OC13.05: Assessment of cyst content by using mean grey value for discriminating ovarian endometrioma from other unilocular cysts in premenopausal women

To assess whether the analysis of cyst content using mean grey value (MGV) discriminate ovarian endometriomas from other unilocular ovarian cysts. Stored 3D volumes from 54 unilocular ovarian cysts diagnosed in 50 premenopausal women (mean age: 36.9 years, range: 22 to 54 years) were analysed for calculating MGV from cyst content. No cyst with solid component or septations was included. MGV was calculated in all cases with VOCAL technique using 4D View software. B-Mode presumptive diagnosis based on examiner subjective impression was also recorded. In 16 cases the cysts resolved spontaneously and were considered as hemorrhagic functional cysts. 38 cysts were surgically removed (6 simple cysts, 3 hemorrhagic cysts, 20 endometriomas, 6 mucinous cysts and 2 para-ovarian cysts). B-mode diagnosis were as follows: Simple cyst: 8 cases, hemorrhagic cyst: 17 cases, endometrioma: 24 cases, mucinous cyst: 4 cases and para-ovarian cyst: one case. MGV was significantly higher in ovarian endometrioma as compared with all other kind of cysts (Table). ROC curve showed that a MGV cut-off > 15.566 had a 85% sensitivity and 76.5& specificity for diagnosing ovarian endometrioma (AUC: 0.831, 95% CI: 0.72 to 0.94). These figures were similar to that for B-mode diagnosis (sensitivity: 90%, specificity: 82.4%) (McNemar test: p = 1.000) MGV of cyst content is higher in ovarian endometrioma than in other unilocular ovarian cysts. Its diagnostic performance is similar than subjective examiner's diagnosis.