Endometriosis-associated invasive adenocarcinoma involving the rectum in a postmenopausal female: report of a case

This case report describes a postmenopausal woman who developed invasive endometrioid adenocarcinoma in the rectum twenty-two years after undergoing total abdominal hysterectomy and bilateral salpingo-oophorectomy. The authors document the histologic progression of the disease from endometriosis to complex hyperplasia with cytologic atypia, ultimately resulting in malignancy. They recommend aggressive surgical removal of all visible colorectal endometriosis for patients presenting with advanced disease to manage such transformations. This paper is centrally about endometriosis — specifically its rare malignant transformation into invasive adenocarcinoma within the rectum.

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