P16.07: The risk of preterm delivery of pregnant women with adenomyosis

To evaluate the risk of preterm birth in women with adenomysis during pregnancy A computerized ultrasonography database identified women with adenomyosis at 11 + 0 ∼ 13 + 6 weeks of gestation from January 2010 through December 2012 in Cheil General Hospital. Among them, only cases with known pregnancy outcome were included in this study. We reviewed the medical records of these pregnant women. During the study period, total 11,173 singleton pregnant women underwent routine first trimester ultrasonographic examination for NT measurement in our institute. Among them, adenomysis was detected in 88 pregnant women (0.8 %). Excluding 9 cases of follow-up loss, 79 women were included study population. The rate of preterm birth less than 37 weeks of gestation was significantly increased in study group compared with women without adenomyosis (13.7% vs. 4.6%, P < .05). Furthermore, the risk of delivered before 32 weeks of gestation was also higher in women with adenomyosis (9.6% vs. 0.7%, P < .05). Among women with adenomyosis during pregnancy, the risk of preterm birth seemed to be higher in pregnant women conceived by assisted reproductive technology than in spontaneous conceived group (24.1 vs. 6.8%, P = .078). Gravid women with adenomyosis were associated with increased risk of preterm delivery. When adenomyosis was detected in early ultrasonography, counselling about risk of preterm delivery and meticulous antenatal care should be needed, especially infertile women conceived by assisted reproductive technology.