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This scoping review aimed to identify current areas of smartphone apps use for managing LBP. We also aimed to evaluate the current status of the effectiveness or scientific validity of such use and determine perspectives for their potential development. Methods We searched PubMed, PEDro and Embase for articles published in English up to May 3rd, 2021 that investigated smartphone use for LBP healthcare and their purpose. All types of study design were accepted. Studies concerning telemedicine or telerehabilitation but without use of a smartphone were not included. The same search strategy was performed by two researchers independently and a third researcher validated the synthesis of the included studies. Results We included 43 articles: randomised controlled trials (RCTs) (n=12), study protocols (n=6), reliability/validity studies (n=6), systematic reviews (n=7), cohort studies (n=4), qualitative studies (n=6), and case series (n=1). The purposes of the smartphone app were for 1) evaluation, 2) telerehabilitation, 3) self-management, and 4) data collection. Self-management was the most-studied use, showing promising results derived from moderate- to good-quality RCTs for patients with chronic LBP and patients after spinal surgery. Promising results exist regarding evaluation and data collection use and contradictory results regarding measurement use. Conclusions This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients. The identified purposes point to current scientific status and perspectives for further studies including RCTs and systematic reviews targeting specific usage. 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F1000Research 2024, 11 :1001 ( https://doi.org/10.12688/f1000research.123331.2 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. Close Copy Citation Details Export Export Citation Sciwheel EndNote Ref. Manager Bibtex ProCite Sente EXPORT Select a format first Track Share ▬ ✚ Systematic Review Revised Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] Lech Dobija https://orcid.org/0000-0002-9021-5704 1,2 , Jean-Baptiste Lechauve 2 , Didier Mbony-Irankunda 2 , Anne Plan-Paquet 2 , Arnaud Dupeyron 3,4 , Emmanuel Coudeyre https://orcid.org/0000-0001-5753-2890 1,2 Lech Dobija https://orcid.org/0000-0002-9021-5704 1,2 , Jean-Baptiste Lechauve 2 , [...] Didier Mbony-Irankunda 2 , Anne Plan-Paquet 2 , Arnaud Dupeyron 3,4 , Emmanuel Coudeyre https://orcid.org/0000-0001-5753-2890 1,2 PUBLISHED 07 May 2024 Author details Author details 1 UNH, INRAE, Université Clermont-Auvergne, Clermont-Ferrand, Puy de Dôme, 63000, France 2 Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, Puy de Dôme, 63118, France 3 Université Montpellier, Nimes, 30900, France 4 Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Nimes, Nimes, 30900, France Lech Dobija Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Jean-Baptiste Lechauve Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing Didier Mbony-Irankunda Roles: Formal Analysis, Methodology, Writing – Review & Editing Anne Plan-Paquet Roles: Conceptualization, Methodology, Supervision, Writing – Review & Editing Arnaud Dupeyron Roles: Conceptualization, Methodology, Supervision, Writing – Review & Editing Emmanuel Coudeyre Roles: Conceptualization, Formal Analysis, Funding Acquisition, Methodology, Supervision, Validation, Writing – Review & Editing OPEN PEER REVIEW DETAILS REVIEWER STATUS This article is included in the Digital Healthcare collection. Abstract Background Smartphone use has grown in providing healthcare for patients with low back pain (LBP), but the literature lacks an analysis of the use of smartphone apps. This scoping review aimed to identify current areas of smartphone apps use for managing LBP. We also aimed to evaluate the current status of the effectiveness or scientific validity of such use and determine perspectives for their potential development. Methods We searched PubMed, PEDro and Embase for articles published in English up to May 3rd, 2021 that investigated smartphone use for LBP healthcare and their purpose. All types of study design were accepted. Studies concerning telemedicine or telerehabilitation but without use of a smartphone were not included. The same search strategy was performed by two researchers independently and a third researcher validated the synthesis of the included studies. Results We included 43 articles: randomised controlled trials (RCTs) (n=12), study protocols (n=6), reliability/validity studies (n=6), systematic reviews (n=7), cohort studies (n=4), qualitative studies (n=6), and case series (n=1). The purposes of the smartphone app were for 1) evaluation, 2) telerehabilitation, 3) self-management, and 4) data collection. Self-management was the most-studied use, showing promising results derived from moderate- to good-quality RCTs for patients with chronic LBP and patients after spinal surgery. Promising results exist regarding evaluation and data collection use and contradictory results regarding measurement use. Conclusions This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients. The identified purposes point to current scientific status and perspectives for further studies including RCTs and systematic reviews targeting specific usage. READ ALL READ LESS Keywords Smartphone apps, low back pain, mHealth, self-management, telerehabilitation Corresponding Author(s) Lech Dobija ( [email protected] ) Close Corresponding author: Lech Dobija Competing interests: No competing interests were disclosed. Grant information: This work was supported by Centre Hospitalier Universitaire de Clermont-Ferrand and Université Clermont Auvergne. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Copyright: © 2024 Dobija L et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. How to cite: Dobija L, Lechauve JB, Mbony-Irankunda D et al. Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.12688/f1000research.123331.2 ) First published: 06 Sep 2022, 11 :1001 ( https://doi.org/10.12688/f1000research.123331.1 ) Latest published: 07 May 2024, 11 :1001 ( https://doi.org/10.12688/f1000research.123331.2 ) Revised Amendments from Version 1 The article has been modified according to reviewers' comments. This includes some clarifications and sentence reformulations. We hope that the changes made improve the readability of the article. The article has been modified according to reviewers' comments. This includes some clarifications and sentence reformulations. We hope that the changes made improve the readability of the article. See the authors' detailed response to the review by Marijn Ulrich See the authors' detailed response to the review by Alexandra Roren READ REVIEWER RESPONSES Introduction Technological development has accelerated notably in the field of telecommunication in the last few decades. Since the introduction of the first mobile phones, the number of users has continued to grow and is now estimated at 6.8 billion worldwide. 1 Mobile phones have gained new capabilities such as better Internet connection, allowing them to substitute for personal computers to a large extent. This new generation of mobile phones, called smartphones, has changed a lot of human activity. The number of smartphone users worldwide has surpassed three billion and is forecast to further grow. 2 Extensive software of smartphones has permitted the development of new applications, allowing video communication, social media consulting, gaming, and navigation. The potentially inexhaustible use of the smartphones cannot be ignored in any human activity including healthcare. The dynamic technological development has been accompanied by a less spectacular increase in life expectancy. However, simultaneously, the rate of years living with disability (YLD) has stagnated or even increased for some diseases. The last estimations of the YLD positioned low back pain (LBP) as a leading cause of handicap worldwide. 3 Besides the obvious healthcare problem, the economic impact of LBP is serious, with the total mean cost per patient over six months estimated at EUR 715.6 in France. 4 One of the aspects of this problem is that LBP could be chronic or recurrent in nature and affects middle-aged, professionally active adults. Chronic LBP concerns less than 10% of cases but 85% of the costs. 5 A further problem is that in most cases, physicians are unable to reliably identify the cause of the LBP symptoms, so they classify them as non-specific. When nonspecific LBP persists and becomes chronic, it becomes increasingly complex and challenging to manage due to its multifactorial nature. 6 Failure of the purely biomedical approaches targeting only pathoanatomical nociceptive aspects has led to the development of the more exhaustive bio-psycho-social model. This multidimensional approach encompasses psychological, biological, social, and environmental aspects. 7 Current guidelines for management of chronic LBP include psychosocial interventions along with exercise therapy, medications, multidisciplinary rehabilitation and spinal manipulation. 8 Completing the context of LBP, some authors highlight the problem of overtreating. Expanding testing and treatment by using therapies and diagnostic tools with weak scientific validity can drive increasing complication rates, marketing abuse and patients’ confusion. 9 The widespread occurrence of LBP self-management strategies seems appropriate to target economic and healthcare accessibility problems. 10 Smartphone applications (apps) for this purpose appear to be promising tools, giving a wide range of possibilities for use, replacing education booklets, proposing and supervising exercise therapy (telerehabilitation), and stimulating adherence for self-management programs. Using smartphone apps are the most accessible way to provide rehabilitation services and to collect outcomes remotely as smartphones are personal and always available to patients. 11 , 12 Such a new model makes health services more accessible and enhances patient participation and their engagement in self-management. 11 Compared to face-to-face treatment smartphone apps could potentially be more cost-effective and could help to overcome the problem of healthcare accessibility. This idea has been developed in other healthcare intents such as diabetes, 13 chronic obstructive pulmonary disease, 14 and osteoarthritis. 15 However, smartphones equipped with multiple sensors, cameras, gyroscopes, accelerometers, and magnetometers could also be used as tools for range-of-motion (ROM) measurement 16 or could be simply used with the phone camera for clinical evaluation at a distance. 17 Another feature is that smartphone apps could be used for surveying large population samples, allowing to create a database for more sophisticated analyses including case-based reasoning systems. 18 Moreover, the need for healthcare management at a distance (telemedicine) has become crucial in the recent situation requiring confinement due to the coronavirus disease 2019 (COVID-19) pandemic. Without the possibility to access conventional healthcare face-to-face with providers, numerous clinicians were challenged to provide telemedicine in order to substitute conventional healthcare in non-essential services. 19 , 20 Smartphone applications have become highly pertinent tools for this purpose. Indeed, the use of smartphone apps has increased for LBP patients. However, there is a lack of synthesis of the scientific literature in the areas of smartphone app use. Moreover, it is not clear in what purpose using smartphone apps are pertinent and if such use is supported by the scientific studies. Giving a large range of area of interest and the fact that it is a new dynamically developing subject we believe that performing a scoping review will clarify these questions. The objective of this scoping review is to identify current areas of smartphone app use for managing LBP. It also aimed to evaluate the current status of the effectiveness or scientific validity of smartphone app use and to determine perspectives for their potential development. Methods Protocol and registration Review protocol presenting search strategy was established without a registration number. Information sources and search strategy The Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist was used to guide the present study. 21 , 63 Two researchers (LD and JBL) independently searched for articles in PubMed (RRID:SCR_004846), PEDro and EMBASE (RRID:SCR_001650) by using MeSH keywords. The search strategy phrase for PubMed database was (“smartphone application” OR “smartphone app” OR “smartphone” OR “telerehabilitation” OR “telemedicine” OR “mhealth” OR “ehealth”) AND (“low back pain” OR “back pain”). Corresponding research was realized in PEDro and EMBASE by using the same keywords. Only English language and time frame filters were used for our research. The articles were screened and assessed for eligibility regarding the objective of the study. Articles published between January 1st 2005 and May 3rd 2021 were considered. This time frame includes the emergence of the new generation of mobile phones. Eligibility criteria Only studies of smartphone use in LBP adult patient healthcare were included. We excluded studies concerning telemedicine or telerehabilitation but without use of a smartphone. Similarly, we excluded studies in which the smartphone use involved healthy individuals for preventing LBP or promoting physical activity or a healthy lifestyle in healthy individuals. To broaden our review, all qualitative and quantitative studies were accepted, including randomised controlled trials (RCTs) and non-randomized studies, cohort studies, case-control studies, systematic reviews, reliability and validity studies, and study protocols. In cases where both the protocol and the completed study article were published, we included both to ensure comprehensive content analysis of the literature on the subject. Only studies accepted for publication, written in English were considered. Selection of sources of evidence Study inclusion was discussed to reach agreement or in cases where a consensus could not be reached, we consulted with a third researcher (EC). Then studies were classified according to the purpose of the smartphone app. The type of study design was also used to classify studies in terms of its objective: effectiveness of the smartphone use, reliability of the smartphone measures, or other type of evaluation and data collection. Data charting process Search strategy was prepared and validated with the participation of all authors of the present review. The same search strategy was realized by two researchers (LD and JBL) independently. A third researcher (EC) participated in the synthesis data charting. Then, additional articles were identified throughout citation matching. Data items We extracted data concerning smartphone app utilisation. We focused on the purpose of smartphone app utilisation, study design, date of publication, number of participants who completed the study, main outcomes, results and authors conclusions. Critical appraisal of individual sources of evidence The quality of selected RCTs was estimated by using the PEDro scale. 