Uterine stem cells—promise and possibilities

Lubna Pal, Pal L
Maturitas · 2015 · vol. 82(3) , pp. 282–283 · doi:10.1016/j.maturitas.2015.07.018 · PMID:26297687 · W1855332523
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This review explores the potential of uterine stem cells for regenerative medicine and therapeutic applications.

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Abstract

A fraction of cells residing in the uterine endometrium exhibit functional pluripotent potential, allowing them to be classified as adult stem cells. While the physiological relevance of this cell population is mostly conjectural at this juncture, uterine endometrial stem cells (UESC's) may underline pathogenesis of certain common gynecological disorders, such as endometriosis and adenomyosis. The ease of access and harvesting of UESC's and the diverse differentiation potential of this cell population has identified the uterine endometrium as a valuable source of autologous stem cells that can be harnessed through judicious application of principals of regenerative medicine. This mini review offers a glimpse into the journey, and an introduction to the spectrum of disorders that UESC's have the potential of impacting.

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Condition tags

endometriosis

MeSH descriptors

Adult Stem Cells Endometrium Regeneration Adult Stem Cells Animals Cell Differentiation Endometriosis Endometriosis Endometrium Female Humans

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References (23)

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License: CC0 · commercial use OK