Хронический эндометрит, эндокринная функция яичников и рецептивность эндометрия: есть ли связь?

The purpose is to study clinical and morphological features and receptivity of endometrium in patients with chronic endometritis (CE) and various endocrine function of the ovaries. 161 patients were examined. The first group comprised 43 patients with CE and normal ovulatory menstrual cycle, II group 80 women with CE and insufficient luteal phase, III group 38 patients with CE and anovulatory ovarian dysfunction. Control group 20 gynecologicaly healthy women. It was found that patients with CE have marked structural changes and endometrial receptivity disorder presented as damaged surface epithelium, maturation pinopody violations at the time of the window of implantation, overexpression of ER, PR reduction in the stroma and expression of LIF. The more these changes are expressed, the more secretory transformation of the endometrium and ovarian endocrine function are destroyed, and these changes may underlie the impaired reproductive function in patients with CE.