22 Synthesis of results We categorized included studies by the purpose of smartphone app utilisation. The synthesis of the included studies was also done by study design, both were presented in a narrative format and in a synthesis table. Results We identified 43 articles based on our search strategy ( Figure 1 ). The included studies were RCTs (n=12), study protocols (n=6), reliability/validity studies (n=6), systematic reviews (n=7), cohort studies (n=4), qualitative studies (n=6), and case series (n=1) ( Table 1 ). Figure 1. Flow diagram of studies selection. Table 1. List of articles included in the scoping review. Author, publication date (reference number) Study design Objective Purpose of the smartphone use Nordstoga, 2020 56 Qualitative feasibility and quantitative pilot study To assess the usability and acceptability of the selfBACK smartphone app. SM, DC Grolier, 2020 55 Mixed quantitative and qualitative approaches To refine the design of a smartphone application for people with chronic non-specific LBP. SM Almhdawi, 2020 58 Pilot RCT To evaluate the effectiveness of a newly developed evidence-based LBP management using smartphone app on pain and disability. SM Pourahmadi, 2020 30 Systematic review To evaluate available evidence in the literature to assess the psychometric properties of the iHandy Level app in measuring lumbar spine ROM and lordosis. E Coe-O'Brien, 2020 33 Systematic scoping review To assess the quality of the free Smartphone Apps for LBP; outcome measures used; the outcome measures against the International Classification of Functioning, Disability and Health core set classifications for LBP. SM, E Sandal, 2019 50 Protocol of RCT To evaluate the effectiveness of using the selfBACK app to support self-management in addition to usual care versus usual care only in people with non-specific LBP on pain-related disability. SM, DC Pourahmadi, 2019 27 Reliability study To evaluate the reliability and validity of an application (iHandy® Level) for measuring active lumbar flexion-extension ROM in chronic non-specific LBP patients. E Pourahmadi, 2019 16 Systematic review To evaluate available evidence in the literature to assess the psychometric properties of the iHandy Level app in measuring lumbar spine ROM and lordosis. E Riis, 2018 53 Qualitative study To identify preferences for the content, design, and functionality of a Web app with evidence-based information and advice for people with LBP. SM Machado, 2016 10 Systematic review of the LBP apps To screen app stores for the self-management of LBP apps and evaluate their content quality and whether they recommend evidence-based interventions. SM Dario, 2017 40 Systematic review with meta-analysis To evaluate whether interventions delivered by telehealth improve pain, disability, function, and quality of life in non-specific LBP. TR Farasyn, 2013 34 Reliability, validity study with RCT design To explore the reliability, responsiveness and concurrent validity of the BADIX score using an app. E Stienen, 2019 31 Validity study To compare 6-minute walking distance measurements obtained with a newly developed smartphone application and those obtained with the gold-standard distance wheel. E Mork, 2018 18 Study protocol To implement a Decision Support System for self-management of non-specific LBP, utilizing smartphone app to develop personalized self-management plans and evaluate its effect. SM Verbrugghe, 2017 39 Qualitative study To investigate inventory training preferences and motives, evaluate whether these change during rehabilitation, and evaluate familiarity with using technologies, in persons with non-specific LBP. SM, TR Blödt, 2014 51 Study protocol To evaluate whether an additional app-delivered relaxation is more effective in the reduction of chronic LBP than usual care alone. SM Mbada, 2019 32 Randomized trial To compare the effects of Telerehabilitation-Based McKenzie Therapy and Clinic-Based McKenzie Therapy among patients with LBP. E, TR Hou, 2019 38 RCT To evaluate the effectiveness of mobile phone-based rehabilitation systems on pain and disability in patients who underwent lumbar spinal surgery. TR, SM Peterson, 2018 37 Case series To describe the implementation of Telerehabilitation booster sessions and remote patient monitoring in three patients with chronic LBP. TR, SM Peterson, 2019 17 Validity study To evaluate the agreement between telerehabilitation and face-to-face assessments of patients with acute and subacute LBP using a modified treatment-based classification system, and patient satisfaction. E, TR Amorim, 2016 45 Protocol of RCT To investigate the effectiveness of a mobile health supported physical activity intervention in care-seeking, pain and disability in people with chronic LBP after discharge from treatment. TR, SM Amorim, 2019 36 RCT pilot To evaluate the feasibility and preliminary effectiveness of a patient-centred physical activity intervention, supported by health coaching and mobile health, to reduce care-seeking, pain and disability in patients with chronic LBP. TR, SM Chhabra, 2018 11 RCT To evaluate the effect of using a smartphone app on pain and function in patients suffering from chronic LBP. SM, DC Jamison, 2019 25 RCT To examine the benefit of a high-frequency transcutaneous electrical nerve stimulation device for patients with chronic LBP. E, DC Lin, 2019 24 Pilot study, clinical trail To evaluate the feasibility and usability of an ecological momentary pain assessment with a smartphone application. E, DC Lee, 2016 28 RCT To evaluate the effects of the Graston technique and general exercise on pain and range of motion in patients with chronic LBP. E Ross, 2020 26 Retrospective cohort study To identify factors that predicted the benefits and future use of a smartphone pain app among patients with chronic pain. SM, E, DC Hasenöhrl, 2020 35 Qualitative feasibility and quantitative pilot study To evaluate the feasibility and acceptance of orthopaedists prescribing individualized therapeutic exercises via a smartphone app to patients suffering from non-specific LBP. TR, SM Corrêa, 2020 23 Reliability, validity study To test the inter- and intra-rater reliabilities and concurrent validity of smartphone app for quantification of pain drawings in patients with LBP. DC, E Yeh, 2020 59 Study protocol of RCT To test auricular point acupressure as a non-invasive, non-pharmacological self-management strategy to manage chronic LBP. DC O' Halloran, 2019 52 Study protocol of RCT To describe the design of a cluster RCT evaluating the effect of Motivational Interviewing combined with usual physiotherapy care and a specifically designed app to increase physical activity in people with LBP. SM Carpenter, 2019 60 Cohort study To evaluate reciprocal associations between opioid use and physical pain using ecological momentary assessment via a smartphone app. DC de Brito Macedo, 2020 29 Reliability, validity study To evaluate the concurrent validity and the intra-rater reliability of thoracolumbar range of motion measurement using a mobile application and a digital inclinometer in individuals with and without back pain. E Yang, 2019 57 RCT - pilot study To evaluate the additional effect of self-management on physiotherapy via the use of smartphone app on management of chronic LBP. SM Du, 2019 46 Systematic review & meta-analysis To evaluate the effectiveness on pain intensity and disability of eHealth based self-management programs on chronic LBP. SM Suman, 2019 48 Cluster RCT To evaluate the effectiveness and cost-utility of a multifaceted eHealth strategy compared to usual care in improving patients' back pain beliefs, and in decreasing disability and absenteeism. SM Selter, 2018 44 Clinical trial - pilot study To examine patient engagement, patient-perceived utility with the smartphone app-based self-management program and assess the validity of the Your Activities of Daily Living module for quantifying functional status among patients with chronic LBP. SM, TR Clement, 2018 42 Retrospective cohort study To elucidate the effect on user retention and clinical outcomes of an updated version of the Kaia app. DC, SM, TR Toelle, 2019 41 RCT To evaluate the clinical effects of a multidisciplinary mHealth back pain App ( Kaia App) in an RCT. SM, TR Huber, 2017 43 Retrospective cohort study To report on the retrospective short-term results of a digital multidisciplinary pain app ( Kaia App) for the treatment of LBP. DC, SM, TR Ganguli, 2017 54 Qualitative study To facilitate local video creation to deliver targeted information to patients. SM, DC Nicholl, 2017 47 Systematic review To review the use of interactive digital interventions to support self-management of LBP. SM Irvine, 2015 49 RCT To evaluate the effectiveness of a mobile-Web intervention called FitBack on physical, behavioral, and worksite outcomes, to help users implement self-tailored strategies to manage and prevent LBP. SM We identified the following purposes of the smartphone apps: 1) evaluation, 2) telerehabilitation, 3) self-management or 4) data collection. We distinguished telerehabilitation and self-management because of a difference when the remote interaction between healthcare professional and patients occurred for LBP management (telerehabilitation). By contrast, some smartphone apps provide instructions for LBP management without giving feedback from a healthcare professional (self-management). Furthermore, the data collection use in most smartphone apps was coupled with other employment-like evaluations or self-management, but in some studies, the smartphone app was mainly dedicated to collecting information for further analysis. Use of smartphone apps for evaluation A total of 14 studies used smartphone apps as an evaluation tool including pain evaluation, 23 – 26 ROM measurement, 16 , 27 – 30 6-min walk test 31 and clinical or functional evaluation. 17 , 32 – 34 Considering pain evaluation, PainMAP showed excellent intra- and inter-rater reliability and good validity for quantifying the number of pain sites and pain area. 23 This application allows patients to mark their pain on digital body charts and automatically quantifies such self-assessment. Furthermore, another smartphone app could effectively evaluate pain changes after transcutaneous electrical nerve stimulation. 25 However, Ross et al. , reported that patients with chronic pain who appeared to manage their pain better were less likely to report benefits of a smartphone pain app designed for daily pain management and evaluation. 26 Smartphone apps were used to measure lumbar spine ROM and lordosis but showed insufficient reliability and validity as compared with a gravity-based inclinometer. 27 By contrast, de Brito Macedo et al. , reported good concurrent validity and intra-rater reliability of smartphone thoracolumbar ROM measurements versus a digital inclinometer. 29 Lumbar ROM measurement with a smartphone detected a significant difference due to manual therapy and exercise intervention in another study. 28 Similar findings were further summarized in systematic review showing contradictory results of psychometric properties of the lumbar spine ROM and lordosis measurements with a smartphone app. 30 Other examples of smartphone use included clinical and functional evaluation. Peterson et al. , suggested that a modified treatment-based classification system for subgrouping patients with LBP could direct treatment in telerehabilitation settings (smartphone app) because the overall rate of percentage agreement with face-to-face assessments was between 48.9% and 59.6%. 17 The McKenzie classification and therapy applied with a smartphone app showed comparable clinical outcomes with the traditional clinic-based McKenzie therapy. 32 The 6-min walk test performed with a smartphone app and using a GPS system could be reliable but needed to be performed avoiding indoors and city environments with high buildings and rectangular walking curses. 31 However, in a scoping review of outcomes with smartphone apps used for LBP management, authors showed the problem of low quality of the outcome measures to monitor the treatment effect. Indeed, only a few smartphone apps offered to monitor their effectiveness in the management of LBP. 33 Other examples of smartphone use for clinical evaluation is the use of the Backache Disability Index. Such evaluation includes rating five trunk movements in the erect position and scoring morning back stiffness. Performed remotely with a smartphone app, the index showed good reliability and validity. 34 Use of smartphone apps for telerehabilitation A total of 12 studies presented smartphone apps as a tool for providing rehabilitation interventions at a distance (telerehabilitation). 17 , 32 , 35 – 44 Despite different designs and aims, most of the studies evaluated the effectiveness of the smartphone app use in telerehabilitation on pain and disability. Dario et al. , performed a systematic review with meta-analysis to evaluate the effectiveness of the intervention based on any form of telerehabilitation, phone calls, emailing, and web-based chats but also smartphone apps. On the basis of data from 11 included studies, the authors concluded moderate evidence that current telerehabilitation interventions are not more effective than minimal interventions on pain and disability outcomes. Their study also revealed that the effectiveness of such interventions remains understudied. 40 Indeed, only three RCTs evaluated the effectiveness of the smartphone apps use to provide telerehabilitation in LBP patients. Hou et al. , evaluated a system of telerehabilitation based on a smartphone app interface for patients after lumbar surgery for LBP and a web-based interface for physicians providing and surveying rehabilitation and communicating with the patient. The authors demonstrated that the intervention was more effective than usual care regarding disability and pain status (Ostwestry Disability Index, pain visual analogue scale) at 24-month follow-up. 38 Mbada et al. , in their RCT, compared telerehabilitation-based McKenzie therapy versus the same treatment but provided in the traditional face-to-face setting. The smartphone app interface was used to introduce the treatment and was supported by phone calls and text messages in the experimental group. In this study, clinical improvement was noted at 4- and 8-week follow-ups, but no difference was found between the two groups in pain intensity, back muscle endurance and activity limitation. Thus, the authors concluded that smartphone app-based McKenzie telerehabilitation can be successfully used especially to bridge the gap in the non-availability of clinic-based therapy. 