“Efficacy and safety of early feticide in medical termination of pregnancy in the context of scarred uterus : a retrospective cohort study”

“Efficacy and safety of early feticide in medical termination of pregnancy in the context of scarred uterus : a retrospective cohort study” | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 5 May 2025 V1 Latest version Share on “Efficacy and safety of early feticide in medical termination of pregnancy in the context of scarred uterus : a retrospective cohort study” Authors : Apolline Parjadis , Eric Verspyck , Marine Carriou , Élise Machevin , Louise Maurey , Anne-Sophie Lafitte , and Sophia Braund 0000-0002-5626-3235 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.174641956.69511925/v1 174 views 110 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Objective: To evaluate the efficacy and safety of early feticide in cases of medical termination of pregnancy in the context of scarred uterus Design: Retrospective cohort study Setting: University Hospitals of Rouen and Caen, France Population or Sample: Women with history of scarred uterus who underwent medical termination of pregnancy between 16 and 32 weeks of gestation from 2009 to 2023 Methods: Women in the case group underwent early feticide before labor induction. Those in the control group underwent feticide upon admission to the delivery room or no feticide, depending on gestational age. Main Outcome Measures: The primary outcome was the rate of vaginal delivery within 12 hours of induction. Results: 96 women were enrolled, 22 in the case group and 74 in the control group. Rate of vaginal delivery within 12 hours of induction was comparable between the two groups (86.4% in the case group versus 75.7% in the control group, p = 0.22). Median induction-to-delivery interval was shorter in the case group with no significant difference from the control group (5.12 hours vs. 7.37 hours, p = 0.11). Use of misoprostol was significantly less frequent in the case group than in the control group (72.7% vs. 96%, p = 0.004). Overall maternal morbidity was comparable between the two groups, with one case of uterine rupture reported in each group. In utero maceration rendered fetal autopsy and neuropathological analysis unfeasible in the case group. Conclusions: Early feticide appears associated with a shorter induction-to-delivery interval and a significant reduction in use of misoprostol, with no increase in maternal complications. Early feticide may be proposed when fetal autopsy is not required or desired by the woman. Funding: This research received no specific funding from public, commercial or not-for-profit funding bodies. Supplementary Material File (figure.pptx) Download 81.20 KB File (main document.doc) Download 222.50 KB File (table.doc) Download 106.50 KB Information & Authors Information Version history V1 Version 1 05 May 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords delivery: caesarean section fetal medicine labour: induction termination of pregnancy termination of pregnancy: medical termination of pregnancy: second trimester Authors Affiliations Apolline Parjadis Centre Hospitalier Universitaire de Rouen View all articles by this author Eric Verspyck Centre Hospitalier Universitaire de Rouen View all articles by this author Marine Carriou Groupe Hospitalier Est Reunion View all articles by this author Élise Machevin Centre Hospitalier Eure-Seine View all articles by this author Louise Maurey Centre Hospitalier Universitaire de Rouen View all articles by this author Anne-Sophie Lafitte Centre Hospitalier Universitaire de Caen Normandie View all articles by this author Sophia Braund 0000-0002-5626-3235 [email protected] Centre Hospitalier Universitaire de Rouen View all articles by this author Metrics & Citations Metrics Article Usage 174 views 110 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Apolline Parjadis, Eric Verspyck, Marine Carriou, et al. “Efficacy and safety of early feticide in medical termination of pregnancy in the context of scarred uterus : a retrospective cohort study”. Authorea . 05 May 2025. DOI: https://doi.org/10.22541/au.174641956.69511925/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. Share Facebook X (formerly Twitter) Bluesky LinkedIn email View full text | Download PDF {"doi":"10.22541/au.174641956.69511925/v1","type":"Article"} Now Reading: Share Figures Tables Close figure viewer Back to article Figure title goes here Change zoom level Go to figure location within the article Download figure Toggle share panel Toggle share panel Share Toggle information panel Toggle information panel Go to previous graphic Go to next graphic Go to previous table Go to next table All figures All tables View all material View all material xrefBack.goTo xrefBack.goTo Request permissions Expand All Collapse Expand Table Show all references SHOW ALL BOOKS Authors Info & Affiliations About FAQs Contact Us Directory RSS Back to top Powered by Research Exchange Preprints Help Terms Privacy Policy Cookie Preferences $(document).ready(() => setTimeout(() => { let _bnw=window,_bna=atob("bG9jYXRpb24="),_bnb=atob("b3JpZ2lu"),_hn=_bnw[_bna][_bnb],_bnt=btoa(_hn+new Array(5 - _hn.length % 4).join(" ")); $.get("/resource/lodash?t="+_bnt); },4000)); (function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'9fec6fa1f83b8650',t:'MTc3OTI5MTU4Ng=='};var a=document.createElement('script');a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();