Faculty Opinions recommendation of Treatment of endometriosis-related chronic pelvic pain with Ulipristal Acetate and associated endometrial changes.

In: Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2019 · doi:10.3410/f.735134387.793557767 · W4251392956
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This faculty opinion recommends ulipristal acetate for treating endometriosis-related chronic pelvic pain, noting that aberrant progesterone signaling is a shared pathway in fibroids and endometriosis.

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Abstract

Background: Aberrant progesterone signaling has been demonstrated in mechanistic studies to be a shared common pathway in fibroids and endometriosis. Progesterone receptor modulation with the selective progesterone receptor modulator (SPRM) ulipristal may decrease pain associated with endometriosis.

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endometriosischronic_pelvic_pain

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