P10.07: Hormonal treatment effect on dysmenorrhea in women with and without endometriosis

The aim of this study was to assess the effect of hormonal treatment on patients' symptoms in women with dysmenorrhea depending on ultrasound findings. Women with dysmenorrhea and suspected endometriosis underwent transvaginal ultrasound examination in 2014-2017 at the Ultrasound unit in Women's clinic. Ultrasound examinations were performed using GE E8 ultrasound machine according to standardised endometriosis examination protocol. Women were asked about their symptoms (dysmenorrhoea, chronic pelvic pain, dyspareunia, dyschezia, dysuria), hormonal treatment. Severity of symptoms was assessed using visual analogue scale (VAS) and was classified as mild, moderate or severe. The severity of symptoms with and without hormonal treatment was compared between women with detected endometriosis at ultrasound examination and normal ultrasound findings. Out of 373 women included, 178 (48%) women had normal ultrasound findings, 114 (31%) women had endometriosis at any of the possible location and 81 (22%) women had other pathological findings. Women with endometriosis reported lower VAS (median (range)) for dysmenorrhea than women with normal ultrasound findings both in the group of women with and without hormonal treatment (50 (8–98) vs. 62 (7–100), p = 0.024 and 79 (17–100) vs. 86 (15–100), p = 0.015). VAS for dysmenorrhea was lower when woman was taking hormonal treatment than without in both subgroup with normal ultrasound findings and subgroup with endometriosis (p = 0.001, p < 0.001). Endometriosis was more often found in women with dysmenorrhea and mild other symptoms than in women with dysmenorrhea and moderate or severe other symptoms (25/52 (48%) vs. 89/321 (28%), p = 0.005). Women with detected endometriosis at ultrasound examination had less severe dysmenorrhea than women with normal ultrasound findings. Hormonal treatment reduces the dysmenorrhea in all women. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.