Effectiveness of Extra Corporeal Removal Methods in the Management of Paraquat Poisoning: A Retrospective Analysis

Paraquat poisoning is a major medical problem in many parts of Asia, Pacific nations, and America. An increased rate of morbidity and mortality is associated with paraquat poisoning due to the absence of a definite antidote. The objective of this study is to assess the effectiveness of various treatment strategies with the outcome in paraquat poisoning. In this study the mean age of 206 patients were 28.14±11.35 years. Majority of the patient population were males (63.6%). Extra Corporeal Removal treatment (ECR) (45.6%) method was given majorly to the patients. Primary outcome analysis with respect to various ECR methods revealed that hemoperfusion (43.9%) showed better results compared to other ECR methods. Secondary outcome such as the ICU days (4.66±3.43), ventilator days (0.63±1.61), and secondary complications (7.6%) was comparatively less in the group treated with hemoperfusion. The treatment analysis revealed ECR of Paraquat by hemoperfusion ensured better clinical outcomes in terms of primary and secondary outcomes.