Urinary Metabolites for the Non-Invasive Diagnosis of Endometriosis Phenotypes

Endometriosis is a chronic disease affecting 1 in 7 women in Australia. Currently, there is a delay to diagnosis of 8 to 11 years worldwide with diagnosis relying primarily on invasive laparoscopic surgeries. Thus, the development of non-invasive diagnostic methods is an urgent clinical priority. This thesis applied nuclear magnetic resonance (NMR) and liquid chromatography–mass spectrometry (LC-MS) to investigate urinary metabolite signatures associated with endometriosis.