Endometriose endometriose en pijn

R. D. H. Boer, W. W. A. Zuurmond, Peter G.A. Hompes, Roberto S.G.M. Perez, S. A. Loer
In: Pijn Info · 2004 · pp. 1323–1328 · doi:10.1007/978-90-313-7316-1_227 · W40096224
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⚙ AI-generated summary by claude@2026-06, 2026-06-28 ⓘ

Endometriosis is a chronic condition where endometrial tissue grows outside the uterus, causing significant, difficult-to-treat pain in reproductive-aged women.

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⚙ AI-generated deep summary by claude@2026-07, 2026-07-09 · read from full text ⓘ

The paper/“chapter” reviews endometriosis as a chronic condition defined by endometrial tissue and stroma outside the uterine cavity and discusses its prevalence in reproductive-age women, emphasizing that it can cause severe, chronic pain that is often difficult to treat and requires a multidisciplinary approach. It positions pain-focused perspectives and references broader evidence around pelvic pain associated with endometriosis, including general management updates and pain mechanisms, with citations to topics such as NSAIDs, central sensitization, and neuropathic-pain–oriented medications (e.g., gabapentin or antidepressants) and other analgesic modalities. A major limitation is that the provided text does not include primary patient data or a detailed methods section, indicating it functions as a narrative overview rather than an original empirical study. This paper is centrally about endometriosis — it focuses on endometriosis and pain, framing the condition’s link to chronic pelvic pain and treatment approaches.

