Expression of estrogen receptor and progestergon receptor in endometrium of a rat model with endometriosis

To evaluate the expression of ER and PR mRNAs in rat endometrium tissue and to explore the pathogenesis of endometriosis. The expression of ER and PR mRNAs in ectopic endometrium was significantly lower than that in eutopic and normal endometrium ( P 0.01). No difference was observed between eutopic and normal endometium. Ratio of ER/PR mRNA in ectopic endometrium was higher than that in eutopic and in normal endometrium ( P 0.01). The result suggested that the increased ER played a vital role in the onset of endometriosis.