32 Toelle et al. , investigated the effect of a multidisciplinary smartphone app ( Kaia App ) on pain intensity at 12-week follow-ups in an RCT design. The experimental group received multidisciplinary self-management treatment based on current guidelines and supported by a chat with a healthcare professional via the app. The experimental group showed significantly lower pain intensity than the group receiving physiotherapy with on-line education. 41 The Kaia App was evaluated previously in a retrospective cohort study and showed good effect on pain intensity reduction, 43 and the analysis of the updated version of Kaia App revealed improvement in treatment adherence. 42 One more pilot RCT confirmed the feasibility and preliminary effectiveness of a physical activity intervention supported by a smartphone app on pain and disability. At the same time, patient acceptance and reduced care-seeking were observed. 36 The protocol of this study is detailed in a separate article. 45 Other studies focused on qualitative analysis of the patient’s preferences and compliance in the smartphone app use 35 , 39 and case series analysis of feasibility, effectiveness on pain and exercices adherence, and patient satisfaction with the telerehabilitation booster session. 37 Selter et al. , in their pilot study, assessed the validity of an image-based quantification of pain-related disability as well as patient compliance and patient-perceived utility of the smartphone app ( Limbr ). 44 The results showed good compliance and patient-perceived utility. In addition, the authors noted good validity of an image-based quantification of pain-related disability. 44 Use of smartphone apps for self-management The most-studied use of the smartphone app in LBP patients was for self-management. We identified 29 articles focused on self-management of LBP via a smartphone app: four systematic reviews, 10 , 33 , 46 , 47 five RCTs, 11 , 38 , 41 , 48 , 49 five study protocols, 18 , 45 , 50 – 52 six qualitative studies, 35 , 39 , 53 – 56 three retrospective cohort studies, 26 , 42 , 43 five pilot RCTs, 36 , 44 , 57 , 58 and one case series. 37 Many of the studies coupled the self-management and telerehabilitation in the same app or in the same study intervention. These studies were presented in the previous section. 32 , 35 – 45 In a scoping review of the outcome used in the smartphone apps for self-management of LBP, Coe-O’Brien et al. , found 74 apps; only four used the outcome measure that could be linked to the International Classification of Functioning, Disability and Health System (ICF) core set for LBP. Furthermore, they concluded that most of the apps were of low quality, indicating the lack of outcome evaluation in the apps. 33 Machado et al. , performed a systematic review of smartphone apps for self-management of LBP. Similarly, they analysed 61 apps and found overall low quality of the apps, pointing to the lack of studies evaluating their effectiveness, presentation of the questionable information, and unattractive layouts. They also recommend that app developers collaborate with healthcare professionals and researchers to ensure the benefit for LBP patients. 10 A recent systematic review with meta-analysis analysed eHealth based self-management for chronic LBP. The term eHealth encompassed the interventions based on smartphone apps (m-Health) or on traditional Internet (web-Health) use, so studies included in this meta-analysis were not all based on smartphone apps. Nevertheless, the authors concluded low to moderate evidence of a positive impact on pain and disability of this type of self-management. 46 Previously Nicholl et al. , performed a systematic review of digital support interventions for the self-management of LBP. They revealed heterogeneity and low quality of the studies, which could not support the utility of digital based interventions for LBP. 47 A summary of the RCTs focused on effectiveness of smartphone apps targeting self-management for LBP is presented in Table 2 as is the quality evaluation using the PEDRO score. Chhabra et al. , evaluated the effect of the self-management app Snapcare. A control group of LBP patients received a written prescription of medication and home exercises and were compared to a self-management group focusing on physical activity improvement based on Snapcare. The results at 12 weeks showed a similar improvement in pain in both groups and greater improvement in function in the Snapcare than control group. The authors concluded that such results support the utility of Snapcare for LBP patients. 11 Suman et al. , performed a cluster RCT evaluating the effectiveness and cost-utility of a multifaceted eHealth intervention based on websites and social media platforms but also including a mobile version, adaptable to a smartphone. The intervention was inspired by the Australian mass media campaign promoting physical activity, positive back beliefs and coping with LBP. The control group received a digital patient information letter. The presented eHealth strategy was not effective in improving patients’ back pain beliefs or decreasing disability or absenteeism, but the study provided a favourable cost-utility analysis. 48 Irvine et al. , showed that their mobile app FitBack was effective in improving physical, behavioural and worksite outcomes. FitBack was based on a self-tailored cognitive-behavioural approach and used the American Pain Society recommendations. 49 Almhdawi et al. , also reported that use of their app called Relieve my back is efficient in pain and disability self-management. 58 Table 2. Summary of randomized controlled trials evaluating smartphone app-based self-management interventions for patients with low back pain (LBP). Author, date (reference number) Title N of subjects who completed the study Objective Main outcomes and follow-up time Results Authors’ conclusion PEDro score Almhdawi, 2020 58 Effectiveness of an innovative smartphone application for office workers with chronic non-specific LBP: a pilot RCT n=40, EG, CG. To evaluate the effectiveness of a newly developed evidence-based LBP management smartphone application. Pain VAS, ODI, SF-12 at 6 weeks follow-up. Significant pain improvement in EG group vs. CG (-3.45 (2.21) vs. -0.11 (1.66), p<0.001), in ODI score (-11.05 (10.40) vs. -0.58 (9.0), p=0.002), Significant increase in physical component of SF-12 (12.85 (17.20) vs. -4.63 (12.04), p=0.001). ‘ Relieve my back ’ app reduce pain and disability and improve the quality of life of office workers with non-specific LBP. 9/10 Mbada, 2019 32 Comparative effectiveness of clinic-based and Telerehabilitation Application of Mckenzie Therapy in chronic LBP. CBMT group (n=26), TBMT group (n=21). Compare the effects of TBMT and CBMT among patients with LBP. PI, BEME, AL, PR, and GHS evaluated at 4 and 8 weeks. Both groups improved significantly on PI, BEME, AL, PR and GHS (all p=0.001); no significant differences in treatment effects between TBMT and CBMT. Smartphone-app based McKenzie therapy has comparable clinical effect with the traditional CBMT. 7/10 Hou, 2019 38 The effectiveness and safety of utilizing mobile phone-based programs for rehabilitation after lumbar spinal surgery: Multicentre, prospective RCT. Mobile phone-based EH group (n=84), UC treatment group (n=84). The effectiveness of mobile phone-based rehabilitation systems in patients who underwent lumbar spinal surgery. ODI, pain VAS, at baseline, 3, 6, 12, and 24 months postoperatively. EH group present better ODI than UC group ODI at 24 months postoperatively, no significant difference in primary outcomes at other time points. Mobile phone-based telerehabilitation program is effective in postoperative self-managed for patients after LBP surgery. This was more evident in participants with higher compliance. 7/10 Amorim, 2019 36 Integrating Mobile-health, health coaching, and physical activity to reduce the burden of chronic LBP trial (IMPACT): a pilot RCT. Intervention group (n=31), control group (n=24) Investigate the feasibility and preliminary effectiveness of a patient-centred physical activity intervention, supported by health coaching and mobile health, to reduce care-seeking, pain and disability in patients with chronic LBP. Care-seeking, pain levels and activity limitation evaluated at baseline, 6-month and weekly for 6 months. Care seeking reduction in intervention group (38%). No between-group differences for pain levels or activity limitation. Mobile-health coaching physical activity approach was feasible and well accepted by participants and may reduce care-seeking in patients with LBP. Further study with better statistical power is needed. 8/10 Chhabra, 2018 11 Smartphone app in self-management of chronic LBP: an RCT. App group (n=45), control group (n=48). The purpose of this study was to examine the effect of using a smartphone app (called Snapcare ) on pain and function in patients with chronic LBP. NPRS and MODI, evaluated at baseline and after 12 weeks of treatment. Both groups improved in NPRS and MODI (p<0.05). The app group showed a significantly greater improvement in MODI (p<0.001). Snapcare app facilitated an increase in physical activity and improved pain and disability in patients with chronic LBP. 7/10 Yang, 2019 57 Smartphone-based remote self-management of chronic LBP: a preliminary study. Self-management + physiotherapy group (n=5), control group physiotherapy only (n=3). To assess the additional effect of self-management on physiotherapy by the use of apps on management of chronic LBP. Pain VAS, PSEQ, RMDQ, and SF36. Baseline, week 2, and week 4 posttreatment. Experimental group was better in PSEQ (p=0.035), RMDQ (p=0.035), SF36-Bodily Pain (p=0.008), and SF36-Mental Health (p=0.013). Smartphone app-based self-management program gives additional benefits to physiotherapy for patients with chronic LBP. 5/10 Suman, 2019 48 Effectiveness and cost-utility of a multifaceted eHealth strategy to improve back pain beliefs of patients with non-specific LBP: a cluster randomised trial. Intervention group (n=200), control group (n=347). To assess the effectiveness and cost-utility of a multifaceted eHealth strategy (including mobile version) compared to usual care in improving patients' back pain beliefs, and in decreasing disability and absenteeism. BBQ, RDQ-24, PRODISQ, and TIC-P at baseline, 3, 6 and 12 months. No differences between groups in back pain beliefs, disability, or absenteeism. Mean intervention costs were in favour of the intervention group (EUR 70, and the societal cost difference EUR 535), but no significant cost savings were found. The ICER showed that the intervention dominated usual care and the probability of cost-effectiveness was 0.85 on a willingness-to-pay of EUR 10.000/QALY. Promising cost-utility results based on QALYs are in favour of eHealth strategy. However, it was not accompanied by improving patients' back pain beliefs or decreasing disability and absenteeism. 8/10 Toelle, 2019 41 App-based multidisciplinary back pain treatment vs. combined physiotherapy plus online education: an RCT. Kaia App group (n=42), control group (n=44). To investigate the clinical effects of a multidisciplinary mHealth back pain app ( Kaia App ) in an RCT. NRS for pain intensity, at 12-week. Kaia App group reported significantly better pain improvement than the control group (mean 2.70 [1.51] vs. 3.40 [1.63]). App-based multidisciplinary back pain treatment is effective for LBP patients and is better than physiotherapy combined with online education. 5/10 We also found several articles presenting study protocols for smartphone apps used by LBP patients. Sandal et al. , presented the protocol of an RCT comparing the effect of usual care supported by the selfBACK app versus usual care only. Tailored self-management plans were provided by the selfBACK app consisting of advice on physical activity, physical exercises, and educational content. Self-management plans were prepared by using case-based reasoning methodology, a branch of artificial intelligence. 50 Mork et al. , presented complementary information regarding the implementation of the methodology used in the selfBACK protocol. 18 One RCT protocol aimed to evaluate the effectiveness of Relaxback , focusing on relaxation for LBP patients in reducing pain. Autogenic training, mindfulness meditation and guided imagery is used in the app and will be compared to usual care. 51 Another RCT protocol is for MIMate , designed to support motivational interviewing performed by a physical therapist and targeting behavioural changes regarding physical activity. MIMate is used between face-to-face physical therapy sessions and is compared to usual physical therapy sessions. 52 Two qualitative studies coupled telerehabilitation and self-management interventions and were mentioned in the previous section. 32 , 36 Nevertheless, four other qualitative studies investigated the preference in content of an app improving self-management 53 , 55 or the feasibility/utility of an app providing educational videos focused on self-management, postoperative protocols, or tailored self-management plans. 54 , 56 Three retrospective cohort studies using smartphone apps for self-management of LBP were coupled with telerehabilitation, evaluation or data collection and were mentioned in the previous sections. 26 , 42 , 43 Similarly, in two pilot studies, self-management was coupled with telerehabilitation; these articles were presented in the previous section. 36 , 44 However, another pilot RCT, used a smartphone app to enhance self-management between physical therapy sessions and compared it to physical therapy only. The Pain Care app provided self-management based on home exercises. The authors concluded that a more powerful study needed to be conducted considering their promising results. 57 Use of smartphone apps for data collection Some studies used smartphone apps for LBP patients to collect medical information. One study protocol presented a smartphone app to collect timely data in ecological situations, including pain intensity, physical function, analgesic use and adherence to auricular point acupressure treatment. 