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Abstract

Endometriose is een chronische aandoening die wordt gekenmerkt door de aanwezigheid en proliferatie van endometrium en stroma buiten het cavum uteri. Het is een van de meest voorkomende aandoeningen bij vrouwen in de reproductieve leeftijd en kan zich uiten als een serieuze bron van chronische pijn, die veelal moeilijk behandelbaar is en om een multidisciplinaire aanpak vraagt.
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Samenvatting Endometriose is een chronische aandoening die wordt gekenmerkt door de aanwezigheid en proliferatie van endometrium en stroma buiten het cavum uteri. Het is een van de meest voorkomende aandoeningen bij vrouwen in de reproductieve leeftijd en kan zich uiten als een serieuze bron van chronische pijn, die veelal moeilijk behandelbaar is en om een multidisciplinaire aanpak vraagt. Afdeling Anesthesiologie, VU Medisch Centrum Amsterdam. Hoogleraar Anesthesiologie in het bijzonder de palliatieve zorg en pijnbestrijding, VU Medisch Centrum Amsterdam en Medisch Directeur Hospice Kuria. Hoofd afdeling Multidisciplinair Endometriose Centrum, VU Medisch Centrum Amsterdam. Coördinator onderzoek pijn en pijnbestrijding, afdeling Anesthesiologie, VU Medisch Centrum Amsterdam. Hoofd afdeling Anesthesiologie, VU Medisch Centrum Amsterdam. Referenties Augoulea A, Lambrinoudaki I, Chritodoulakos G. Thoracic endometriosis syndrome. Respiration 2008;75(1):113-9. Farquhar C. Endometriosis. British Medical Journal 2007;334(7587):249. The practice committee of the American society for reproductive medicine. Treatment of pelvic pain associated with endometriosis; Fertility and sterility 2006;86(5):S18-27. Evans S, Moalem-Taylor G, Tracey DJ. Pain and endometriosis. Pain 2007;132 Suppl 1:S22-25. Crosignani P, Olive D, Bergquist A, et al. Advances in the management of endometriosis: an update for clinicians. Hum Reprod Update 2006;12(2):179-89. Rodgers AK, Falcone T. Treatment strategies for endometriosis. Expert opin pharmacother 2008 Feb;9(2): 243-55. IASP (http://www.iasp-pain.org). Kyama CM, Mihalyi A, Simsa P, et al. Non-steroidal targets in the diagnosis and treatment of endometriosis. Curr Med Chem 2008;15(10):1006-17. Bajaj P, et al. Endometriosis is associated with central sensitization: a psychophysical controlled study. J Pain 2003 Sep;4(7):372-80. Greco CD. Management of adolescent chronic pelvic pain from endometriosis: a pain center perspective. J Pediatr adolesc gynecol 2003;16:S17-19. Bordman R, Jackson B. Below the belt – Approach to chronic pelvic pain. Can Fam Physician 2006;52:1556-62. European Society for Human Reproduction and Embryology (http://www.eshre.com). Fedele L, Bianchi S, Zanconato G, et al. Long-term follow-up after conservative surgery for rectovaginal endometriosis. Am J Obstet Gynecol 2004;190:1020-4. Selak V, Farquhar C, Prentice A, et al. Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst. Rev. 2007;(4): CD000068. Farmacotherapeutisch Kompas 2008 (www.fk.cvz.nl). Kauppila A, Ronnberg L. Naproxen sodium in dysmenorrhea secundary to endometriosis. Obstet Gynecol 1985;65(3):379-83. Allen C, Hopewell S, Prentice A. Non-steroidal anti-inflammatory drugs for pain in women with endometriosis. Cochrane Database Syst Rev 2005;(4):CD004753. Marjoribanks J, Proctor ML, Farquhar C. Nonsteroidal anti-inflammatory drugs for primary dysmenorrhoea. Cochrane database Syst Rev 2003;(4):CD001751. Biegstraaten M, Schaik IN van. Pregabaline bij de behandeling van neuropathische pijn. Ned Tijdschr Geneeskd 2007;151(28):1561-5. Sator-Katzenschlager SM, Scharbert G, Kress HG, et al. Chronic pelvic pain treated with gabapentin and amitriptylin: a randomized controlled pilot study. Wien Klin Wochenschr 2005;117(21-22):761-68. Ben-David B, Friedman M. Gabapentin therapy for vulvodynia. Anesth Analg 1999;89(6):1459-60. Walker EA, Roy-Byrne PP, Katon WJ, et al. An open trial of nortriptyline in women with chronic pelvic pain. Int J Psychiatry Med 1991;21(3):245-52. Liu X, Guo SW. A pilot study on the off-label use of valproic acid tot treat adenomyosis. Fertility and Sterility 2008;89 (1):246-50. Reiter RC. Evidence-based management of chronic pelvic pain. Clin Obstet Gynecol 1998;41(2):422-35. Sluka AK, Walsh D. Transcutaneous electrical nerve stimulation: basic science mechanisms and clinical effectiveness. J Pain 2003;4(3):109-21. Nnoaham KE, Kumbang J. Transcutaneous electrical nerve stimulation (TENS) for chronic pain. Cochrane database Syst Rev 2008;16(3):CD003222. Rosenberg EI, Genao I, Chen I, et al. Complementary and alternative medicine use by primary care patients with chronic pain. Pain Med 2008 Jun 18 [Epub ahead of print]. Molsberger AF, Mau J, Pawelec DB, et al. Does acupuncture improve the orthopedic management of chronic low back pain – a randomized, blinded, controlled trial with 3 months follow up. Pain 2002;99(3):579-87. Haake M, Mueller HH, Schade-Brittinger C. German Acupuncture Trials (GERAC) for chronic low back pain: randomized, multicenter, blinded, parallel-group trial with 3 groups. Arch Intern Med 2007;167(17):1892-8. Helms JM. Acupuncture for the management of primary dysmenorrhea. Obstet Gynecol 1987;69(1):51-6. Eccleston C, Yorke L, Morley S, et al. Psychological therapies for the management of chronic and recurrent pain in children and adolescents. Cochrane Database Syst Rev 2003;(1):CD003968. Hompes PGA, Mijatovic M. Endometriosis: the way forward. Gynecological Endocrinology 2007;23(1):5-12. Nederlandse Vereniging voor Obstetrie en Gynaecologie, www.nvog-documenten.nl/index.php?pagina=/richtlijn/item/pagina.php&richtlijn_id=668 Guidelines Endometriosis, http://www.eshre.com Kemper KJ, Sarah R, Silver-Highfield E, et al. On pins and needles? Pediatric pain patients’ experience with acupuncture. Pediatrics. 2000 Apr;105(4 Pt 2):941-7. Rights and permissions Copyright information © 2009 Bohn Stafleu van Loghum> About this chapter Cite this chapter Boer, R.D.H., Zuurmond, W.W.A., Hompes, P.G.A., Perez, R.S.G.M., Loer, S.A. (2009). Endometriose endometriose en pijn. In: Boekblok Pijn info. Pijn info. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-313-7316-1_227 Download citation DOI: https://doi.org/10.1007/978-90-313-7316-1_227 Published: Publisher Name: Bohn Stafleu van Loghum, Houten Online ISBN: 978-90-313-7316-1 eBook Packages: Dutch language eBook collection

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