Comparing frequency of women with adenomyosis (n = 2,228) using prescribed psycho- and neuroactive drugs three years before to three years after surgery in different routes of hysterectomy.

Analyze of interaction in proportion of opioid users including hysterectomy procedure and study year (base outcome vaginal hysterectomy and 3 years preoperative). Graph showing point estimate and 95% confidence interval (shadowed area). TLH/RATLH = Laparoscopic/Robotic assisted hysterectomy AH = Abdominal hysterectomy VH = Vaginal hysterectomy. Preop = Before hysterectomy; Postop = After hysterectomy. OR, Odds Ratio; 95% CI, 95% Confidence Interval. a = adjusted for baseline data including all variables from Table 1. (TIF)