrophic vaginitis. Key words: cervical erosion, vaginal atrophy, women, hyaluronic acid, vitamins, postmenopausal period, Gial-Eroz, Gial-Meno.