Highly-sensitive troponin I is increased in patients with gynecological cancers

Elisa Danese, Montagnana M, Martina Montagnana, Silvia Giudici, Giudici S, Silvia Dei Giudici, Aloe R, Rosalia Aloe, Massimo Franchi, Massimo Piergiuseppe Franchi, Gian Cesare Guidi, Giuseppe Lippi
Clinical biochemistry · 2013 · vol. 46(12) , pp. 1135–1138 · doi:10.1016/j.clinbiochem.2013.04.029 · PMID:23660299 · W2015008052
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This study investigated elevated levels of highly-sensitive troponin I in patients diagnosed with gynecological cancers.

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Abstract

ObjectivesTo investigate troponin I (TnI) in patients with gynecological cancers.MethodsHighly-sensitive (HS) and conventional TnI were measured in 25 patients with untreated ovarian cancer, 25 with endometriosis and 25 with benign masses.ResultsBoth HS and conventional TnI were increase in cancer patients. Values above the cut-off were found in 44% and 16% cancer patients using HS and conventional TnI methods, respectively.ConclusionsCardiac involvement is frequent in patients with gynecological cancers and should be preferably assessed using HS troponin immunoassays.

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MeSH descriptors

Genital Neoplasms, Female Immunoassay Troponin I Adult Female Genital Neoplasms, Female Humans Immunoassay Middle Aged Sensitivity and Specificity Troponin I

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