Comparative efficacy of various methods of infertility treatment in patients with external genital endometriosis

N. I. Volkov, Zh. V. Bespalova, P. A. Bazanov, I. V. Volosenok
In: Journal of obstetrics and women's diseases · 2021 · vol. 50(3) , pp. 25–27 · doi:10.17816/jowd95553 · W4200327017
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study compared infertility treatments for endometriosis, finding that combined surgical destruction of foci followed by antigonadotrophic therapy yielded the highest pregnancy rates within 6-8 months post-treatment.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This study evaluated the comparative efficacy of different drug regimens and endoscopic surgical approaches for infertility in 548 infertile women with external genital (endometriosis) disease. The authors report that combined therapy—endoscopic destruction of endometriotic foci followed by antigonadotropic preparations—had distinct advantages, with the highest impregnation frequency occurring during the first 6–8 months and declining to a minimum by 11–12 months. A stated limitation is that the analysis focuses on pregnancy timing and does not detail longer-term outcomes beyond this observation window. This paper is centrally about endometriosis — it compares infertility treatments in patients with external genital endometriosis.

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Abstract

With the aim of comparative examination of efficacy of different drugs and methods of endoscopic surgery in treatment of infertile women with genital endometriosis 548 patients were examined. Distinct advantages of combined treatment were revealed: surgical destruction of endometrial foci at the first stage and administration of antigonadotrophic preparations at the second stage. Maximum frequency of impregnation after such therapy was observed during first 6-8 months. By 11-12 months the index decreased to its minimum. So, it is reasonable to give up passive supervision after 12 months
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Comparative efficacy of various methods of infertility treatment in patients with external genital endometriosis - Authors: Volkov N.I.1, Bespalova Z.V.1, Bazanov P.A.1, Volosenok I.V.1 - Affiliations: - Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences - Issue: Vol 50, No 3 (2001) - Pages: 25-27 - Section: Original study articles - Submitted: 29.12.2021 - Accepted: 29.12.2021 - Published: 30.12.2021 - URL: https://journals.eco-vector.com/jowd/article/view/95553 - DOI: https://doi.org/10.17816/JOWD95553 - ID: 95553 Cite item Abstract With the aim of comparative examination of efficacy of different drugs and methods of endoscopic surgery in treatment of infertile women with genital endometriosis 548 patients were examined. Distinct advantages of combined treatment were revealed: surgical destruction of endometrial foci at the first stage and administration of antigonadotrophic preparations at the second stage. Maximum frequency of impregnation after such therapy was observed during first 6-8 months. By 11-12 months the index decreased to its minimum. So, it is reasonable to give up passive supervision after 12 months Full Text About the authors N. I. Volkov Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences Author for correspondence. Email: [email protected] Russian Federation, Moscow Zh. V. Bespalova Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences Email: [email protected] Russian Federation, Moscow P. A. Bazanov Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences Email: [email protected] Russian Federation, Moscow I. V. Volosenok Scientific Center for Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences Email: [email protected] Russian Federation, Moscow

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