59 Similarly, in a study that aimed to evaluate relations between opioid use and pain intensity, a smartphone app was used exclusively to collect information about pain intensity multiple times daily. 60 However, in most studies, data were collected together with other uses of the smartphone app previously presented: self-management, telerehabilitation, evaluation. 23 – 26 , 42 , 43 , 50 , 54 Discussion The aim of this scoping review was to identify the current fields of employment of smartphone apps for LBP patients. Although the use of smartphone apps for LBP patients is relatively recent, the scope of our review appears to be large, with 43 articles meeting our inclusion criteria. Emerging uses of the smartphone apps are self-management, telerehabilitation, evaluation and data collection. The present review did not aim to firmly classify use of the smartphone apps, as their multiple uses can be controversial. Rather we aimed at investigating what could be the utility of the apps for LBP patients, the current scientific knowledge and perspectives that are worthy of study and development. We observed a notable interest in scientific literature regarding the utilization of smartphone apps for patients with LBP. Self-management is a field of smartphone app use that has gained the most attention. Telerehabilitation is often coupled with self-management, and data collection is usually integrated with evaluation. The evidence of effectiveness of smartphone apps in self-management of LBP derived from RCTs are favourable on pain and disability for patients with chronic LBP 11 , 32 , 41 , 49 , 57 and patients after spinal surgery for LBP. 38 However, one RCT reported no effect of such interventions on pain, disability and beliefs of LBP patients but showed promising cost-utility results. 48 Overall, the quality of the analysed RCTs was moderate to good as assessed by the PEDro score. Indeed, the content of the interventions varied between the studies, and different apps presented differences in providing self-management. Nevertheless, improving physical activity level and providing education about LBP were the common components of the interventions. Self-management with a smartphone app was frequently used together with other interventions including face-to-face physical therapy, web-based education or email reminders. The systematic reviews focused on self-management actually reviewed app stores to find existing self-management apps rather than screening the scientific literature data 10 , 33 or included the studies focused more largely on eHealth interventions. 46 , 47 The effectiveness of the telerehabilitation interventions including smartphone apps evaluated by Dario et al. , in a 2017 systematic review showed moderate evidence that telerehabilitation is not more effective than minimal interventions for pain and disability outcomes. 40 However, since then, new RTCs have shown more optimistic results. 32 , 38 , 41 Telerehabilitation and self-management of LBP are in a phase of dynamic development; possibly favourable results in recent studies correspond to improvements in providing such interventions. Smartphone apps used as an evaluation tool showed good measurement proprieties for pain evaluation 23 – 26 and contradictory for spinal ROM measurements. 16 , 27 – 29 Indeed, technical aspects of such measurement are complicated: controlling all potential error sources in a multi-segmental movement is challenging. This observation is consistent with other spinal ROM measurement studies also indicating contradictory results. 61 , 62 Using the therapist's personal smartphone to perform measurements on patients may not be practical. However, remote clinical evaluation using a smartphone app should be developed regarding the consistent results between remote and face-to-face subgrouping of patients by treatment-based classification, the McKenzie system and the Backache Disability Index. 17 , 32 , 34 Use of smartphone apps for data collection seems highly useful and effective. Smartphones are personal and easily accessible to collect data. Many of the studies we found used smartphone apps to collect information, even if the main use was self-management, telerehabilitation, or evaluation. It seems pertinent to develop this branch of smartphone use. At the same time, it's important to respect data security considerations. Yet, our review also reveals development in data treatment. A recently started study implements machine learning technology to provide a personal adapted self-management strategy. 50 For this form of analysis, a large amount of data needs to be collected and smartphones perfectly fit this goal. Limitations Some articles could have been missed in our search strategy as we only used three databases. However, based on a large problem of our review, identifying the current fields of the smartphone apps use for LBP patients’ points out perspectives for further studies including perspectives for a more specific systematic review. Also, the highly heterogenic terminology regarding smartphone apps use could have resulted in some omissions. Several studies using eHealth strategy ( e.g. , tablet apps) were not included if there was no clear information about the smartphone app use. Conclusions The present scoping review revealed that the scientific literature interest in the utilization of smartphone apps for patients with LBP is notable. The main uses are for self-management, telerehabilitation, evaluation and data collection. Self-management is the most used in LBP and showed moderate- to good-quality evidence for effectiveness on pain and disability. Regarding technological and socio-cultural development, new fields of use may arise. Data availability Underlying data All data underlying the results are available as part of the article and no additional source data are required. Reporting guidelines Figshare: PRISMA-ScR checklist for ‘Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review’, https://doi.org/10.6084/m9.figshare.20555802.v1 . 63 Data are available under the terms of the Creative Commons Zero “No rights reserved” data waiver (CC0 1.0 Public domain dedication). Acknowledgements An earlier version of this article can be found on JMIR Preprints (doi: https://doi.org/10.2196/preprints.36225 ). References 1. Forecast number of mobile users worldwide 2019-2023. Statista. [cité 29 mars 2020]. Reference Source 2. Smartphone users worldwide 2020. Statista.[cité 30 mars 2020]. Reference Source 3. 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Publisher Full Text Comments on this article Comments (0) Version 2 VERSION 2 PUBLISHED 06 Sep 2022 ADD YOUR COMMENT Comment Author details Author details 1 UNH, INRAE, Université Clermont-Auvergne, Clermont-Ferrand, Puy de Dôme, 63000, France 2 Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, Puy de Dôme, 63118, France 3 Université Montpellier, Nimes, 30900, France 4 Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Nimes, Nimes, 30900, France Lech Dobija Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Validation, Visualization, Writing – Original Draft Preparation, Writing – Review & Editing Jean-Baptiste Lechauve Roles: Conceptualization, Data Curation, Formal Analysis, Methodology, Validation, Writing – Original Draft Preparation, Writing – Review & Editing Didier Mbony-Irankunda Roles: Formal Analysis, Methodology, Writing – Review & Editing Anne Plan-Paquet Roles: Conceptualization, Methodology, Supervision, Writing – Review & Editing Arnaud Dupeyron Roles: Conceptualization, Methodology, Supervision, Writing – Review & Editing Emmanuel Coudeyre Roles: Conceptualization, Formal Analysis, Funding Acquisition, Methodology, Supervision, Validation, Writing – Review & Editing Competing interests No competing interests were disclosed. Grant information This work was supported by Centre Hospitalier Universitaire de Clermont-Ferrand and Université Clermont Auvergne. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Article Versions (2) version 2 Revised Published: 07 May 2024, 11:1001 https://doi.org/10.12688/f1000research.123331.2 version 1 Published: 06 Sep 2022, 11:1001 https://doi.org/10.12688/f1000research.123331.1 Copyright © 2024 Dobija L et al . This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Download Export To Sciwheel Bibtex EndNote ProCite Ref. Manager (RIS) Sente metrics Views Downloads F1000Research - - PubMed Central info_outline Data from PMC are received and updated monthly. - - Citations open_in_new 0 open_in_new 0 open_in_new SEE MORE DETAILS CITE how to cite this article Dobija L, Lechauve JB, Mbony-Irankunda D et al. Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.12688/f1000research.123331.2 ) NOTE: If applicable, it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS track receive updates on this article Track an article to receive email alerts on any updates to this article. TRACK THIS ARTICLE Share Open Peer Review Current Reviewer Status: ? Key to Reviewer Statuses VIEW HIDE Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Version 2 VERSION 2 PUBLISHED 07 May 2024 Revised Views 0 Cite How to cite this report: Ulrich M. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.164960.r274858 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v2#referee-response-274858 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 05 Jun 2024 Marijn Ulrich , Utrecht University of Applied Science, Utrecht, The Netherlands Approved VIEWS 0 https://doi.org/10.5256/f1000research.164960.r274858 I agree with all of the changes you made in the article. Also with the improvements you made which did not directly address my concerns. I have no further concerns about your article. It has become a well written ... Continue reading READ ALL I agree with all of the changes you made in the article. Also with the improvements you made which did not directly address my concerns. I have no further concerns about your article. It has become a well written and interesting contribution to this field of research. Competing Interests: No competing interests were disclosed. Reviewer Expertise: My are of research is implementation of smartphone apps, or digital health, in the context of physiotherapy for people with low back pain. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Ulrich M. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.164960.r274858 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v2#referee-response-274858 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Roren A. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.164960.r274859 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v2#referee-response-274859 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 09 May 2024 Alexandra Roren , INSERM UMR-S 1153, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, PRES Sorbonne Paris Cité, ECaMO team, Institut Fédératif de Recherche sur le Handicap, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris, France Approved VIEWS 0 https://doi.org/10.5256/f1000research.164960.r274859 I approve this revised version. ... Continue reading READ ALL I approve this revised version. No further comments to make. Competing Interests: No competing interests were disclosed. Reviewer Expertise: Shoulder and trunk kinematics, development and assessment of innovative tools to assess and treat people whith chronic musculoskeletic disease, adhesion to treatment based on physical activity. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Roren A. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.164960.r274859 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v2#referee-response-274859 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Respond or Comment COMMENT ON THIS REPORT Version 1 VERSION 1 PUBLISHED 06 Sep 2022 Views 0 Cite How to cite this report: Ulrich M. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.135427.r253130 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v1#referee-response-253130 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 28 Mar 2024 Marijn Ulrich , Utrecht University of Applied Science, Utrecht, The Netherlands Approved with Reservations VIEWS 0 https://doi.org/10.5256/f1000research.135427.r253130 First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. The rationale and ... Continue reading READ ALL First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Are the rationale for, and objectives of, the Systematic Review clearly stated? Yes Are sufficient details of the methods and analysis provided to allow replication by others? Partly Is the statistical analysis and its interpretation appropriate? Not applicable Are the conclusions drawn adequately supported by the results presented in the review? Partly Competing Interests: No competing interests were disclosed. Reviewer Expertise: My are of research is implementation of smartphone apps, or digital health, in the context of physiotherapy for people with low back pain. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Ulrich M. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.135427.r253130 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v1#referee-response-253130 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 21 Jun 2024 Lech Dobija , Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, 63118, France 21 Jun 2024 Author Response Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope ... Continue reading Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). Author Response: Thank you for this pertinent remark. We have specified that exclusion criteria concerned only interventions for healthy people. “Similarly, we excluded studies in which the smartphone use involved healthy individuals for preventing LBP or promoting physical activity or a healthy lifestyle in healthy individuals.” Reviewer Comment: - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. Author Response: Thank you for pointing out the necessity of clarifying the inclusion of the study protocols articles. Indeed, we included all types of scientific articles including study protocols and RCT. At the time of conducting our literature research for the scoping review in May 2021, we included 6 study protocols. At this point, only one study has both its protocol and completed article published, and both have been included in our review. We adopted this approach for our scoping review to ensure comprehensive content analysis of the literature regarding the use of smartphone apps for patients with LBP. We clarified this in the Methods/Eligibility Criteria section: “In cases where both the protocol and the completed study article were published, we included both to ensure comprehensive content analysis of the literature on the subject.” Reviewer Comment: - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? Author Response: Thank you for this constructive remark. It is now specified in the text how we drew the conclusion. Conclusions section: “Based on the results of the included studies, we can conclude that there are promising findings regarding the use of smartphone apps for evaluation and data collection, but contradictory results regarding their use for measurements.” Reviewer Comment: This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Author Response: We acknowledge that the term 'promising' bears the characteristic of subjective judgment. We have now limited the employment of this term which is based on our assessment of the results presented in the included studies. This assessment is subject to biases, which are listed in the Limitations section. In the same time, we do not have any conflict of interest. We added some specifications to improve the clarity. Results section: “The results were promising, showed good compliance and patient-perceived utility. In addition, the authors noted good validity of an image-based quantification of pain-related disability. 