Nitric oxide detection using catalytic properties of CuCo-PTC metal-organic framework

Nitric oxide is one of the atmospheric pollutants and an important gas messenger molecule in the human body, involved in many physiological and pathological processes. Therefore, detecting nitric oxide rapidly and accurately has been one of the popular topics in recent decades. In this study, we synthesized CuCo-PTC MOF materials using a solvothermal method based on the mechanism of triazole ring formation from o-phenylenediamine (OPD) and nitric oxide. The synthesized CuCo-PTC MOF materials show high sensitivity and good selectivity for detecting nitric oxide in vitro and in cell lysates. The results indicate the potential for applying this sensing strategy to detect nitric oxide in the internal environment.