Delayed Diagnosis of Thoracic Schwannoma Misinterpreted as Perineural Cyst: A Case Report of Chronic Neuropathic Pain with Favorable Surgical Outcome

Delayed Diagnosis of Thoracic Schwannoma Misinterpreted as Perineural Cyst: A Case Report of Chronic Neuropathic Pain with Favorable Surgical Outcome | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Delayed Diagnosis of Thoracic Schwannoma Misinterpreted as Perineural Cyst: A Case Report of Chronic Neuropathic Pain with Favorable Surgical Outcome Anna Gil, Jakub Wilczek, Barbara Jagiełło-Bajer This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8115414/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: To present a rare case of schwannoma cyst imitating perineural cyst. Case presentation: A 61-year-old woman with 5-year history of thoracolumbar spine pain. MRI T2 in 2019 revealed round extradural lesion at the Th6/Th7. It was misdiagnosed then as Tarlov cyst. In 2024 MRI was retaken and cyst was diagnosed as schwannoma. Later, in that year patient underwent surgical resection. Conclusions: Schwannoma may be misdiagnosed as Tarlov cyst, yet their treatment is significantly different. This is not the first case of such misdiagnose so it is essential to promote this topic and improve overall awareness. Cystic schwannoma Neuropatic Pain Perineural cyst Case Report Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8115414","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":546338778,"identity":"20759f47-d691-4d0b-8330-e89f4f709cdd","order_by":0,"name":"Anna 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A Case Report of Chronic Neuropathic Pain with Favorable Surgical Outcome","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Cystic schwannoma, Neuropatic Pain, Perineural cyst, Case Report","lastPublishedDoi":"10.21203/rs.3.rs-8115414/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8115414/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cem\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e\u003c/em\u003e\u003cem\u003e \u003c/em\u003eTo present a rare case of schwannoma cyst imitating perineural cyst.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eCase presentation:\u003c/strong\u003e\u003c/em\u003e\u003cstrong\u003e \u003c/strong\u003eA 61-year-old woman with 5-year history of thoracolumbar spine pain. MRI T2 in 2019 revealed round extradural lesion at the Th6/Th7. It was misdiagnosed then as Tarlov cyst.\u003cem\u003e \u003c/em\u003eIn 2024 MRI was retaken and cyst was diagnosed as schwannoma. Later, in that year patient underwent surgical resection.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003eConclusions:\u003c/strong\u003e\u003c/em\u003e\u003cem\u003e \u003c/em\u003eSchwannoma may be misdiagnosed as Tarlov cyst, yet their treatment is significantly different. This is not the first case of such misdiagnose so it is essential to promote this topic and improve overall awareness.\u003c/p\u003e","manuscriptTitle":"Delayed Diagnosis of Thoracic Schwannoma Misinterpreted as Perineural Cyst: A Case Report of Chronic Neuropathic Pain with Favorable Surgical Outcome","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-11-20 17:47:02","doi":"10.21203/rs.3.rs-8115414/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"3aff2a83-6cc3-4694-901e-0dec67a708b0","owner":[],"postedDate":"November 20th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-11-22T10:08:44+00:00","versionOfRecord":[],"versionCreatedAt":"2025-11-20 17:47:02","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-8115414","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-8115414","identity":"rs-8115414","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}