44” “The presented eHealth strategy was not effective in improving patients’ back pain beliefs or decreasing disability or absenteeism, but the study provided a favourable cost-utility analysis. 48” “Irvine et al., showed that their mobile app FitBack was effective in improving physical, behavioural and worksite outcomes. FitBack was based on a self-tailored cognitive-behavioural approach and used the American Pain Society recommendations. 49” Discussion section: “Smartphone apps used as an evaluation tool showed good measurement proprieties for pain evaluation 23 – 26 and is contradictory for spinal ROM measurements. 16 , 27 – 29” “However, remote clinical evaluation using a smartphone app should be developed regarding the consistent results between remote and face-to-face of subgrouping of patients by treatment-based classification, the McKenzie system and the Backache Disability Index. 17 , 32 , 34” “Telerehabilitation and self-management of LBP are in a phase of dynamic development; possibly favourable results in recent studies correspond to improvements in providing such interventions.” Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). Author Response: Thank you for this pertinent remark. We have specified that exclusion criteria concerned only interventions for healthy people. “Similarly, we excluded studies in which the smartphone use involved healthy individuals for preventing LBP or promoting physical activity or a healthy lifestyle in healthy individuals.” Reviewer Comment: - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. Author Response: Thank you for pointing out the necessity of clarifying the inclusion of the study protocols articles. Indeed, we included all types of scientific articles including study protocols and RCT. At the time of conducting our literature research for the scoping review in May 2021, we included 6 study protocols. At this point, only one study has both its protocol and completed article published, and both have been included in our review. We adopted this approach for our scoping review to ensure comprehensive content analysis of the literature regarding the use of smartphone apps for patients with LBP. We clarified this in the Methods/Eligibility Criteria section: “In cases where both the protocol and the completed study article were published, we included both to ensure comprehensive content analysis of the literature on the subject.” Reviewer Comment: - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? Author Response: Thank you for this constructive remark. It is now specified in the text how we drew the conclusion. Conclusions section: “Based on the results of the included studies, we can conclude that there are promising findings regarding the use of smartphone apps for evaluation and data collection, but contradictory results regarding their use for measurements.” Reviewer Comment: This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Author Response: We acknowledge that the term 'promising' bears the characteristic of subjective judgment. We have now limited the employment of this term which is based on our assessment of the results presented in the included studies. This assessment is subject to biases, which are listed in the Limitations section. In the same time, we do not have any conflict of interest. We added some specifications to improve the clarity. Results section: “The results were promising, showed good compliance and patient-perceived utility. In addition, the authors noted good validity of an image-based quantification of pain-related disability. 44” “The presented eHealth strategy was not effective in improving patients’ back pain beliefs or decreasing disability or absenteeism, but the study provided a favourable cost-utility analysis. 48” “Irvine et al., showed that their mobile app FitBack was effective in improving physical, behavioural and worksite outcomes. FitBack was based on a self-tailored cognitive-behavioural approach and used the American Pain Society recommendations. 49” Discussion section: “Smartphone apps used as an evaluation tool showed good measurement proprieties for pain evaluation 23 – 26 and is contradictory for spinal ROM measurements. 16 , 27 – 29” “However, remote clinical evaluation using a smartphone app should be developed regarding the consistent results between remote and face-to-face of subgrouping of patients by treatment-based classification, the McKenzie system and the Backache Disability Index. 17 , 32 , 34” “Telerehabilitation and self-management of LBP are in a phase of dynamic development; possibly favourable results in recent studies correspond to improvements in providing such interventions.” Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 21 Jun 2024 Lech Dobija , Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, 63118, France 21 Jun 2024 Author Response Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope ... Continue reading Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). Author Response: Thank you for this pertinent remark. We have specified that exclusion criteria concerned only interventions for healthy people. “Similarly, we excluded studies in which the smartphone use involved healthy individuals for preventing LBP or promoting physical activity or a healthy lifestyle in healthy individuals.” Reviewer Comment: - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. Author Response: Thank you for pointing out the necessity of clarifying the inclusion of the study protocols articles. Indeed, we included all types of scientific articles including study protocols and RCT. At the time of conducting our literature research for the scoping review in May 2021, we included 6 study protocols. At this point, only one study has both its protocol and completed article published, and both have been included in our review. We adopted this approach for our scoping review to ensure comprehensive content analysis of the literature regarding the use of smartphone apps for patients with LBP. We clarified this in the Methods/Eligibility Criteria section: “In cases where both the protocol and the completed study article were published, we included both to ensure comprehensive content analysis of the literature on the subject.” Reviewer Comment: - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? Author Response: Thank you for this constructive remark. It is now specified in the text how we drew the conclusion. Conclusions section: “Based on the results of the included studies, we can conclude that there are promising findings regarding the use of smartphone apps for evaluation and data collection, but contradictory results regarding their use for measurements.” Reviewer Comment: This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Author Response: We acknowledge that the term 'promising' bears the characteristic of subjective judgment. We have now limited the employment of this term which is based on our assessment of the results presented in the included studies. This assessment is subject to biases, which are listed in the Limitations section. In the same time, we do not have any conflict of interest. We added some specifications to improve the clarity. Results section: “The results were promising, showed good compliance and patient-perceived utility. In addition, the authors noted good validity of an image-based quantification of pain-related disability. 44” “The presented eHealth strategy was not effective in improving patients’ back pain beliefs or decreasing disability or absenteeism, but the study provided a favourable cost-utility analysis. 48” “Irvine et al., showed that their mobile app FitBack was effective in improving physical, behavioural and worksite outcomes. FitBack was based on a self-tailored cognitive-behavioural approach and used the American Pain Society recommendations. 49” Discussion section: “Smartphone apps used as an evaluation tool showed good measurement proprieties for pain evaluation 23 – 26 and is contradictory for spinal ROM measurements. 16 , 27 – 29” “However, remote clinical evaluation using a smartphone app should be developed regarding the consistent results between remote and face-to-face of subgrouping of patients by treatment-based classification, the McKenzie system and the Backache Disability Index. 17 , 32 , 34” “Telerehabilitation and self-management of LBP are in a phase of dynamic development; possibly favourable results in recent studies correspond to improvements in providing such interventions.” Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). Author Response: Thank you for this pertinent remark. We have specified that exclusion criteria concerned only interventions for healthy people. “Similarly, we excluded studies in which the smartphone use involved healthy individuals for preventing LBP or promoting physical activity or a healthy lifestyle in healthy individuals.” Reviewer Comment: - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. Author Response: Thank you for pointing out the necessity of clarifying the inclusion of the study protocols articles. Indeed, we included all types of scientific articles including study protocols and RCT. At the time of conducting our literature research for the scoping review in May 2021, we included 6 study protocols. At this point, only one study has both its protocol and completed article published, and both have been included in our review. We adopted this approach for our scoping review to ensure comprehensive content analysis of the literature regarding the use of smartphone apps for patients with LBP. We clarified this in the Methods/Eligibility Criteria section: “In cases where both the protocol and the completed study article were published, we included both to ensure comprehensive content analysis of the literature on the subject.” Reviewer Comment: - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? Author Response: Thank you for this constructive remark. It is now specified in the text how we drew the conclusion. Conclusions section: “Based on the results of the included studies, we can conclude that there are promising findings regarding the use of smartphone apps for evaluation and data collection, but contradictory results regarding their use for measurements.” Reviewer Comment: This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Author Response: We acknowledge that the term 'promising' bears the characteristic of subjective judgment. We have now limited the employment of this term which is based on our assessment of the results presented in the included studies. This assessment is subject to biases, which are listed in the Limitations section. In the same time, we do not have any conflict of interest. We added some specifications to improve the clarity. Results section: “The results were promising, showed good compliance and patient-perceived utility. In addition, the authors noted good validity of an image-based quantification of pain-related disability. 44” “The presented eHealth strategy was not effective in improving patients’ back pain beliefs or decreasing disability or absenteeism, but the study provided a favourable cost-utility analysis. 48” “Irvine et al., showed that their mobile app FitBack was effective in improving physical, behavioural and worksite outcomes. FitBack was based on a self-tailored cognitive-behavioural approach and used the American Pain Society recommendations. 49” Discussion section: “Smartphone apps used as an evaluation tool showed good measurement proprieties for pain evaluation 23 – 26 and is contradictory for spinal ROM measurements. 16 , 27 – 29” “However, remote clinical evaluation using a smartphone app should be developed regarding the consistent results between remote and face-to-face of subgrouping of patients by treatment-based classification, the McKenzie system and the Backache Disability Index. 17 , 32 , 34” “Telerehabilitation and self-management of LBP are in a phase of dynamic development; possibly favourable results in recent studies correspond to improvements in providing such interventions.” Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Views 0 Cite How to cite this report: Roren A. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.135427.r152995 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v1#referee-response-152995 NOTE: it is important to ensure the information in square brackets after the title is included in this citation. Close Copy Citation Details Reviewer Report 24 Oct 2022 Alexandra Roren , INSERM UMR-S 1153, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, PRES Sorbonne Paris Cité, ECaMO team, Institut Fédératif de Recherche sur le Handicap, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris, France Approved VIEWS 0 https://doi.org/10.5256/f1000research.135427.r152995 This scoping review is well written. It's an interesting work that takes stock of a current topic. My minor remarks are the following: Abstract: Background - There is a gap ... Continue reading READ ALL This scoping review is well written. It's an interesting work that takes stock of a current topic. My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Fourth paragraph, first sentence: Does the "purpose" include overtreating? You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Methods Could you justify why you included studies from January 1st, 2005? Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. It's not clear why you use both the words "efficacy" and "effectiveness". Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. When you are talking of efficacy or effectiveness, specify systematically on what outcomes. I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Last paragraph before the limits part, what about data security? Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Conclusions: Same remark about "growing literature". Are the rationale for, and objectives of, the Systematic Review clearly stated? Yes Are sufficient details of the methods and analysis provided to allow replication by others? Yes Is the statistical analysis and its interpretation appropriate? Not applicable Are the conclusions drawn adequately supported by the results presented in the review? Yes Competing Interests: No competing interests were disclosed. Reviewer Expertise: Shoulder and trunk kinematics, development and assessment of innovative tools to assess and treat people whith chronic musculoskeletic disease, adhesion to treatment based on physical activity. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. Close READ LESS CITE CITE HOW TO CITE THIS REPORT Roren A. Reviewer Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.135427.r152995 ) The direct URL for this report is: https://f1000research.com/articles/11-1001/v1#referee-response-152995 NOTE: it is important to ensure the information in square brackets after the title is included in all citations of this article. COPY CITATION DETAILS Report a concern Author Response 21 Jun 2024 Lech Dobija , Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, 63118, France 21 Jun 2024 Author Response Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time ... Continue reading Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Author Response: Thank you for this remark. We have removed the first sentence from abstract. Reviewer Comment: Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Author Response: We acknowledge that we did not conduct a quantitative assessment of studies over the years. We have changed this sentence: “This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients.” Reviewer Comment: Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Author Response: We have reformulate this sentence: “Extensive software of smartphones has permitted the development of new applications, allowing video communication, social media consulting, gaming, and navigation.” Reviewer Comment: Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Author Response: Thank you for this pertinent remark. We have added the specifications about chronic LBP: “When nonspecific LBP persists and becomes chronic, it becomes increasingly complex and challenging to manage due to its multifactorial nature.” “Current guidelines for management of chronic LBP include psychosocial interventions along with exercise therapy, medications, multidisciplinary rehabilitation and spinal manipulation. 8 ” Reviewer Comment: Fourth paragraph, first sentence: Does the "purpose" include overtreating? Author Response: Thank you for this comment. We mentioned overtreating (which is not the purpose of the review) to introduce the rationale for self-management strategies for chronic LBP. Reviewer Comment: You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Author Response: Thank you very much for this constructive remark. We added this aspect to Introduction: “Compared to face-to-face treatment smartphone apps could potentially be more cost-effective and could help to overcome the problem of healthcare accessibility.” Reviewer Comment: Methods Could you justify why you included studies from January 1st, 2005? Author Response: We added the justification: “This time frame includes the emergence of the new generation of mobile phones.” Reviewer Comment: Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. Author Response: We added the sentence about PainMAP app: “Considering pain evaluation, PainMAP showed excellent intra- and inter-rater reliability and good validity for quantifying the number of pain sites and pain area. 23 This application allows patients to mark their pain on digital body charts and automatically quantifies such self-assessment. Furthermore, another smartphone app could effectively evaluate pain changes after transcutaneous electrical nerve stimulation. 25 ” Reviewer Comment: When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Author Response: Thank you for this remark. We added this specification: “Hou et al., evaluated a system of telerehabilitation based on a smartphone app interface for patients after lumbar surgery for LBP and a web-based interface for physicians providing and surveying rehabilitation and communicating with the patient.” “The evidence of effectiveness of smartphone apps in self-management of LBP derived from RCTs are favourable on pain and disability for patients with chronic LBP 11 , 32 , 41 , 49 , 57 and patients after spinal surgery for LBP. 38 ” Reviewer Comment: Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. Author Response: Thank you. We applied your suggestion: “The present review did not aim to firmly classify use of the smartphone apps, as their multiple uses can be controversial.” Reviewer Comment: It's not clear why you use both the words "efficacy" and "effectiveness". Author Response: Thank you for this pertinent remark. We have uniformed the words use trough manuscript. Reviewer Comment: Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. Author Response: We have changed this sentence: “We observed a notable interest in scientific literature regarding the utilization of smartphone apps for patients with LBP.” Reviewer Comment: When you are talking of efficacy or effectiveness, specify systematically on what outcomes. Author Response: Thank you for this remark. In the objective of the present scoping review, we did not specify the outcome of effectiveness, in contrast to what would be appropriate for a systematic review. Our intention was to conduct evaluation of the content of scientific literature including all types of studies and including the effectiveness regarding all types of outcomes. However, we agree that specifying the outcome for effectiveness of the studies we reported would improve the clarity. We added the outcomes when reporting effectiveness through the manuscript. Reviewer Comment: I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Author Response: We have reformulated this sentence: “Using the therapist's personal smartphone to perform measurements on patients may not be practical.” Reviewer Comment: Last paragraph before the limits part, what about data security? Author Response: Thank you for this important remark. We added a sentence about it: “At the same time, it's important to respect data security considerations.” Reviewer Comment: Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Author Response: We removed the part of paragraph referred to smartphone addiction and compulsive behaviour. Reviewer Comment: Conclusions: Same remark about "growing literature". Author Response: We have reformulated the sentence: “The present scoping review revealed that the scientific literature interest in the utilization of smartphone apps for patients with LBP is notable.” Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Author Response: Thank you for this remark. We have removed the first sentence from abstract. Reviewer Comment: Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Author Response: We acknowledge that we did not conduct a quantitative assessment of studies over the years. We have changed this sentence: “This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients.” Reviewer Comment: Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Author Response: We have reformulate this sentence: “Extensive software of smartphones has permitted the development of new applications, allowing video communication, social media consulting, gaming, and navigation.” Reviewer Comment: Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Author Response: Thank you for this pertinent remark. We have added the specifications about chronic LBP: “When nonspecific LBP persists and becomes chronic, it becomes increasingly complex and challenging to manage due to its multifactorial nature.” “Current guidelines for management of chronic LBP include psychosocial interventions along with exercise therapy, medications, multidisciplinary rehabilitation and spinal manipulation. 8 ” Reviewer Comment: Fourth paragraph, first sentence: Does the "purpose" include overtreating? Author Response: Thank you for this comment. We mentioned overtreating (which is not the purpose of the review) to introduce the rationale for self-management strategies for chronic LBP. Reviewer Comment: You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Author Response: Thank you very much for this constructive remark. We added this aspect to Introduction: “Compared to face-to-face treatment smartphone apps could potentially be more cost-effective and could help to overcome the problem of healthcare accessibility.” Reviewer Comment: Methods Could you justify why you included studies from January 1st, 2005? Author Response: We added the justification: “This time frame includes the emergence of the new generation of mobile phones.” Reviewer Comment: Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. Author Response: We added the sentence about PainMAP app: “Considering pain evaluation, PainMAP showed excellent intra- and inter-rater reliability and good validity for quantifying the number of pain sites and pain area. 23 This application allows patients to mark their pain on digital body charts and automatically quantifies such self-assessment. Furthermore, another smartphone app could effectively evaluate pain changes after transcutaneous electrical nerve stimulation. 25 ” Reviewer Comment: When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Author Response: Thank you for this remark. We added this specification: “Hou et al., evaluated a system of telerehabilitation based on a smartphone app interface for patients after lumbar surgery for LBP and a web-based interface for physicians providing and surveying rehabilitation and communicating with the patient.” “The evidence of effectiveness of smartphone apps in self-management of LBP derived from RCTs are favourable on pain and disability for patients with chronic LBP 11 , 32 , 41 , 49 , 57 and patients after spinal surgery for LBP. 38 ” Reviewer Comment: Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. Author Response: Thank you. We applied your suggestion: “The present review did not aim to firmly classify use of the smartphone apps, as their multiple uses can be controversial.” Reviewer Comment: It's not clear why you use both the words "efficacy" and "effectiveness". Author Response: Thank you for this pertinent remark. We have uniformed the words use trough manuscript. Reviewer Comment: Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. Author Response: We have changed this sentence: “We observed a notable interest in scientific literature regarding the utilization of smartphone apps for patients with LBP.” Reviewer Comment: When you are talking of efficacy or effectiveness, specify systematically on what outcomes. Author Response: Thank you for this remark. In the objective of the present scoping review, we did not specify the outcome of effectiveness, in contrast to what would be appropriate for a systematic review. Our intention was to conduct evaluation of the content of scientific literature including all types of studies and including the effectiveness regarding all types of outcomes. However, we agree that specifying the outcome for effectiveness of the studies we reported would improve the clarity. We added the outcomes when reporting effectiveness through the manuscript. Reviewer Comment: I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Author Response: We have reformulated this sentence: “Using the therapist's personal smartphone to perform measurements on patients may not be practical.” Reviewer Comment: Last paragraph before the limits part, what about data security? Author Response: Thank you for this important remark. We added a sentence about it: “At the same time, it's important to respect data security considerations.” Reviewer Comment: Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Author Response: We removed the part of paragraph referred to smartphone addiction and compulsive behaviour. Reviewer Comment: Conclusions: Same remark about "growing literature". Author Response: We have reformulated the sentence: “The present scoping review revealed that the scientific literature interest in the utilization of smartphone apps for patients with LBP is notable.” Competing Interests: No competing interests were disclosed. Close Report a concern Respond or Comment COMMENTS ON THIS REPORT Author Response 21 Jun 2024 Lech Dobija , Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, 63118, France 21 Jun 2024 Author Response Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time ... Continue reading Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Author Response: Thank you for this remark. We have removed the first sentence from abstract. Reviewer Comment: Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Author Response: We acknowledge that we did not conduct a quantitative assessment of studies over the years. We have changed this sentence: “This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients.” Reviewer Comment: Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Author Response: We have reformulate this sentence: “Extensive software of smartphones has permitted the development of new applications, allowing video communication, social media consulting, gaming, and navigation.” Reviewer Comment: Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Author Response: Thank you for this pertinent remark. We have added the specifications about chronic LBP: “When nonspecific LBP persists and becomes chronic, it becomes increasingly complex and challenging to manage due to its multifactorial nature.” “Current guidelines for management of chronic LBP include psychosocial interventions along with exercise therapy, medications, multidisciplinary rehabilitation and spinal manipulation. 