Factors Associated with Mortality in Hospitalized Older Adults

Background: This study aimed to evaluate mortality risk associated with readily accessible laboratory parameters and underlying conditions in hospitalized older adults. Methods: : This retrospective study included geriatric patients admitted for inpatient care to the internal medicine wards of two major university hospitals in two different regions of Turkey. Data related to the patients were collected by retrospective review of patient charts and electronic records. Survival data were obtained from the Death Reporting System of the Turkish Ministry of Health. Survival after admission at 30 days and 1 year was noted. Results: : The study included 1,465 hospitalized older adults with a median age of 74 years, of whom (51.0%) were women. Of these patients, 115 (7.8%) died within 30 days and 382 (26.1%) died within 12 months. Admission for infectious diseases or palliative support and the presence of malignancy were identified as independent risk factors for both 30-day and 12-month mortality. A 1-unit increase in CCI corresponded to 20% higher odds of both 30-day and 12-month mortality. A 1-unit increase in MPV was associated with 52.5% higher odds of 30-day mortality. A 1-unit increase in CRP was associated with a small but statistically significant 0.6% increase in the odds of 30-day and 12-month mortality. Conclusions: : The results of this study show that CCI, CRP, and NLR were associated with higher mortality both at 30 days and 12 months. A 1-unit increase in MPV was associated with 52.5% higher odds of 30-day mortality