Straightforward convergent access to 2-arylated polysubstituted benzothiazoles
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Abstract
A modular access to 2,4 disubstituted benzothiazoles has been achieved though the intermediacy of 4-bromo-2-iodobenzothiazole. The difference in reactivity of both halogens was advantageously exploited to achieve sequential Suzuki-Miyaura cross-coupling giving access to a range of polyaromatic derivatives featuring a central benzothiazole core.
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- last seen: 2026-05-19T01:45:01.086888+00:00