8 ” Reviewer Comment: Fourth paragraph, first sentence: Does the "purpose" include overtreating? Author Response: Thank you for this comment. We mentioned overtreating (which is not the purpose of the review) to introduce the rationale for self-management strategies for chronic LBP. Reviewer Comment: You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Author Response: Thank you very much for this constructive remark. We added this aspect to Introduction: “Compared to face-to-face treatment smartphone apps could potentially be more cost-effective and could help to overcome the problem of healthcare accessibility.” Reviewer Comment: Methods Could you justify why you included studies from January 1st, 2005? Author Response: We added the justification: “This time frame includes the emergence of the new generation of mobile phones.” Reviewer Comment: Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. Author Response: We added the sentence about PainMAP app: “Considering pain evaluation, PainMAP showed excellent intra- and inter-rater reliability and good validity for quantifying the number of pain sites and pain area. 23 This application allows patients to mark their pain on digital body charts and automatically quantifies such self-assessment. Furthermore, another smartphone app could effectively evaluate pain changes after transcutaneous electrical nerve stimulation. 25 ” Reviewer Comment: When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Author Response: Thank you for this remark. We added this specification: “Hou et al., evaluated a system of telerehabilitation based on a smartphone app interface for patients after lumbar surgery for LBP and a web-based interface for physicians providing and surveying rehabilitation and communicating with the patient.” “The evidence of effectiveness of smartphone apps in self-management of LBP derived from RCTs are favourable on pain and disability for patients with chronic LBP 11 , 32 , 41 , 49 , 57 and patients after spinal surgery for LBP. 38 ” Reviewer Comment: Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. Author Response: Thank you. We applied your suggestion: “The present review did not aim to firmly classify use of the smartphone apps, as their multiple uses can be controversial.” Reviewer Comment: It's not clear why you use both the words "efficacy" and "effectiveness". Author Response: Thank you for this pertinent remark. We have uniformed the words use trough manuscript. Reviewer Comment: Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. Author Response: We have changed this sentence: “We observed a notable interest in scientific literature regarding the utilization of smartphone apps for patients with LBP.” Reviewer Comment: When you are talking of efficacy or effectiveness, specify systematically on what outcomes. Author Response: Thank you for this remark. In the objective of the present scoping review, we did not specify the outcome of effectiveness, in contrast to what would be appropriate for a systematic review. Our intention was to conduct evaluation of the content of scientific literature including all types of studies and including the effectiveness regarding all types of outcomes. However, we agree that specifying the outcome for effectiveness of the studies we reported would improve the clarity. We added the outcomes when reporting effectiveness through the manuscript. Reviewer Comment: I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Author Response: We have reformulated this sentence: “Using the therapist's personal smartphone to perform measurements on patients may not be practical.” Reviewer Comment: Last paragraph before the limits part, what about data security? Author Response: Thank you for this important remark. We added a sentence about it: “At the same time, it's important to respect data security considerations.” Reviewer Comment: Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Author Response: We removed the part of paragraph referred to smartphone addiction and compulsive behaviour. Reviewer Comment: Conclusions: Same remark about "growing literature". Author Response: We have reformulated the sentence: “The present scoping review revealed that the scientific literature interest in the utilization of smartphone apps for patients with LBP is notable.” Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Author Response: Thank you for this remark. We have removed the first sentence from abstract. Reviewer Comment: Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Author Response: We acknowledge that we did not conduct a quantitative assessment of studies over the years. We have changed this sentence: “This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients.” Reviewer Comment: Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Author Response: We have reformulate this sentence: “Extensive software of smartphones has permitted the development of new applications, allowing video communication, social media consulting, gaming, and navigation.” Reviewer Comment: Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Author Response: Thank you for this pertinent remark. We have added the specifications about chronic LBP: “When nonspecific LBP persists and becomes chronic, it becomes increasingly complex and challenging to manage due to its multifactorial nature.” “Current guidelines for management of chronic LBP include psychosocial interventions along with exercise therapy, medications, multidisciplinary rehabilitation and spinal manipulation. 8 ” Reviewer Comment: Fourth paragraph, first sentence: Does the "purpose" include overtreating? Author Response: Thank you for this comment. We mentioned overtreating (which is not the purpose of the review) to introduce the rationale for self-management strategies for chronic LBP. Reviewer Comment: You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Author Response: Thank you very much for this constructive remark. We added this aspect to Introduction: “Compared to face-to-face treatment smartphone apps could potentially be more cost-effective and could help to overcome the problem of healthcare accessibility.” Reviewer Comment: Methods Could you justify why you included studies from January 1st, 2005? Author Response: We added the justification: “This time frame includes the emergence of the new generation of mobile phones.” Reviewer Comment: Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. Author Response: We added the sentence about PainMAP app: “Considering pain evaluation, PainMAP showed excellent intra- and inter-rater reliability and good validity for quantifying the number of pain sites and pain area. 23 This application allows patients to mark their pain on digital body charts and automatically quantifies such self-assessment. Furthermore, another smartphone app could effectively evaluate pain changes after transcutaneous electrical nerve stimulation. 25 ” Reviewer Comment: When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Author Response: Thank you for this remark. We added this specification: “Hou et al., evaluated a system of telerehabilitation based on a smartphone app interface for patients after lumbar surgery for LBP and a web-based interface for physicians providing and surveying rehabilitation and communicating with the patient.” “The evidence of effectiveness of smartphone apps in self-management of LBP derived from RCTs are favourable on pain and disability for patients with chronic LBP 11 , 32 , 41 , 49 , 57 and patients after spinal surgery for LBP. 38 ” Reviewer Comment: Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. Author Response: Thank you. We applied your suggestion: “The present review did not aim to firmly classify use of the smartphone apps, as their multiple uses can be controversial.” Reviewer Comment: It's not clear why you use both the words "efficacy" and "effectiveness". Author Response: Thank you for this pertinent remark. We have uniformed the words use trough manuscript. Reviewer Comment: Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. Author Response: We have changed this sentence: “We observed a notable interest in scientific literature regarding the utilization of smartphone apps for patients with LBP.” Reviewer Comment: When you are talking of efficacy or effectiveness, specify systematically on what outcomes. Author Response: Thank you for this remark. In the objective of the present scoping review, we did not specify the outcome of effectiveness, in contrast to what would be appropriate for a systematic review. Our intention was to conduct evaluation of the content of scientific literature including all types of studies and including the effectiveness regarding all types of outcomes. However, we agree that specifying the outcome for effectiveness of the studies we reported would improve the clarity. We added the outcomes when reporting effectiveness through the manuscript. Reviewer Comment: I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Author Response: We have reformulated this sentence: “Using the therapist's personal smartphone to perform measurements on patients may not be practical.” Reviewer Comment: Last paragraph before the limits part, what about data security? Author Response: Thank you for this important remark. We added a sentence about it: “At the same time, it's important to respect data security considerations.” Reviewer Comment: Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Author Response: We removed the part of paragraph referred to smartphone addiction and compulsive behaviour. Reviewer Comment: Conclusions: Same remark about "growing literature". Author Response: We have reformulated the sentence: “The present scoping review revealed that the scientific literature interest in the utilization of smartphone apps for patients with LBP is notable.” Competing Interests: No competing interests were disclosed. Close Report a concern COMMENT ON THIS REPORT Comments on this article Comments (0) Version 2 VERSION 2 PUBLISHED 06 Sep 2022 ADD YOUR COMMENT Comment keyboard_arrow_left keyboard_arrow_right Open Peer Review Reviewer Status info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions Reviewer Reports Invited Reviewers 1 2 Version 2 (revision) 07 May 24 read read Version 1 06 Sep 22 read read Alexandra Roren , Université Paris Descartes, Paris, France Marijn Ulrich , Utrecht University of Applied Science, Utrecht, The Netherlands Comments on this article All Comments (0) Add a comment Sign up for content alerts Sign Up You are now signed up to receive this alert Browse by related subjects keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Ulrich M. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 05 Jun 2024 | for Version 2 Marijn Ulrich , Utrecht University of Applied Science, Utrecht, The Netherlands 0 Views copyright © 2024 Ulrich M. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions I agree with all of the changes you made in the article. Also with the improvements you made which did not directly address my concerns. I have no further concerns about your article. It has become a well written and interesting contribution to this field of research. Competing Interests No competing interests were disclosed. Reviewer Expertise My are of research is implementation of smartphone apps, or digital health, in the context of physiotherapy for people with low back pain. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (0) Ulrich M. Peer Review Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.164960.r274858) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1001/v2#referee-response-274858 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Roren A. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 09 May 2024 | for Version 2 Alexandra Roren , INSERM UMR-S 1153, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, PRES Sorbonne Paris Cité, ECaMO team, Institut Fédératif de Recherche sur le Handicap, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris, France 0 Views copyright © 2024 Roren A. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (0) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions I approve this revised version. No further comments to make. Competing Interests No competing interests were disclosed. Reviewer Expertise Shoulder and trunk kinematics, development and assessment of innovative tools to assess and treat people whith chronic musculoskeletic disease, adhesion to treatment based on physical activity. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (0) Roren A. Peer Review Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.164960.r274859) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1001/v2#referee-response-274859 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2024 Ulrich M. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 28 Mar 2024 | for Version 1 Marijn Ulrich , Utrecht University of Applied Science, Utrecht, The Netherlands 0 Views copyright © 2024 Ulrich M. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Approved With Reservations info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Are the rationale for, and objectives of, the Systematic Review clearly stated? Yes Are sufficient details of the methods and analysis provided to allow replication by others? Partly Is the statistical analysis and its interpretation appropriate? Not applicable Are the conclusions drawn adequately supported by the results presented in the review? Partly Competing Interests No competing interests were disclosed. Reviewer Expertise My are of research is implementation of smartphone apps, or digital health, in the context of physiotherapy for people with low back pain. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard, however I have significant reservations, as outlined above. reply Respond to this report Responses (1) Author Response 21 Jun 2024 Lech Dobija, Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, 63118, France Reviewer Comment: First of all, I would like to complement the authors on this clearly written and relevant scoping review. It's nice to read a review with a broader scope than just evidence of treatment effect. