MALIGNANT TUMORS OF THE APPENDIX: CLINICAL AND MORPHOLOGICAL ANALYSIS OF CASES FROM THE PRACTICE

Mykhailo S Myroshnychenko, Olena O Dyadyk, Nataliia V Kapustnyk, Yuliia Ya Fedulenkova, I. V. Borzenkova, Iryna V Borzenkova, Olha M Astapieva, Larisa I Selivanova, Valentyna V Zakharenko, Olena Yu Lytvynenko, Dmytro V Molodan, Olga I Paskevych, Kristina Od Akritova, Bohdan I Melnik, Vladyslava M Bobrova
Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2021 · vol. 74(5) , pp. 1277–1280 · doi:10.36740/wlek202105143 · PMID:34090305 · W3168359709
article OA: bronze CC0
🔓 Open OA copy View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

This clinical and morphological analysis of two appendix cancer cases, adenocarcinoma and neuroendocrine tumor, highlights that these malignant tumors manifested as acute appendicitis and were only identified through surgical material examination.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

The authors have analyzed medical histories of two patients, treated in health care facilities of Kharkiv region from 2008 to 2020. These patients underwent urgent appendectomy, given the existing clinic of acute appendicitis. Morphological examination of the surgical material allowed us to diagnose adenocarcinoma in one case, and neuroendocrine tumor in combination with endometriosis in the other case. Morphological examination of the surgical material in the first case revealed a moderately differentiated adenocarcinoma and diffuse neutrophilic infiltration in all layers of the appendix, and in the second case - a well-differentiated neuroendocrine tumor (G3), combined with the signs of phlegmonous-ulcerative appendicitis and loci of endometriosis. In both cases, there were no specific for the oncological process anamnestic and clinical-instrumental data, and these tumors were manifested by the clinic of acute appendicitis. Only morphological examination of the surgical material allowed identifying the pathological process. Clinical and morphological analysis of cases from the practice of malignant tumors of the appendix (neuroendocrine tumor and adenocarcinoma) will be useful and interesting for the medical community and should stimulate cancer vigilance in physicians.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Adenocarcinoma Appendiceal Neoplasms Appendiceal Neoplasms Appendicitis Appendicitis Appendicitis Appendix Appendix Appendectomy Female Humans

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cites (1)

References (17)

Source provenance

europepmc
last seen: 2026-06-16T06:07:01.518242+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:24:37.768885+00:00
License: CC0 · commercial use OK