Presentation and outcome of central serous chorioretinopathy with and without pachychoroid

Abstract BackgroundPresent study compared clinical features and outcome of Central serous chorioretinopathy (CSC) with and without pachychoroid.MethodsIt was a retrospective, longitudinal, record-based study which included eyes with CSC. Patients underwent spectral domain optical coherence tomography and differentiated between pachychoroid and non-pachychoroid groups.Results250 eyes of 250 patients were divided into pachychoroid and non-pachychoroid with 125 eyes in each group. Mean age of patients in pachychoroid and non-pachychoroid groups were 45.7 ± 9.4 years and 47.4 ± 10.2 years respectively. Mean initial best corrected visual acuity(BCVA) was 0.40 ± 0.42 in pachychoroid and 0.39 ± 0.38 in non-pachychoroid group(p = 0.9). Mean final BCVA was 0.37 ± 0.9 in pachychoroid and 0.21 ± 0.33 in non-pachychoroidgroup(p = 0.04).36(28.8%) eyes in pachychoroid and 60(48%) eyes in non-pachychoroid group had spontaneous resoluti on of CSC (p = 0.007). A total of 39(31.2%) eyes in pachychoroid and 13(10.4%) in non-pachychoroid group had recurrent CSC at the end of follow up.ConclusionCSC eyes with pachychoroid had more recurrent episodes and less spontaneous resolution compared to CSC eyes in non-pachychoroid group. Final visual acuity was worse in eyes with CSC and pachychoroid. These findings need to be validated in a larger sample size with prospective study design.