[Plasma fibrinogen in female patients with genital cancer and its early stage]
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This study investigated plasma fibrinogen and fibrin monomer complexes in 54 female genital cancer patients and found they depend on tumor extension, with differently degraded fibrinogens present, but fibrinogenolysis did not correlate with tumor stage.
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Abstract
Changes of plasma fibrinogen derivates in 54 female patients suffering from carcinomas of the genital system (36 with cervix carcinoma, 9 with ovarian carcinomas, 7 with carcinomas of the corpus uteri, 1 woman with a vulva and 1 patient with vaginal carcinoma) and 6 females with cervical intraepithelial neoplasia were investigated. It was shown, that the fibrinogen content and the concentration of soluble fibrin monomer complexes in blood plasma depend on the extension of the clinically diagnosed tumor. Furthermore, differently degraded fibrinogens were demonstrated to exist in the blood circulation. The extent of fibrinogenolysis did not correlate with the clinically diagnosed tumor stage.
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- europepmc
- last seen: 2026-06-24T06:10:11.469335+00:00
- pubmed
- last seen: 2026-05-13T22:09:50.790931+00:00
License: public-domain-us
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine