Endometriosis-associated ovarian cancer. Presentation of a case report and review of the literature.

Vasilios Pergialiotis, V Pergialiotis, Lagkadas A, A Lagkadas, O Polychronis, Polychronis O, S Natsis, Natsis S, Karakalpakis D, Defkalion Karakalpakis, D Karakalpakis, Giannakopoulos K, K. Giannakopoulos
European journal of gynaecological oncology · 2011 · vol. 32(6) , pp. 682–5 · PMID:22335037 · W2468573083
article OA: closed CC0 ⤵ 3 in-corpus citations
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This case report and literature review examine endometriosis-associated ovarian cancer, discussing its epidemiology, genetics, and other contributing factors to its pathogenesis.

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Abstract

Endometriosis is a frequent benign disease presenting in more than 10% of women in reproductive age. Although its course is usually benign, it has characteristics of malignant disease, such as progressive course, implantation at distant sites, creation of a microenvironment that renders its course independent and mobilization of the immune system in order to prevent its destruction. Endometriosis-associated ovarian cancer (EAOC) is encountered in 0.3-1.0% of cases of endometriosis. We present in the current article a case of EAOC, reviewing the literature for epidemiological data and data of genetics, and other possible associated factors that lead to the pathogenesis of the disease.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Ovarian Diseases Ovarian Neoplasms Adult Endometriosis Endometriosis Female Humans Loss of Heterozygosity Ovarian Diseases Ovarian Neoplasms Ovarian Neoplasms Ovarian Neoplasms

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License: CC0 · commercial use OK