Perioperative management of malignant hyperthermia during general anesthesia: A case series Running title: Malignant hyperthermia under anesthesia

Malignant hyperthermia (MH) is a lethal complication associated with general anesthesia characterized by sudden onset, rapid progression, and high mortality. Adequate preoperative assessment, attention to MH susceptibility, early identification of MH response, timely rescue, early use of dantrolene, and attention during cardiopulmonary bypass are necessary for comprehensive MH treatment.