Global trends of Helicobacter pylori biofilm research in the past two decades: A bibliometric study

Background: Helicobacter pylori biofilm formation is a key factor of refractory helicobacter pylori infection. This study aimed to access the research trends of helicobacter pylori biofilm. Methods: : Publications from 1998 to 2022 were retrieved from the Web of Science Core Collection database. Different kinds of software, EXCEL, VOSviewer, and the online bibliometric analysis platform were used to evaluate and visualize the bibliometric data. Results: : A total of 154 publications were finally identified, and the annual number of publications showed a rising trend. The China made the greatest contributions to this research field, while the journal of Helicobacter was the most productive journal. Grande rossella published the most papers, and the most productive institution was G dannunzio University. Co-occurrence network maps revealed that the keyword of “Helicobacter pylori” ranked first in research field, and the keyword of “biofilm formation” and “in vitro” began to appear in the past 3 to 5 years. Conclusion: The annual number of publications on helicobacter pylori biofilm have grown steadily in the past two decades and will continue to grow. Future research hot spots will domain in the establishment of helicobacter pylori biofilm in vitro model and mechanism of helicobacter pylori biofilm formation.