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: The rationale and objectives of the study are clear for me. The introduction gives good context on the topic. The methods used are quite clear and repeatable, but with some remarks: - In the exclusion criteria, it's not fully clear if you also excluded physical activity promotion or lifestyle advise for people with low back pain (or only for healthy people). Author Response: Thank you for this pertinent remark. We have specified that exclusion criteria concerned only interventions for healthy people. “Similarly, we excluded studies in which the smartphone use involved healthy individuals for preventing LBP or promoting physical activity or a healthy lifestyle in healthy individuals.” Reviewer Comment: - You included study protocols, but what did you do when those studies were performed and published? Since they can describe the exact same study, can you mention if you excluded protocols when the article of the finished study was published for example. Or any other way of handling them if you included them both. Author Response: Thank you for pointing out the necessity of clarifying the inclusion of the study protocols articles. Indeed, we included all types of scientific articles including study protocols and RCT. At the time of conducting our literature research for the scoping review in May 2021, we included 6 study protocols. At this point, only one study has both its protocol and completed article published, and both have been included in our review. We adopted this approach for our scoping review to ensure comprehensive content analysis of the literature regarding the use of smartphone apps for patients with LBP. We clarified this in the Methods/Eligibility Criteria section: “In cases where both the protocol and the completed study article were published, we included both to ensure comprehensive content analysis of the literature on the subject.” Reviewer Comment: - In the synthesis, can you explain how you drew conclusions like 'promising'. Did you draw those conclusions yourselves or did you take (copy-paste) these conclusions from the included article (like you do mention in table 2 under 'author's conclusion')? Author Response: Thank you for this constructive remark. It is now specified in the text how we drew the conclusion. Conclusions section: “Based on the results of the included studies, we can conclude that there are promising findings regarding the use of smartphone apps for evaluation and data collection, but contradictory results regarding their use for measurements.” Reviewer Comment: This last point applies for the results and discussion/conclusion as well. Quite often you use conclusions like 'promising'. To me, it's too subjective (and perhaps biased). It would be nice if you can give some clarity on that. I understand it's not the main goal like in a systematic review or meta-analysis. Author Response: We acknowledge that the term 'promising' bears the characteristic of subjective judgment. We have now limited the employment of this term which is based on our assessment of the results presented in the included studies. This assessment is subject to biases, which are listed in the Limitations section. In the same time, we do not have any conflict of interest. We added some specifications to improve the clarity. Results section: “The results were promising, showed good compliance and patient-perceived utility. In addition, the authors noted good validity of an image-based quantification of pain-related disability. 44” “The presented eHealth strategy was not effective in improving patients’ back pain beliefs or decreasing disability or absenteeism, but the study provided a favourable cost-utility analysis. 48” “Irvine et al., showed that their mobile app FitBack was effective in improving physical, behavioural and worksite outcomes. FitBack was based on a self-tailored cognitive-behavioural approach and used the American Pain Society recommendations. 49” Discussion section: “Smartphone apps used as an evaluation tool showed good measurement proprieties for pain evaluation 23 – 26 and is contradictory for spinal ROM measurements. 16 , 27 – 29” “However, remote clinical evaluation using a smartphone app should be developed regarding the consistent results between remote and face-to-face of subgrouping of patients by treatment-based classification, the McKenzie system and the Backache Disability Index. 17 , 32 , 34” “Telerehabilitation and self-management of LBP are in a phase of dynamic development; possibly favourable results in recent studies correspond to improvements in providing such interventions.” View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Ulrich M. Peer Review Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.135427.r253130) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1001/v1#referee-response-253130 keyboard_arrow_left Back to all reports Reviewer Report 0 Views copyright © 2022 Roren A. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 24 Oct 2022 | for Version 1 Alexandra Roren , INSERM UMR-S 1153, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, PRES Sorbonne Paris Cité, ECaMO team, Institut Fédératif de Recherche sur le Handicap, Hôpital Cochin, AP-HP, Université Paris Descartes, Paris, France 0 Views copyright © 2022 Roren A. This is an open access peer review report distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. format_quote Cite this report speaker_notes Responses (1) Approved info_outline Alongside their report, reviewers assign a status to the article: Approved The paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved Fundamental flaws in the paper seriously undermine the findings and conclusions This scoping review is well written. It's an interesting work that takes stock of a current topic. My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Fourth paragraph, first sentence: Does the "purpose" include overtreating? You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Methods Could you justify why you included studies from January 1st, 2005? Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. It's not clear why you use both the words "efficacy" and "effectiveness". Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. When you are talking of efficacy or effectiveness, specify systematically on what outcomes. I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Last paragraph before the limits part, what about data security? Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Conclusions: Same remark about "growing literature". Are the rationale for, and objectives of, the Systematic Review clearly stated? Yes Are sufficient details of the methods and analysis provided to allow replication by others? Yes Is the statistical analysis and its interpretation appropriate? Not applicable Are the conclusions drawn adequately supported by the results presented in the review? Yes Competing Interests No competing interests were disclosed. Reviewer Expertise Shoulder and trunk kinematics, development and assessment of innovative tools to assess and treat people whith chronic musculoskeletic disease, adhesion to treatment based on physical activity. I confirm that I have read this submission and believe that I have an appropriate level of expertise to confirm that it is of an acceptable scientific standard. reply Respond to this report Responses (1) Author Response 21 Jun 2024 Lech Dobija, Service de Médecine Physique et de Réadaptation, Centre Hospitalo-Universitaire (CHU) de Clermont Ferrand, Cébazat, 63118, France Reviewer Comment: This scoping review is well written. It's an interesting work that takes stock of a current topic. Author Response: Thank you very much for taking the time to review my manuscript and for your precious constructive comments. Reviewer Comment: My minor remarks are the following: Abstract: Background - There is a gap between the first (too general) and second sentences. Author Response: Thank you for this remark. We have removed the first sentence from abstract. Reviewer Comment: Conclusions - You can't state the growing literature as you didn't really study this aspect (quantitative assessment of studies through the years). Author Response: We acknowledge that we did not conduct a quantitative assessment of studies over the years. We have changed this sentence: “This scoping review revealed a notable interest in the scientific literatures regarding the use of smartphone apps for LBP patients.” Reviewer Comment: Introduction: First paragraph: Are "Navigation, video communication, gaming, and social media" the most common use of mobile phones? Author Response: We have reformulate this sentence: “Extensive software of smartphones has permitted the development of new applications, allowing video communication, social media consulting, gaming, and navigation.” Reviewer Comment: Third paragraph: You should make a difference between LBP and chronic LBP which is in some conditions the major target of biopsychosocial management. Author Response: Thank you for this pertinent remark. We have added the specifications about chronic LBP: “When nonspecific LBP persists and becomes chronic, it becomes increasingly complex and challenging to manage due to its multifactorial nature.” “Current guidelines for management of chronic LBP include psychosocial interventions along with exercise therapy, medications, multidisciplinary rehabilitation and spinal manipulation. 8 ” Reviewer Comment: Fourth paragraph, first sentence: Does the "purpose" include overtreating? Author Response: Thank you for this comment. We mentioned overtreating (which is not the purpose of the review) to introduce the rationale for self-management strategies for chronic LBP. Reviewer Comment: You could also raise the topic of the cost and accessibility of the apps compared to usual (face-to-face) treatment. Author Response: Thank you very much for this constructive remark. We added this aspect to Introduction: “Compared to face-to-face treatment smartphone apps could potentially be more cost-effective and could help to overcome the problem of healthcare accessibility.” Reviewer Comment: Methods Could you justify why you included studies from January 1st, 2005? Author Response: We added the justification: “This time frame includes the emergence of the new generation of mobile phones.” Reviewer Comment: Results: Use of smartphone apps for evaluation: Give a few words about PainMAP. Author Response: We added the sentence about PainMAP app: “Considering pain evaluation, PainMAP showed excellent intra- and inter-rater reliability and good validity for quantifying the number of pain sites and pain area. 23 This application allows patients to mark their pain on digital body charts and automatically quantifies such self-assessment. Furthermore, another smartphone app could effectively evaluate pain changes after transcutaneous electrical nerve stimulation. 25 ” Reviewer Comment: When you talk about spine surgery, specify that you are talking of "spine surgery" for low back pain. Author Response: Thank you for this remark. We added this specification: “Hou et al., evaluated a system of telerehabilitation based on a smartphone app interface for patients after lumbar surgery for LBP and a web-based interface for physicians providing and surveying rehabilitation and communicating with the patient.” “The evidence of effectiveness of smartphone apps in self-management of LBP derived from RCTs are favourable on pain and disability for patients with chronic LBP 11 , 32 , 41 , 49 , 57 and patients after spinal surgery for LBP. 38 ” Reviewer Comment: Discussion: First paragraph: To explain why the classification could be controversial, you could specify that the use of apps is multiple. Author Response: Thank you. We applied your suggestion: “The present review did not aim to firmly classify use of the smartphone apps, as their multiple uses can be controversial.” Reviewer Comment: It's not clear why you use both the words "efficacy" and "effectiveness". Author Response: Thank you for this pertinent remark. We have uniformed the words use trough manuscript. Reviewer Comment: Second paragraph: As stated above, you can't really state about the growing literature as you didn't really study that point. Author Response: We have changed this sentence: “We observed a notable interest in scientific literature regarding the utilization of smartphone apps for patients with LBP.” Reviewer Comment: When you are talking of efficacy or effectiveness, specify systematically on what outcomes. Author Response: Thank you for this remark. In the objective of the present scoping review, we did not specify the outcome of effectiveness, in contrast to what would be appropriate for a systematic review. Our intention was to conduct evaluation of the content of scientific literature including all types of studies and including the effectiveness regarding all types of outcomes. However, we agree that specifying the outcome for effectiveness of the studies we reported would improve the clarity. We added the outcomes when reporting effectiveness through the manuscript. Reviewer Comment: I don't really understand the problem of hygiene raised by the use of apps to measure RoM. Author Response: We have reformulated this sentence: “Using the therapist's personal smartphone to perform measurements on patients may not be practical.” Reviewer Comment: Last paragraph before the limits part, what about data security? Author Response: Thank you for this important remark. We added a sentence about it: “At the same time, it's important to respect data security considerations.” Reviewer Comment: Limitations: I'm not sure that the compulsive behavior is a limitation as it is not really in the scope of your review. Author Response: We removed the part of paragraph referred to smartphone addiction and compulsive behaviour. Reviewer Comment: Conclusions: Same remark about "growing literature". Author Response: We have reformulated the sentence: “The present scoping review revealed that the scientific literature interest in the utilization of smartphone apps for patients with LBP is notable.” View more View less Competing Interests No competing interests were disclosed. reply Respond Report a concern Roren A. Peer Review Report For: Smartphone applications are used for self-management, telerehabilitation, evaluation and data collection in low back pain healthcare: a scoping review [version 2; peer review: 2 approved] . F1000Research 2024, 11 :1001 ( https://doi.org/10.5256/f1000research.135427.r152995) NOTE: it is important to ensure the information in square brackets after the title is included in this citation. The direct URL for this report is: https://f1000research.com/articles/11-1001/v1#referee-response-152995 Alongside their report, reviewers assign a status to the article: Approved - the paper is scientifically sound in its current form and only minor, if any, improvements are suggested Approved with reservations - A number of small changes, sometimes more significant revisions are required to address specific details and improve the papers academic merit. Not approved - fundamental flaws in the paper seriously undermine the findings and conclusions Adjust parameters to alter display View on desktop for interactive features Includes Interactive Elements View on desktop for interactive features Competing Interests Policy Provide sufficient details of any financial or non-financial competing interests to enable users to assess whether your comments might lead a reasonable person to question your impartiality. 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