Effects of combined general anesthesia and epidural block anesthesia on the patients undergoing laparoscopic hysterectomy and its influence on stress response

Objective To investigate the effect of combined general anesthesia and epidural anesthesia on laparoscopic hysterectomy and its effect on the body’s stress response. Methods A total of 110 Patients with total laparoscopic hysterectomy admitted to Binzhou Central Hospital from August 2015 to December 2018 were selected as the subjects of this study. Random number table method was used to divide the patients into two groups, with 55 cases in each group. The study group underwent general anesthesia combined with epidural block anesthesia, and the control group underwent general anesthesia with intravenous inhalation. The effect of combined general anesthesia and epidural anesthesia on stress response in laparoscopic hysterectomy were investigated. Results The heart rate and mean arterial pressure were compared between the two groups at T1(P>0.05). At T2 and T3, the heart rate and mean arterial pressure of the study group were lower than those of the control group (P 0.05), the above indicators were still higher than the level at T1 in the control group (P<0.05); the opening time of eyes, extubation time and recovery time of spontaneous breathing in the study group were significantly shorter than those in the control group (P<0.05). Conclusions General anesthesia and epidural anesthesia combined with laparoscopic hysterectomy are effective and safe, which is beneficial to reducing the stress response of patients. Key words: Laparoscopic hysterectomy; General anesthesia; Epidural block anesthesia; Stress response